Best TWAS P=8.51e-14 · Best GWAS P=7e-14 conditioned to 0.144
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LIN54 | 0.06 | 0.08 | lasso | 2 | 0.07 | 1.1e-08 | 7.3 | -7.3 | 2.5e-13 | -0.98 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | THAP9-AS1 | 0.16 | 0.12 | lasso | 6 | 0.11 | 2.7e-06 | 7.3 | 7.5 | 8.5e-14 | 0.93 | 0.01 | 0.98 | TRUE |
| 3 | GTEx | Breast Mammary Tissue (Female) | THAP9-AS1 | 0.07 | 0.07 | lasso | 1 | 0.02 | 8.4e-02 | 7.3 | 7.3 | 2.6e-13 | 0.93 | 0.02 | 0.78 | FALSE |
| 4 | GTEx | Nerve Tibial | THAP9-AS1 | 0.08 | 0.00 | enet | 7 | 0.01 | 5.3e-02 | -2.8 | 5.4 | 6.9e-08 | 0.69 | 0.06 | 0.69 | FALSE |