TWAS hub - RCHY1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1540	0.0360	1.6e-09	0.094	0.088	0.085	0.093	0.093	1.7e-11	7.8e-11	1.5e-10	2.3e-11	2.3e-11
2	GTEx	Adipose Subcutaneous	0.1040	0.0390	1.8e-03	0.089	NA	0.069	NA	0.073	8.9e-08	NA	2.6e-06	NA	1.3e-06
3	GTEx	Artery Tibial	0.0939	0.0373	2.4e-03	0.052	NA	0.100	NA	0.095	6.7e-05	NA	3.0e-08	NA	7.0e-08
4	GTEx	Cells Transformed fibroblasts	0.2580	0.0590	5.1e-09	0.216	NA	0.224	NA	0.225	3.8e-16	NA	9.9e-17	NA	8.6e-17
5	GTEx	Testis	0.2160	0.0710	2.8e-04	0.161	NA	0.147	NA	0.162	1.3e-07	NA	4.5e-07	NA	1.2e-07
6	ROSMAP	Brain Pre-frontal Cortex	0.5590	0.0452	0.0e+00	0.355	0.428	0.487	0.424	0.489	1.2e-47	3.8e-60	1.9e-71	2.5e-59	9.3e-72
7	YFS	Blood	0.1739	0.0300	0.0e+00	0.099	0.132	0.143	0.142	0.143	1.4e-30	7.6e-41	2.3e-44	3.0e-44	1.8e-44
8	TCGA	Ovarian Serous Cystadenocarcinoma	0.0600	0.0380	4.4e-03	0.009	0.013	0.007	NA	0.003	7.3e-02	4.0e-02	1.1e-01	NA	1.8e-01
9	TCGA	Stomach Adenocarcinoma	0.0590	0.0400	3.5e-03	0.006	0.019	0.002	NA	0.005	1.0e-01	1.4e-02	2.1e-01	NA	1.3e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Depression (self-reported)	7.8	9.4	12.4	-2.7	-2.0	-3.4	-2.0	3.5	3.5	-3.2	-3.5	-3.2
Noisy workplace	4.0	4.9	7.5	-1.6	-1.3	-2.7	-1.2	2.7	2.7	-2.7	-1.9	-2.3
Lupus	3.9	5.9	10.7	-1.4	-0.9	-2.5	-0.8	3.1	3.3	-2.4	-2.9	-3.0
Neck or shoulder pain in last month	3.8	5.4	8.9	-2.4	-1.3	-2.9	-1.2	2.5	3.0	-2.4	-2.0	-2.5
Medication: Co-codamol	3.5	4.0	7.6	-2.4	-2.8	-2.2	-2.6	0.6	1.5	-2.5	-0.3	-1.5
Age at last live birth	3.4	5.0	8.6	1.7	1.3	2.2	1.3	-2.9	-2.5	2.2	2.8	2.5
Tinnitus: Yes, now most or all of the time	3.4	4.0	10.5	-0.6	-0.6	-0.9	-0.3	3.2	2.0	-1.4	-3.1	-2.9
Frequency of depressed mood in last 2 weeks	3.1	4.3	6.3	-1.9	-2.3	-1.8	-2.3	1.9	1.5	-2.1	-2.5	-2.3
Seen a psychiatrist for nerves, anxiety, tension or depression	3.1	4.1	5.9	-2.1	-1.7	-2.4	-1.6	2.0	2.0	-2.3	-1.6	-2.2
Mother’s age at death	2.9	3.7	6.4	2.5	2.5	2.4	2.3	-0.5	-1.5	2.2	0.9	1.2
Illnesses of siblings: Diabetes	2.7	3.3	6.0	-1.0	-1.4	-1.8	-1.4	1.9	2.1	-1.7	-2.1	-2.5
Risk taking	2.6	3.8	6.5	2.6	1.4	2.4	1.5	-1.4	-2.3	2.2	1.5	1.8
Average weekly spirits intake	2.5	3.1	5.0	-1.9	-1.4	-1.8	-1.5	1.4	2.1	-1.6	-2.2	-1.7
Ever had prostate specific antigen (PSA) test	2.5	2.8	4.6	0.9	1.3	1.9	0.9	-1.5	-2.1	1.6	2.1	2.1
