[Hub]/) : Traits : Blood Platelet Count : ← →

chr3:194,678,015-197,133,082

Best TWAS P=2.56e-10 · Best GWAS P=4.56e-23 conditioned to 5.73e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CEP19 0.18 0.10 lasso 6 0.12 1.3e-14 -3.4 5.6 2.7e-08 -0.46 0.97 0.03 FALSE
2 GTEx Adipose Visceral Omentum MUC20 0.12 0.00 enet 22 0.02 2.2e-02 -4.0 -5.5 3.5e-08 -0.03 0.08 0.19 TRUE
3 GTEx Brain Frontal Cortex BA9 CEP19 0.36 0.07 enet 17 0.13 3.3e-04 -3.7 5.3 1.0e-07 -0.47 0.16 0.16 FALSE
4 GTEx Brain Frontal Cortex BA9 SDHAP1 0.26 0.08 lasso 3 0.05 2.4e-02 -5.8 6.2 4.4e-10 0.04 0.03 0.37 TRUE
5 GTEx Breast Mammary Tissue UBXN7 0.20 0.00 enet 16 0.02 3.5e-02 1.6 6.0 2.6e-09 -0.11 0.22 0.06 TRUE
6 GTEx Breast Mammary Tissue (Male) SLC51A 0.62 0.13 enet 76 0.22 7.3e-06 2.9 6.3 2.6e-10 -0.09 0.16 0.08 TRUE
7 GTEx Breast Mammary Tissue (Male) RP11-141C7.3 0.04 0.01 enet 7 0.01 1.9e-01 4.5 -5.9 3.5e-09 0.02 0.02 0.20 FALSE
8 METSIM Adipose PCYT1A 0.05 0.00 bslmm 398 0.02 1.7e-03 -4.0 6.3 2.7e-10 -0.32 0.27 0.13 FALSE
9 The Cancer Genome Atlas Breast Invasive Carcinoma C3orf34 0.03 0.00 blup 60 0.02 6.8e-06 -3.4 6.2 4.5e-10 -0.64 0.36 0.18 TRUE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PAK2 0.04 0.00 blup 82 0.00 1.1e-01 6.6 -5.3 1.0e-07 0.57 0.02 0.25 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma C3orf34 0.05 0.06 enet 10 0.05 2.8e-06 -3.7 6.0 2.1e-09 -0.57 0.85 0.06 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma PAK2 0.03 0.00 blup 83 0.01 1.4e-02 7.0 -5.7 1.1e-08 0.72 0.05 0.37 FALSE