Best TWAS P=7.88e-08 · Best GWAS P=5.81e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ZNF362 | 0.05 | 0.06 | lasso | 1 | 0.06 | 2.2e-07 | -5.4 | -5.4 | 7.9e-08 | 0.98 | 0.02 | 0.98 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | PHC2 | 0.11 | 0.07 | lasso | 3 | 0.05 | 2.2e-07 | -5.3 | -5.2 | 2.0e-07 | 0.99 | 0.01 | 0.99 | FALSE |