Qualifications: None of the above	2.4	5.2	9.5	-2.5	-2.9	-2.3	-3.1	1.3	1.6	-2.4	-1.8	-2.0
Miserableness	2.4	4.1	6.2	-1.7	-2.0	-1.7	-2.1	2.2	1.5	-2.0	-2.3	-2.5
Taking other prescription medications	2.2	3.3	5.5	-1.9	-1.7	-2.3	-1.5	1.7	2.0	-2.3	-1.0	-1.7
Stomach or abdominal pain in last month	2.2	2.8	5.0	-1.4	-2.2	-2.0	-2.0	1.0	1.3	-2.0	-0.8	-1.6
Blood clot in the leg (DVT)	2.2	2.9	4.5	2.1	2.0	1.5	1.8	-1.5	-1.3	1.9	1.4	1.6
Migraine (self-reported)	2.2	2.8	6.9	0.1	1.1	-1.1	0.9	2.6	2.5	-0.9	-2.2	-1.8
Medication: Seretide 50 evohaler	2.1	2.4	7.0	2.1	2.5	1.0	2.6	-0.1	0.2	1.2	1.1	0.2
Bipolar Disorder (2018)	2.0	3.1	6.1	2.5	1.8	2.4	1.9	-0.9	-1.7	2.0	1.2	0.6
Number of treatments/medications taken	2.0	3.6	6.5	-1.9	-1.0	-1.8	-1.1	2.5	2.2	-2.0	-2.1	-2.1
Serious illness, injury or assault to yourself	2.0	2.5	6.5	2.2	2.5	1.4	2.5	0.0	-0.2	1.4	0.9	0.1
Diabetes (self-reported)	2.0	3.0	6.1	-1.4	-2.5	-1.5	-2.4	1.1	1.2	-1.7	-1.6	-1.7
Deep venous thrombosis (DVT) (self-reported)	2.0	2.6	4.3	2.1	1.9	1.4	1.6	-1.5	-1.2	1.8	1.2	1.5
Rheumatoid Arthritis	1.9	2.6	3.6	-1.9	-1.8	-1.8	-1.6	1.3	1.3	-1.7	-1.5	-1.4
Number of full brothers	1.9	2.3	6.6	-1.5	-2.6	-1.8	-2.0	-0.5	0.7	-1.8	0.3	-0.9
Knee pain experienced in last month	1.9	2.9	5.6	-1.8	-0.9	-2.4	-0.9	1.9	2.1	-2.1	-0.9	-1.5
Illnesses of father: High blood pressure	1.9	2.4	4.3	-0.9	-1.4	-1.6	-1.1	1.8	1.6	-1.7	-1.4	-2.1
Age at First Birth	1.8	2.6	6.9	0.8	0.6	2.5	0.4	-1.0	-2.6	1.7	1.2	1.9
Type 2 Diabetes (T2D) (2018)	1.8	3.4	7.5	-1.3	-2.7	-1.4	-2.4	1.2	1.1	-1.7	-1.8	-2.2
Hypothyroidism (self reported)	1.7	4.0	6.2	-1.1	-1.6	-2.2	-1.4	2.3	2.2	-2.5	-1.8	-2.5
Breastfed as a baby	1.7	2.1	6.2	2.5	1.7	1.6	1.6	-0.7	-1.0	1.5	0.3	0.8
Emphysema/chronic bronchitis	1.7	1.9	5.0	2.2	2.1	0.7	2.2	-0.1	0.0	0.9	0.9	0.7
Medication: Gliclazide	1.7	1.9	3.1	-0.9	-0.9	-1.3	-0.9	1.8	1.6	-1.1	-1.7	-1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.7	3.6	5.9	-2.4	-1.6	-2.4	-1.7	1.7	1.7	-2.3	-1.5	-1.2
Depressed Affect (Nagel 2018)	1.6	3.3	6.7	-1.8	-2.3	-1.6	-2.6	1.0	1.2	-1.7	-1.6	-2.0
Depression (Nagel 2018)	1.6	2.4	3.9	-1.4	-1.9	-1.4	-2.0	1.7	0.9	-1.7	-1.4	-1.5
Hand grip strength (left)	1.6	4.2	8.5	-2.9	-1.6	-2.9	-1.9	1.6	2.2	-2.4	-1.2	-0.6
Bilateral oophorectomy (both ovaries removed)	1.6	1.9	7.1	-0.1	0.8	-0.2	0.9	2.7	1.4	-0.7	-1.7	-1.8
