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chr4:47,802,595-53,472,171

Best TWAS P=5.11e-16 · Best GWAS P=6.07e-15 conditioned to 0.00278

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Brain Cerebellum	OCIAD1	0.10	0.04	lasso	5	0.02	1.1e-01	6.5	-8.1	5.1e-16	0.70	0.03	0.72	TRUE
7	GTEx	Esophagus Mucosa	OCIAD1-AS1	0.11	0.01	lasso	7	0.01	1.2e-01	-7.1	7.3	2.0e-13	-0.66	0.05	0.49	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	OCIAD1	0.05	0.03	enet	8	0.04	1.0e-05	6.4	-7.1	9.5e-13	0.63	0.01	0.94	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	OCIAD1	0.06	0.07	enet	13	0.07	3.8e-09	6.4	-6.9	4.0e-12	0.70	0.91	0.09	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC10A4	0.05	0.07	blup	36	0.07	6.0e-08	6.7	6.8	8.7e-12	-0.64	0.60	0.40	FALSE
12	NTR	Blood	OCIAD1	0.01	0.01	bslmm	207	0.00	1.8e-02	6.5	-6.7	3.0e-11	0.71	0.60	0.25	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	OCIAD1	0.08	0.05	enet	16	0.06	8.5e-07	6.5	-6.4	1.3e-10	0.58	0.01	0.98	FALSE
1	GTEx	Artery Aorta	OCIAD1	0.09	0.10	lasso	4	0.10	2.4e-06	6.5	-6.4	1.8e-10	0.72	0.59	0.40	FALSE
8	GTEx	Esophagus Muscularis	OCIAD1	0.12	0.16	lasso	6	0.17	9.1e-11	6.4	-6.3	3.4e-10	0.75	0.95	0.05	FALSE
3	GTEx	Artery Tibial	OCIAD1-AS1	0.07	0.00	enet	13	0.02	7.0e-03	-6.0	6.2	4.5e-10	-0.37	0.10	0.18	FALSE
2	GTEx	Artery Tibial	OCIAD1	0.09	0.12	enet	6	0.11	1.1e-08	6.4	-6.2	5.7e-10	0.69	0.73	0.27	FALSE
5	GTEx	Colon Transverse	OCIAD1	0.07	0.07	lasso	5	0.05	2.8e-03	6.4	-6.2	5.9e-10	0.70	0.31	0.43	FALSE
17	The Cancer Genome Atlas	Thyroid Carcinoma	FRYL	0.02	0.01	blup	93	0.01	3.6e-02	6.4	6.1	8.6e-10	-0.66	0.08	0.31	FALSE
11	GTEx	Thyroid	OCIAD1-AS1	0.05	0.02	lasso	4	0.03	2.0e-03	5.0	6.1	1.3e-09	-0.40	0.12	0.27	FALSE
6	GTEx	Esophagus Mucosa	OCIAD1	0.07	0.06	lasso	4	0.06	9.9e-05	5.4	-5.7	1.6e-08	0.70	0.88	0.09	FALSE
10	GTEx	Ovary	FRYL	0.12	-0.01	enet	21	0.03	7.2e-02	5.7	5.5	3.2e-08	-0.68	0.13	0.13	FALSE
16	The Cancer Genome Atlas	Prostate Adenocarcinoma	FRYL	0.03	0.03	enet	8	0.03	3.2e-04	6.6	5.3	1.1e-07	-0.63	0.24	0.07	FALSE
9	GTEx	Nerve Tibial	DCUN1D4	0.10	0.09	lasso	3	0.10	6.8e-08	5.3	5.2	2.0e-07	-0.40	0.39	0.61	FALSE