[Hub]/) : Traits : Blood Platelet Count :

chr4:37,915,462-39,483,162

Best TWAS P=2.83e-14 · Best GWAS P=8e-14 conditioned to 0.924

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous AC021860.1 0.32 0.28 enet 20 0.36 2.7e-30 -4.4 -6.0 1.8e-09 0.71 0.96 0.04 FALSE
2 GTEx Adipose Subcutaneous RP11-617D20.1 0.28 0.26 lasso 6 0.28 2.4e-23 -4.8 -6.2 4.9e-10 0.71 0.98 0.02 FALSE
3 GTEx Adipose Visceral Omentum AC021860.1 0.33 0.08 lasso 9 0.13 3.2e-07 -4.4 -5.8 7.2e-09 0.57 0.18 0.78 FALSE
4 GTEx Adipose Visceral Omentum RP11-617D20.1 0.31 0.10 enet 21 0.17 3.9e-09 -4.8 -6.1 1.1e-09 0.49 0.84 0.15 FALSE
5 GTEx Adrenal Gland AC021860.1 0.30 0.11 lasso 5 0.12 4.1e-05 -4.9 -5.2 1.8e-07 0.53 0.08 0.73 FALSE
6 GTEx Artery Aorta AC021860.1 0.34 0.14 lasso 4 0.32 6.5e-18 -7.5 -6.2 4.2e-10 0.77 0.00 1.00 FALSE
7 GTEx Artery Aorta RP11-617D20.1 0.27 0.18 lasso 6 0.24 1.6e-13 -4.4 -6.6 3.2e-11 0.82 0.01 0.99 FALSE
8 GTEx Artery Tibial AC021860.1 0.30 0.09 enet 30 0.22 1.5e-17 -4.4 -6.2 6.3e-10 0.63 0.12 0.88 FALSE
9 GTEx Artery Tibial RP11-617D20.1 0.32 0.23 enet 39 0.28 5.0e-22 -4.4 -6.3 2.2e-10 0.78 0.04 0.96 FALSE
10 GTEx Brain Cerebellar Hemisphere AC021860.1 0.50 0.30 lasso 6 0.34 1.7e-09 -7.5 -6.7 1.8e-11 0.89 0.00 1.00 FALSE
11 GTEx Brain Cerebellar Hemisphere RP11-617D20.1 0.53 0.25 lasso 8 0.32 5.1e-09 -7.5 -5.2 2.3e-07 0.83 0.00 0.99 FALSE
12 GTEx Brain Cerebellum AC021860.1 0.63 0.33 lasso 16 0.43 5.7e-14 -7.5 -7.1 1.6e-12 0.83 0.00 1.00 FALSE
13 GTEx Brain Cerebellum RP11-617D20.1 0.59 0.23 lasso 8 0.39 1.0e-12 -7.5 -6.5 6.8e-11 0.80 0.00 1.00 FALSE
14 GTEx Brain Cortex AC021860.1 0.42 0.32 lasso 3 0.38 1.3e-11 3.0 -5.2 2.3e-07 0.65 0.09 0.91 FALSE
15 GTEx Brain Frontal Cortex BA9 RP11-617D20.1 0.34 0.14 lasso 4 0.14 1.7e-04 -7.5 -6.5 7.6e-11 0.84 0.01 0.97 FALSE
16 GTEx Brain Nucleus accumbens basal ganglia AC021860.1 0.37 0.05 enet 20 0.12 5.2e-04 3.0 -5.7 1.2e-08 0.63 0.02 0.93 FALSE
17 GTEx Brain Nucleus accumbens basal ganglia RP11-617D20.1 0.65 0.14 lasso 14 0.27 7.6e-08 -7.5 -6.5 6.2e-11 0.75 0.00 0.99 FALSE
18 GTEx Brain Putamen basal ganglia RP11-617D20.1 0.44 0.12 lasso 7 0.26 8.3e-07 -7.5 -5.6 2.3e-08 0.77 0.00 0.99 FALSE
19 GTEx Breast Mammary Tissue AC021860.1 0.49 0.13 enet 29 0.27 2.2e-14 -4.4 -5.4 8.2e-08 0.55 0.68 0.31 FALSE
20 GTEx Colon Sigmoid RP11-617D20.1 0.45 0.34 lasso 8 0.34 9.5e-13 -4.8 -5.8 8.9e-09 0.65 0.33 0.66 FALSE
21 GTEx Colon Transverse AC021860.1 0.32 0.10 lasso 10 0.07 2.4e-04 -4.9 -6.0 2.0e-09 0.71 0.03 0.96 FALSE