Number of incorrect matches in round	1.6	2.6	5.3	2.3	2.1	2.0	2.1	-0.2	-0.9	2.0	0.6	0.1
Peak expiratory flow (PEF)	1.6	3.8	6.1	-1.4	-1.4	-1.8	-1.1	2.2	2.2	-2.0	-2.4	-2.5
Number of self-reported non-cancer illnesses	1.6	2.8	3.6	-1.7	-1.5	-1.7	-1.4	1.8	1.9	-1.8	-1.4	-1.7
Age started oral contraceptive pill	1.6	2.0	4.9	1.0	2.0	1.3	2.2	-1.0	-0.7	1.5	1.2	1.1
Alcohol drinker status: Previous	1.6	1.8	2.7	-0.9	-1.2	-1.3	-1.0	1.3	1.5	-1.4	-1.7	-1.6
Fasting Glucose	1.5	1.8	6.1	0.6	0.6	-0.3	0.8	2.5	1.3	-0.8	-1.8	-1.8
Blood Platelet Count	1.5	17.1	49.4	-5.6	-6.5	-3.1	-7.0	-3.2	-1.0	-2.8	1.2	1.3
Exposure to tobacco smoke at home	1.5	1.7	4.4	0.3	0.5	-0.7	0.5	2.1	1.8	-0.6	-1.4	-2.0
Handedness (chirality/laterality): Left-handed	1.5	1.8	5.7	2.4	1.1	1.6	1.4	-0.5	-1.3	1.3	1.0	0.6
Age when periods started (menarche)	1.4	3.5	8.3	0.8	0.7	1.1	0.9	-2.4	-2.2	1.1	2.8	2.9
Medication: Levothyroxine sodium	1.4	2.3	4.6	-1.4	-1.4	-2.1	-1.4	0.8	1.8	-1.8	-1.3	-1.2
Medication: Lansoprazole	1.4	1.6	3.5	-1.3	-1.9	-1.4	-1.4	0.7	0.7	-1.7	0.2	-1.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.4	4.3	7.1	-2.1	-2.0	-2.7	-2.1	1.3	2.1	-2.4	-2.1	-1.6
Medication for pain relief, constipation, heartburn	1.4	2.5	6.1	-0.3	-0.5	0.7	-0.4	-2.4	-2.0	0.9	2.1	2.5
Ulcerative Colitis (UC)	1.3	2.4	5.9	0.1	0.7	1.5	0.9	-2.4	-1.5	1.9	1.6	1.8
Supplements: Zinc	1.3	1.4	3.2	1.8	1.2	1.7	1.2	0.7	-0.8	1.2	-0.9	-0.5
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	3.3	1.4	1.8	1.4	1.5	-0.3	-0.6	1.5	0.7	0.9
Loud music exposure frequency	1.3	1.5	4.4	-0.5	-0.9	-0.5	-0.5	2.1	1.0	-1.3	-1.5	-1.6
Average weekly red wine intake	1.3	1.9	4.4	0.4	1.4	0.8	1.2	-1.4	-1.1	1.0	2.1	2.0
Ever smoked	1.3	2.3	5.2	1.0	1.0	-0.8	0.9	1.7	2.3	-0.4	-1.9	-2.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.6	2.4	-1.3	-1.2	-1.1	-1.5	1.6	0.7	-1.3	-1.2	-1.2
High blood pressure (mother)	1.2	1.7	4.7	0.7	0.4	-0.3	0.8	1.6	1.7	-0.4	-2.2	-2.0
Asthma	1.2	2.3	6.4	-0.9	-0.3	-1.1	0.1	2.5	1.8	-1.3	-1.4	-2.3
Glaucoma (self-reported)	1.2	1.4	3.7	0.9	1.1	1.9	1.0	-0.5	-1.5	1.6	0.8	0.7
Loneliness, isolation	1.2	1.6	3.8	-1.2	-1.3	-0.5	-1.4	1.4	0.6	-0.9	-1.6	-1.9
Diabetes diagnosed by doctor	1.2	2.0	3.3	-0.9	-1.8	-1.5	-1.8	1.0	1.3	-1.5	-1.4	-1.5
Asthma (self-reported)	1.2	2.3	5.7	-1.2	-0.5	-1.1	-0.1	2.4	1.8	-1.4	-1.4	-2.3
