Best TWAS P=2.05e-12 · Best GWAS P=4.23e-14 conditioned to 1.28e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | RCHY1 | 0.15 | 0.09 | bslmm | 441 | 0.09 | 2.3e-11 | -6.9 | -5.6 | 2.6e-08 | -0.22 | 0.31 | 0.69 | FALSE |
2 | GTEx | Adipose Subcutaneous | RCHY1 | 0.10 | 0.09 | lasso | 5 | 0.07 | 1.3e-06 | -6.7 | -6.5 | 9.6e-11 | -0.33 | 0.30 | 0.70 | FALSE |
3 | GTEx | Cells Transformed fibroblasts | RCHY1 | 0.26 | 0.22 | lasso | 4 | 0.22 | 8.6e-17 | -7.0 | -7.0 | 2.0e-12 | -0.38 | 0.23 | 0.77 | TRUE |