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Traits
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Blood Platelet Count
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chr20:39,114,404-40,516,054
Best TWAS P=1.41e-15 · Best GWAS P=2.13e-22 conditioned to 1.17e-23
39.2M
39.4M
39.6M
39.8M
40M
40.2M
40.4M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
LPIN3
0.10
0.02
lasso
5
0.07
6.1e-04
7.6
8.0
1.4e-15
0.02
0.00
0.76
TRUE
1
GTEx
Adrenal Gland
RP3-511B24.6
0.21
0.00
lasso
5
0.00
2.5e-01
5.4
-6.5
7.2e-11
0.08
0.05
0.22
TRUE
2
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
EMILIN3
0.08
0.06
lasso
5
0.08
2.7e-09
7.3
7.0
2.0e-12
-0.08
0.04
0.96
FALSE
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
ZHX3
0.05
0.06
lasso
2
0.05
2.6e-06
6.1
-5.9
3.0e-09
0.02
0.23
0.76
FALSE
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ZHX3
0.04
0.02
lasso
2
0.02
2.4e-03
5.7
5.2
2.3e-07
-0.07
0.03
0.04
FALSE