Best TWAS P=6.57e-10 · Best GWAS P=1.37e-09 conditioned to 0.101
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | TGM2 | 0.13 | 0.05 | lasso | 3 | 0.04 | 4.9e-04 | 4.0 | 5.5 | 4.4e-08 | 0.76 | 0.01 | 0.98 | FALSE |
2 | METSIM | Adipose | TGM2 | 0.09 | 0.05 | enet | 12 | 0.07 | 2.2e-10 | 4.4 | 6.2 | 6.6e-10 | 0.83 | 0.02 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | TGM2 | 0.04 | 0.04 | lasso | 2 | 0.04 | 1.8e-04 | 4.9 | 5.7 | 1.4e-08 | 0.70 | 0.02 | 0.97 | FALSE |