Qualifications: CSEs or equivalent	1.1	1.5	3.9	-0.1	-0.7	-0.6	-0.5	2.0	1.2	-0.6	-1.9	-1.8
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.5	5.4	0.6	0.0	-0.5	-0.1	1.5	1.2	-0.6	-2.3	-1.7
Medication: Cholesterol lowering	1.1	1.7	3.1	-1.2	-0.6	-1.7	-0.9	1.8	1.6	-1.5	-0.7	-1.2
Heart disease (mother)	1.1	1.3	2.5	-1.6	-1.3	-0.7	-1.4	1.1	0.4	-1.0	-1.4	-0.9
Smoking status: Previous	1.1	1.6	3.4	-1.0	-0.5	-1.4	-0.5	1.4	1.9	-1.2	-1.0	-1.8
Myopia	1.1	1.6	4.1	0.2	0.5	-0.4	0.8	2.0	1.4	-0.7	-1.7	-1.8
Verbal and Numeric Reasoning (VNR)	1.0	2.3	5.0	-2.0	-2.2	-1.7	-2.2	-0.3	0.3	-1.9	0.1	-0.1
Smoking Status	1.0	2.4	7.3	1.1	1.0	-1.2	1.0	1.5	2.7	-0.4	-1.8	-2.0
Respiratory disease	1.0	2.3	5.5	-0.6	-0.1	-1.3	0.2	2.3	2.1	-1.1	-1.5	-2.2
Vitamin and mineral supplements	1.0	1.3	2.6	0.6	1.1	0.8	0.9	-1.3	-0.8	1.4	1.6	1.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	4.4	1.6	1.8	0.5	2.1	0.6	0.6	0.7	-0.2	-0.2
Medication: Ramipril	1.0	1.3	3.4	0.4	-0.3	1.2	-0.3	-1.2	-1.8	0.7	1.6	1.4
Neuroticism score	1.0	2.1	5.3	-0.8	-1.7	-1.2	-1.4	1.4	1.0	-1.5	-1.2	-2.3
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	4.5	-1.8	-1.3	-2.1	-1.4	1.9	2.0	-2.0	-2.0	-1.6
Pulse rate	1.0	1.7	5.6	0.3	-0.2	1.7	-0.2	-1.1	-2.4	0.8	1.6	1.5
Hypothyroidism/myxoedema (self-reported)	1.0	2.0	3.6	-1.2	-1.5	-1.9	-1.6	0.7	1.4	-1.8	-0.9	-1.1
Medication: Ibuprofen	1.0	1.2	4.0	0.6	0.5	-0.1	0.5	1.6	1.0	-0.4	-2.0	-1.6
Overall health rating	1.0	2.2	5.4	-1.6	-2.3	-1.3	-2.0	0.6	0.9	-1.5	-0.6	-1.5
Commuting to job workplace: Cycle	1.0	1.2	1.9	1.2	1.4	1.4	1.1	-1.0	-0.9	1.4	0.4	0.8
Schizophrenia vs Biploar Disorder	0.9	1.2	3.6	-1.9	-1.7	-0.8	-1.6	-0.6	-0.3	-0.8	0.6	0.0
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	1.6	0.8	1.2	0.9	1.3	-0.9	-0.6	1.2	1.0	1.0
Had other major operations	0.9	1.1	2.9	-1.7	-0.7	-0.9	-1.1	1.2	0.6	-1.3	-0.8	-0.3
Lung cancer (father)	0.9	1.1	2.0	0.9	1.1	0.1	1.1	1.3	1.0	0.0	-1.4	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.4	3.4	-0.2	-0.4	-1.4	-0.3	1.7	1.4	-1.5	-0.7	-1.8
Headache pain in last month	0.9	1.6	3.5	0.7	1.6	0.2	1.7	1.9	1.2	0.2	-1.5	-1.0
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	3.4	-1.5	-1.8	-0.7	-1.5	-0.7	-0.3	-0.8	-0.4	0.2
Qualifications: nursing, teaching	0.9	1.4	3.1	0.6	1.0	1.7	1.1	-0.9	-1.5	1.3	0.9	1.1
