Best TWAS P=2.56e-09 · Best GWAS P=8.35e-09 conditioned to 0.0141
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | PCOLCE2 | 0.16 | 0.12 | lasso | 4 | 0.12 | 5.5e-14 | -5.6 | -5.3 | 9.0e-08 | -0.64 | 0 | 1 | FALSE |
| 2 | GTEx | Artery Aorta | PCOLCE2 | 0.16 | 0.15 | lasso | 2 | 0.14 | 2.3e-08 | -5.6 | -5.7 | 9.9e-09 | -0.66 | 0 | 1 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PCOLCE2 | 0.13 | 0.14 | lasso | 4 | 0.14 | 2.3e-15 | -5.7 | -6.0 | 2.6e-09 | -0.66 | 0 | 1 | TRUE |