Best TWAS P=5.11e-16 · Best GWAS P=6.07e-15 conditioned to 0.00278
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | OCIAD1 | 0.09 | 0.10 | lasso | 4 | 0.10 | 2.4e-06 | 6.5 | -6.4 | 1.8e-10 | 0.72 | 0.59 | 0.40 | FALSE |
| 2 | GTEx | Artery Tibial | OCIAD1 | 0.09 | 0.12 | enet | 6 | 0.11 | 1.1e-08 | 6.4 | -6.2 | 5.7e-10 | 0.69 | 0.73 | 0.27 | FALSE |
| 3 | GTEx | Artery Tibial | OCIAD1-AS1 | 0.07 | 0.00 | enet | 13 | 0.02 | 7.0e-03 | -6.0 | 6.2 | 4.5e-10 | -0.37 | 0.10 | 0.18 | FALSE |
| 4 | GTEx | Brain Cerebellum | OCIAD1 | 0.10 | 0.04 | lasso | 5 | 0.02 | 1.1e-01 | 6.5 | -8.1 | 5.1e-16 | 0.70 | 0.03 | 0.72 | TRUE |
| 5 | GTEx | Colon Transverse | OCIAD1 | 0.07 | 0.07 | lasso | 5 | 0.05 | 2.8e-03 | 6.4 | -6.2 | 5.9e-10 | 0.70 | 0.31 | 0.43 | FALSE |
| 6 | GTEx | Esophagus Mucosa | OCIAD1 | 0.07 | 0.06 | lasso | 4 | 0.06 | 9.9e-05 | 5.4 | -5.7 | 1.6e-08 | 0.70 | 0.88 | 0.09 | FALSE |
| 7 | GTEx | Esophagus Mucosa | OCIAD1-AS1 | 0.11 | 0.01 | lasso | 7 | 0.01 | 1.2e-01 | -7.1 | 7.3 | 2.0e-13 | -0.66 | 0.05 | 0.49 | FALSE |
| 8 | GTEx | Esophagus Muscularis | OCIAD1 | 0.12 | 0.16 | lasso | 6 | 0.17 | 9.1e-11 | 6.4 | -6.3 | 3.4e-10 | 0.75 | 0.95 | 0.05 | FALSE |
| 9 | GTEx | Nerve Tibial | DCUN1D4 | 0.10 | 0.09 | lasso | 3 | 0.10 | 6.8e-08 | 5.3 | 5.2 | 2.0e-07 | -0.40 | 0.39 | 0.61 | FALSE |
| 10 | GTEx | Ovary | FRYL | 0.12 | -0.01 | enet | 21 | 0.03 | 7.2e-02 | 5.7 | 5.5 | 3.2e-08 | -0.68 | 0.13 | 0.13 | FALSE |
| 11 | GTEx | Thyroid | OCIAD1-AS1 | 0.05 | 0.02 | lasso | 4 | 0.03 | 2.0e-03 | 5.0 | 6.1 | 1.3e-09 | -0.40 | 0.12 | 0.27 | FALSE |
| 12 | NTR | Blood | OCIAD1 | 0.01 | 0.01 | bslmm | 207 | 0.00 | 1.8e-02 | 6.5 | -6.7 | 3.0e-11 | 0.71 | 0.60 | 0.25 | FALSE |
| 13 | ROSMAP | Brain Pre-frontal Cortex | OCIAD1 | 0.06 | 0.07 | enet | 13 | 0.07 | 3.8e-09 | 6.4 | -6.9 | 4.0e-12 | 0.70 | 0.91 | 0.09 | FALSE |
| 14 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | OCIAD1 | 0.05 | 0.03 | enet | 8 | 0.04 | 1.0e-05 | 6.4 | -7.1 | 9.5e-13 | 0.63 | 0.01 | 0.94 | FALSE |
| 15 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SLC10A4 | 0.05 | 0.07 | blup | 36 | 0.07 | 6.0e-08 | 6.7 | 6.8 | 8.7e-12 | -0.64 | 0.60 | 0.40 | FALSE |
| 16 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FRYL | 0.03 | 0.03 | enet | 8 | 0.03 | 3.2e-04 | 6.6 | 5.3 | 1.1e-07 | -0.63 | 0.24 | 0.07 | FALSE |
| 17 | The Cancer Genome Atlas | Thyroid Carcinoma | FRYL | 0.02 | 0.01 | blup | 93 | 0.01 | 3.6e-02 | 6.4 | 6.1 | 8.6e-10 | -0.66 | 0.08 | 0.31 | FALSE |
| 18 | The Cancer Genome Atlas | Thyroid Carcinoma | OCIAD1 | 0.08 | 0.05 | enet | 16 | 0.06 | 8.5e-07 | 6.5 | -6.4 | 1.3e-10 | 0.58 | 0.01 | 0.98 | FALSE |