Pain type(s) experienced in last month: Hip pain	0.9	1.1	2.4	-1.4	-1.2	-1.6	-1.1	0.3	1.0	-1.2	0.3	-0.6
Ever depressed for a whole week	0.9	1.1	3.0	1.0	0.7	-0.2	1.1	1.7	0.9	-0.6	-0.9	-1.6
Bipolar Disorder or Schizophrenia	0.8	1.9	5.2	0.8	-0.0	1.8	0.1	-1.8	-2.3	1.2	1.5	1.0
Intelligence (Savage-Jansen 2018)	0.8	2.5	5.7	-2.0	-2.2	-1.8	-2.4	0.3	0.3	-2.2	0.2	-0.1
Fed-up feelings	0.8	1.4	4.0	-0.6	-0.8	-0.7	-1.1	1.0	1.1	-0.7	-1.8	-2.0
Past tobacco smoking	0.8	1.5	3.8	-0.4	-0.5	0.9	-0.4	-1.6	-2.0	0.7	1.2	1.9
Heart attack	0.8	1.0	2.4	-1.2	-1.6	-1.0	-1.2	-0.3	0.3	-1.2	0.7	-0.6
Medication: Simvastatin	0.8	1.2	2.2	-1.3	-0.5	-1.5	-0.8	1.3	1.3	-1.4	-0.6	-0.7
Time employed in main current job	0.8	0.9	2.6	-1.3	-1.4	-0.9	-1.6	0.1	0.3	-1.0	0.1	-0.6
Number of live births	0.8	1.2	4.6	0.8	0.6	0.8	0.7	-1.0	-1.2	0.7	2.1	1.1
Length of working week for main job	0.8	0.9	1.7	-1.3	-1.0	-0.9	-1.0	0.7	0.9	-0.9	-0.8	-0.9
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	2.8	0.8	0.8	-0.3	1.0	1.5	1.4	-0.3	-1.7	-1.3
Medication: Paracetamol	0.8	1.4	3.3	0.1	-0.1	-1.2	-0.0	1.7	1.8	-1.1	-1.3	-1.4
Forced vital capacity (FVC), Best measure	0.8	2.8	5.1	-2.1	-1.4	-2.3	-1.6	0.9	1.8	-1.8	-1.8	-1.0
Health satisfaction	0.8	1.0	2.7	-0.7	-1.6	-0.6	-1.4	0.4	0.6	-0.7	-0.8	-1.4
Number of full sisters	0.8	1.0	1.9	0.6	1.0	-0.2	1.1	1.1	1.3	-0.0	-1.4	-1.2
Leg pain on walking	0.8	1.0	1.7	-0.4	-0.9	-1.3	-1.1	0.6	1.3	-1.1	-0.7	-1.0
Osteoporosis (self-reported)	0.8	1.0	3.0	0.1	1.7	0.5	1.7	0.5	-0.0	0.6	1.5	0.5
Osteoarthritis (self-reported)	0.8	1.0	1.5	-0.8	-1.0	-1.2	-1.0	0.9	1.2	-1.2	-0.6	-0.8
Smoking status: Current	0.8	1.3	4.6	2.1	1.4	0.2	1.4	0.4	1.0	0.7	-1.0	-0.5
Average weekly champagne plus white wine intake	0.8	1.1	2.0	-0.4	-0.7	-1.2	-0.6	1.2	1.2	-0.9	-1.2	-1.4
High cholesterol (Self-reported)	0.8	1.4	2.6	-1.6	-1.0	-1.5	-1.0	1.0	1.3	-1.3	-0.6	-0.9
Fractured/broken bones in last 5 years	0.8	1.0	3.3	0.2	0.0	-0.2	0.3	1.8	1.2	-0.6	-1.1	-1.7
Heart disease (siblings)	0.8	0.9	2.9	-0.5	-0.9	0.3	-0.7	-1.7	-1.1	0.5	1.4	0.8
Schizophrenia (2018)	0.7	1.4	2.6	-1.1	-1.5	0.4	-1.4	-1.6	-1.6	-0.1	1.0	0.8
Prostate Cancer	0.7	1.0	2.1	0.8	0.9	0.8	0.7	-1.1	-0.8	0.9	1.4	1.3
LDL Cholesterol	0.7	1.1	4.5	1.3	2.1	0.8	1.5	-0.1	0.0	0.9	0.3	0.4
Schizophrenia (2014)	0.7	1.5	4.3	-0.4	-1.2	1.1	-1.1	-1.7	-2.1	0.5	1.3	0.6
