TWAS
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Models
Genes
Traits
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Traits
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Blood Platelet Count
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chr3:193,865,878-194,361,863
Best TWAS P=4.28e-18 · Best GWAS P=1.07e-18 conditioned to 1
193.9M
194M
194.1M
194.2M
194.3M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Thyroid Carcinoma
GP5
0.14
0.17
lasso
5
0.18
5.3e-17
-8.8
8.7
4.3e-18
-0.97
0.00
1.00
TRUE
1
The Cancer Genome Atlas
Testicular Germ Cell Tumors
GP5
0.20
0.10
enet
7
0.14
1.2e-05
-6.8
7.7
1.7e-14
-0.85
0.01
0.98
FALSE