22 GTEx Esophagus Gastroesophageal Junction AC021860.1 0.23 0.11 enet 14 0.11 8.9e-05 -4.4 -6.2 6.7e-10 0.68 0.03 0.96 FALSE
23 GTEx Esophagus Muscularis AC021860.1 0.40 0.19 enet 24 0.36 3.9e-23 -4.4 -6.1 8.9e-10 0.72 0.01 0.99 FALSE
24 GTEx Esophagus Muscularis RP11-617D20.1 0.35 0.26 lasso 6 0.31 2.5e-19 -4.3 -6.3 2.4e-10 0.77 0.04 0.96 FALSE
25 GTEx Heart Atrial Appendage AC021860.1 0.48 0.07 lasso 15 0.19 8.1e-09 -4.8 -6.0 1.5e-09 0.72 0.01 0.99 FALSE
26 GTEx Heart Atrial Appendage RP11-617D20.1 0.29 0.14 lasso 6 0.17 3.7e-08 -4.8 -6.8 1.2e-11 0.82 0.01 0.99 FALSE
27 GTEx Heart Left Ventricle AC021860.1 0.26 0.15 lasso 5 0.19 1.4e-10 -7.5 -7.2 5.8e-13 0.90 0.00 1.00 FALSE
28 GTEx Heart Left Ventricle RP11-617D20.1 0.28 0.14 lasso 5 0.14 6.8e-08 -4.9 -6.0 1.4e-09 0.68 0.14 0.86 FALSE
29 GTEx Lung AC021860.1 0.19 0.07 enet 14 0.14 8.2e-11 -7.5 -7.0 3.7e-12 0.81 0.00 1.00 FALSE
30 GTEx Lung RP11-617D20.1 0.19 0.14 enet 9 0.14 1.3e-10 -4.4 -5.7 9.9e-09 0.67 0.30 0.70 FALSE
31 GTEx Muscle Skeletal AC021860.1 0.16 0.10 lasso 7 0.13 1.1e-12 -7.5 -7.5 8.6e-14 0.85 0.00 1.00 FALSE
32 GTEx Nerve Tibial AC021860.1 0.43 0.20 lasso 13 0.30 8.5e-22 3.0 -6.2 7.0e-10 0.72 0.26 0.74 FALSE
33 GTEx Nerve Tibial RP11-617D20.1 0.35 0.10 enet 81 0.20 7.0e-14 -4.3 -5.9 3.0e-09 0.53 0.01 0.99 FALSE
34 GTEx Pancreas AC021860.1 0.41 0.33 lasso 6 0.44 5.0e-20 -7.5 -7.0 3.8e-12 0.87 0.00 1.00 FALSE
35 GTEx Pancreas RP11-617D20.1 0.34 0.27 lasso 6 0.33 1.8e-14 -7.5 -7.1 1.1e-12 0.88 0.00 1.00 FALSE
36 GTEx Prostate AC021860.1 0.28 0.15 enet 29 0.28 8.1e-08 -7.5 -6.2 4.1e-10 0.66 0.00 0.98 FALSE
37 GTEx Skin Not Sun Exposed Suprapubic AC021860.1 0.43 0.32 lasso 8 0.35 4.0e-20 -4.4 -5.5 3.7e-08 0.69 0.59 0.41 FALSE
38 GTEx Skin Sun Exposed Lower leg RP11-617D20.1 0.20 0.10 lasso 4 0.11 3.2e-09 -4.4 -6.2 5.6e-10 0.75 0.10 0.90 FALSE
39 GTEx Stomach AC021860.1 0.37 0.14 enet 27 0.18 5.9e-09 -4.8 -5.6 2.1e-08 0.56 0.26 0.72 FALSE
40 GTEx Stomach RP11-617D20.1 0.32 0.23 enet 13 0.20 6.5e-10 -4.8 -5.5 4.0e-08 0.58 0.70 0.30 FALSE
41 GTEx Testis AC021860.1 0.23 0.16 lasso 5 0.23 1.3e-10 -4.3 -6.3 3.2e-10 0.75 0.02 0.98 FALSE
42 GTEx Testis RP11-617D20.1 0.28 0.16 lasso 5 0.18 1.9e-08 -4.3 -5.7 1.5e-08 0.76 0.01 0.99 FALSE
43 GTEx Thyroid AC021860.1 0.30 0.22 lasso 4 0.30 5.4e-23 3.0 -5.2 2.5e-07 0.58 0.99 0.01 FALSE
44 GTEx Thyroid RP11-617D20.1 0.31 0.22 enet 20 0.29 3.5e-22 -4.8 -6.1 1.1e-09 0.71 0.17 0.83 FALSE
45 GTEx Vagina RP11-617D20.1 0.31 0.01 lasso 8 0.02 1.4e-01 -4.3 -6.4 1.6e-10 0.79 0.02 0.69 FALSE
46 GTEx Whole Blood AC021860.1 0.14 0.07 lasso 7 0.10 2.5e-09 -4.4 -6.1 8.5e-10 0.72 0.04 0.96 FALSE