Chronotype (morning person)	0.7	1.7	3.1	1.5	1.0	1.4	1.4	-0.9	-1.2	1.4	1.8	0.7
Ever had hysterectomy (womb removed)	0.7	0.8	2.2	-0.3	0.3	-0.7	0.4	1.1	1.5	-0.6	-1.2	-0.9
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.4	-0.3	-0.5	-1.0	-0.3	0.8	1.3	-1.0	-0.0	-1.6
Diabetes (father)	0.7	0.8	1.9	0.7	-0.2	-0.4	-0.0	1.4	1.1	-0.6	-1.2	-1.4
Hayfever, allergic rhinitis or eczema	0.7	1.5	4.6	1.6	2.1	0.6	2.1	-0.5	0.1	1.1	0.7	0.6
Trunk fat mass	0.7	3.0	8.6	-2.2	-2.8	-1.2	-2.9	-1.2	-0.3	-1.2	0.2	0.6
Had menopause	0.7	0.9	2.0	1.0	1.4	0.4	1.1	-0.5	-0.3	0.4	1.4	1.0
Worrier / anxious feelings	0.7	1.3	4.0	-0.4	0.0	-0.9	-0.0	2.0	1.3	-1.0	-1.4	-1.5
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.2	2.9	-1.4	-1.7	-0.8	-1.5	-0.4	0.5	-0.6	-0.6	-1.2
Pulse wave reflection index	0.7	0.9	2.2	0.6	1.1	-0.2	0.9	1.0	1.2	0.2	-1.5	-0.8
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.3	0.8	1.0	-0.1	0.6	1.3	1.1	0.5	-1.5	-0.5
Worry too long after embarrassment	0.7	1.2	2.3	-1.0	-1.1	-1.4	-0.9	0.7	1.0	-1.5	-0.3	-1.4
Shortness of breath walking on level ground	0.7	0.8	1.8	-0.8	-1.0	-1.3	-0.8	-0.1	1.3	-0.5	-0.2	-1.0
Pulse rate, automated reading	0.7	2.4	5.5	-0.3	-0.6	0.7	-0.8	-2.3	-2.0	0.7	2.1	2.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.2	-1.3	-0.7	-1.8	-1.0	0.9	1.8	-0.9	-1.1	-0.9
Mood swings	0.7	1.3	2.7	-1.0	-1.2	-1.6	-1.4	0.7	1.1	-1.4	-0.6	-1.0
Heart attack/myocardial infarction (self-reported)	0.7	1.0	2.2	-1.3	-1.5	-1.1	-1.2	-0.3	0.3	-1.2	0.7	-0.4
Irritable Bowel Disease (IBD)	0.6	1.4	3.9	-0.1	0.4	0.9	0.6	-2.0	-1.0	1.4	1.7	1.4
HDL Cholesterol	0.6	1.0	2.2	1.1	1.4	0.6	1.5	-0.6	-0.2	1.3	0.5	0.6
Allergy or Eczema	0.6	1.6	4.8	1.2	2.2	1.0	2.0	-0.5	-0.5	1.2	1.0	0.8
Neuroticism	0.6	1.5	3.2	-0.5	-1.6	-1.0	-1.5	0.9	0.7	-1.2	-1.1	-1.8
Sensitivity / hurt feelings	0.6	1.1	2.4	-0.6	-1.1	-1.0	-0.8	1.1	0.9	-1.2	-0.4	-1.5
Relative age of first facial hair	0.6	1.2	4.1	-0.6	-0.0	-0.1	-0.2	-2.0	-0.5	0.5	1.6	1.8
Angina	0.6	0.8	2.5	-0.3	-0.5	-0.9	-0.1	1.0	1.1	-1.0	-0.3	-1.6
Trunk fat percentage	0.6	2.6	7.4	-2.1	-2.7	-1.1	-2.7	-1.0	-0.2	-1.2	0.0	0.3
Current tobacco smoking	0.6	1.0	3.5	1.9	1.2	0.1	1.2	0.3	1.0	0.6	-1.0	-0.5
Chronic bronchitis/emphysema (father)	0.6	0.7	2.1	1.0	1.5	0.1	1.4	-0.2	0.5	0.5	0.4	0.3
Forced vital capacity (FVC)	0.6	2.2	3.7	-1.9	-0.8	-1.7	-1.0	1.6	1.6	-1.5	-1.9	-1.1
