TWAS
hub
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Usage
Models
Genes
Traits
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Traits
:
Blood Platelet Count
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chr4:83,124,080-84,633,401
Best TWAS P=8.51e-14 · Best GWAS P=7e-14 conditioned to 0.144
83.2M
83.4M
83.6M
83.8M
84M
84.2M
84.4M
84.6M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Breast Mammary Tissue
THAP9-AS1
0.16
0.12
lasso
6
0.11
2.7e-06
7.3
7.5
8.5e-14
0.93
0.01
0.98
TRUE
1
CommonMind
Brain Pre-frontal Cortex
LIN54
0.06
0.08
lasso
2
0.07
1.1e-08
7.3
-7.3
2.5e-13
-0.98
0.02
0.98
FALSE
3
GTEx
Breast Mammary Tissue (Female)
THAP9-AS1
0.07
0.07
lasso
1
0.02
8.4e-02
7.3
7.3
2.6e-13
0.93
0.02
0.78
FALSE
4
GTEx
Nerve Tibial
THAP9-AS1
0.08
0.00
enet
7
0.01
5.3e-02
-2.8
5.4
6.9e-08
0.69
0.06
0.69
FALSE