Best TWAS P=1.68e-14 · Best GWAS P=9.35e-13 conditioned to 0.369
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Spleen | ANKRD28 | 0.31 | 0.08 | lasso | 6 | 0.07 | 8.3e-03 | 6.7 | 7.7 | 1.7e-14 | 0.94 | 0.02 | 0.94 | TRUE |
| 2 | GTEx | Whole Blood | ANKRD28 | 0.08 | 0.01 | lasso | 2 | 0.00 | 2.0e-01 | 6.8 | 7.0 | 1.9e-12 | 0.96 | 0.02 | 0.91 | FALSE |
| 3 | METSIM | Adipose | ANKRD28 | 0.06 | 0.05 | lasso | 3 | 0.04 | 5.3e-07 | 6.8 | 6.7 | 2.4e-11 | 0.92 | 0.01 | 0.99 | FALSE |
| 4 | NTR | Blood | ANKRD28 | 0.03 | 0.03 | enet | 29 | 0.03 | 6.1e-09 | 7.1 | 5.8 | 6.6e-09 | 0.89 | 0.01 | 0.99 | FALSE |
| 5 | YFS | Blood | ANKRD28 | 0.10 | 0.09 | lasso | 9 | 0.10 | 5.2e-30 | 6.8 | 5.2 | 2.4e-07 | 0.90 | 0.02 | 0.98 | TRUE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | BTD | 0.02 | 0.01 | blup | 40 | 0.00 | 5.1e-02 | -2.4 | -6.0 | 2.2e-09 | -0.68 | 0.01 | 0.36 | FALSE |
| 7 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | BTD | 0.11 | -0.01 | blup | 45 | 0.00 | 2.1e-01 | 4.1 | -6.2 | 7.1e-10 | -0.63 | 0.01 | 0.10 | FALSE |