Best TWAS P=1.07e-10 · Best GWAS P=7.11e-14 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LSM10 | 0.08 | 0.00 | blup | 366 | 0.02 | 1.1e-03 | 2.8 | 5.3 | 1.2e-07 | -0.30 | 0.14 | 0.05 | FALSE |
| 2 | GTEx | Artery Tibial | STK40 | 0.06 | 0.03 | lasso | 2 | 0.04 | 4.4e-04 | 4.4 | -5.4 | 6.9e-08 | 0.37 | 0.08 | 0.41 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | SH3D21 | 0.15 | 0.07 | lasso | 5 | 0.08 | 4.7e-07 | -7.5 | -6.5 | 1.1e-10 | 0.94 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | FAM176B | 0.14 | 0.04 | blup | 23 | 0.04 | 1.8e-03 | 4.6 | -5.3 | 1.4e-07 | 0.88 | 0.00 | 0.94 | FALSE |