47 GTEx Whole Blood RP11-617D20.1 0.14 0.06 lasso 3 0.05 4.2e-05 5.5 -6.2 4.0e-10 0.78 0.02 0.97 FALSE
48 METSIM Adipose AC021860.1 0.18 0.07 bslmm 596 0.12 4.0e-17 -4.3 -6.7 1.6e-11 0.75 0.20 0.80 FALSE
49 ROSMAP Brain Pre-frontal Cortex TLR10 0.08 0.01 blup 517 0.03 3.4e-05 -2.7 6.7 2.1e-11 -0.56 0.70 0.12 TRUE
50 ROSMAP Brain Pre-frontal Cortex RP11-617D20.1 0.14 0.08 enet 18 0.13 6.8e-16 -4.8 -6.6 3.7e-11 0.73 0.01 0.99 FALSE
51 The Cancer Genome Atlas Breast Invasive Carcinoma FLJ13197 0.04 0.02 blup 80 0.03 3.2e-07 -4.3 -6.8 1.3e-11 0.76 0.25 0.75 FALSE
52 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FLJ13197 0.14 0.00 blup 81 0.04 6.7e-03 2.8 -6.5 8.1e-11 0.60 0.02 0.14 FALSE
53 The Cancer Genome Atlas Colon Adenocarcinoma FLJ13197 0.12 0.00 blup 85 0.05 9.1e-04 -4.4 -5.7 9.5e-09 0.51 0.08 0.45 FALSE
54 The Cancer Genome Atlas Esophageal Carcinoma FLJ13197 0.16 0.04 lasso 2 0.02 8.9e-02 -7.5 -7.5 7.5e-14 1.00 0.00 0.90 FALSE
55 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FLJ13197 0.11 0.07 blup 85 0.10 3.4e-11 -4.4 -6.5 7.8e-11 0.71 0.09 0.91 FALSE
56 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FLJ13197 0.08 0.05 blup 85 0.03 6.4e-03 -4.3 -5.4 5.9e-08 0.58 0.09 0.75 FALSE
57 The Cancer Genome Atlas Brain Lower Grade Glioma FLJ13197 0.06 0.04 enet 9 0.06 1.3e-07 -7.5 -7.3 2.2e-13 0.83 0.00 1.00 FALSE
58 The Cancer Genome Atlas Lung Adenocarcinoma FLJ13197 0.11 0.07 blup 85 0.08 7.0e-10 -4.4 -5.9 3.3e-09 0.62 0.16 0.84 FALSE
59 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FLJ13197 0.08 0.04 enet 11 0.06 1.7e-07 -4.4 -6.1 8.9e-10 0.74 0.03 0.97 FALSE
60 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FLJ13197 0.06 0.00 blup 81 0.01 3.4e-02 -4.9 -7.6 2.8e-14 0.84 0.01 0.83 TRUE
61 The Cancer Genome Atlas Pancreatic Adenocarcinoma FLJ13197 0.13 0.07 blup 81 0.08 2.7e-04 -7.5 -6.8 1.4e-11 0.74 0.00 0.96 FALSE
62 The Cancer Genome Atlas Prostate Adenocarcinoma FLJ13197 0.20 0.10 blup 81 0.14 4.2e-14 -4.8 -5.7 1.0e-08 0.62 0.65 0.35 FALSE
63 The Cancer Genome Atlas Soft Tissue Sarcoma FLJ13197 0.08 0.02 enet 9 0.04 1.7e-03 -6.4 -7.1 1.3e-12 0.67 0.03 0.42 FALSE
64 The Cancer Genome Atlas Testicular Germ Cell Tumors FLJ13197 0.22 0.05 blup 85 0.10 2.4e-04 3.4 -6.0 1.9e-09 0.71 0.02 0.58 FALSE
65 The Cancer Genome Atlas Thyroid Carcinoma FLJ13197 0.16 0.08 blup 82 0.13 7.1e-13 -7.5 -6.5 9.3e-11 0.74 0.00 1.00 FALSE
66 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma FLJ13197 0.20 0.01 blup 85 0.09 1.4e-03 -4.4 -7.0 2.0e-12 0.83 0.01 0.86 FALSE