Allergy	0.6	1.3	4.4	-1.5	-2.0	-0.6	-2.1	-0.5	-0.5	-0.7	0.1	0.4
Happiness	0.6	0.7	1.9	1.1	0.2	1.4	0.5	-0.0	-1.4	0.4	0.9	0.1
Pulse wave Arterial Stiffness index	0.6	0.8	2.6	1.0	1.6	0.8	1.4	0.3	0.1	0.7	-0.1	-0.0
Exposure to tobacco smoke outside home	0.6	0.8	1.9	1.4	1.2	0.4	1.2	1.0	0.6	0.1	-0.5	-1.0
Pulse wave peak to peak time	0.6	0.8	2.4	-1.0	-1.5	-0.9	-1.4	-0.5	-0.0	-0.7	0.2	0.1
Angina (self-reported)	0.6	0.8	2.5	-0.5	-0.6	-0.9	-0.2	1.0	1.0	-1.1	-0.3	-1.6
Whole body fat mass	0.6	2.4	7.4	-1.9	-2.7	-0.9	-2.7	-1.2	-0.5	-1.0	0.4	0.5
Had major operations	0.6	0.7	2.2	-0.8	-1.5	-0.7	-1.3	-0.6	-0.2	-0.6	0.6	0.2
Medication: Aspirin	0.6	0.8	1.6	-1.3	-0.5	-1.1	-0.7	0.8	1.2	-0.9	-0.2	-1.1
Back pain experienced in last month	0.6	0.8	1.6	-0.8	-0.7	-0.8	-0.6	1.3	0.9	-0.8	-1.1	-1.0
Medication: Aspirin	0.6	0.7	1.4	-1.2	-0.5	-1.1	-0.7	0.7	1.0	-1.0	0.2	-0.9
Financial situation satisfaction	0.6	0.7	1.6	-0.4	-0.8	-0.9	-0.6	0.9	0.8	-1.3	0.1	-1.2
Medication: Atorvastatin	0.6	0.7	2.1	-0.5	-0.2	-1.1	0.2	0.9	1.4	-0.9	-0.2	-1.1
Neuroticism (Nagel 2018)	0.5	1.1	3.0	-0.4	-1.1	-0.8	-1.3	0.7	0.8	-0.9	-1.1	-1.7
Alzheimer’s Disease (in mother)	0.5	0.5	1.2	1.1	0.9	1.0	0.5	0.1	-0.9	0.6	0.2	0.5
Alzheimer’s Disease (in father)	0.5	0.5	1.3	-0.2	1.1	0.6	1.1	-0.2	-0.3	0.5	1.1	0.5
Ovarian Cancer	0.5	0.7	2.5	0.1	0.0	0.3	0.2	-1.6	-0.8	0.6	1.4	0.8
Mean Putamen Volume	0.5	0.6	1.9	0.2	0.3	0.8	-0.0	-0.6	-1.2	0.5	0.6	1.4
Ulcerative Colitis	0.5	0.7	2.3	-1.5	-0.8	-0.3	-0.9	-1.3	-0.2	0.0	0.4	0.6
Waist Hip Ratio (WHR)	0.5	2.1	4.4	1.6	2.1	1.6	1.8	-0.3	-0.9	1.9	-0.1	1.2
Hearing difficulty/problems: Yes	0.5	0.7	1.4	0.7	1.0	0.6	1.0	-0.8	-0.6	0.8	1.2	0.4
Medication for hormone replacement therapy	0.5	0.6	1.3	-0.8	-0.6	-0.5	-0.3	0.8	0.8	-0.4	-1.1	-1.2
Medication: Metformin	0.5	0.7	2.0	-0.2	-1.4	-0.8	-1.1	0.4	0.5	-1.1	-0.2	-0.9
Leg fat-free mass (left)	0.5	2.4	7.1	-1.9	-2.5	-1.5	-2.7	-0.7	0.4	-1.3	-0.2	0.0
Hand grip strength (right)	0.5	1.3	2.8	-1.5	-0.6	-1.7	-0.9	1.1	1.3	-1.5	-0.6	-0.1
Relative age voice broke	0.5	0.7	2.1	0.2	1.0	0.3	0.9	-0.7	-0.3	0.7	1.4	1.0
Sitting height	0.5	3.2	6.7	-2.1	-2.6	-1.8	-2.5	0.9	0.7	-2.1	-1.2	-0.9
Leg predicted mass (left)	0.5	2.5	7.5	-2.0	-2.6	-1.5	-2.7	-0.7	0.3	-1.3	-0.3	0.0
Pain all over the body in last month	0.5	0.6	1.3	1.1	0.3	0.9	0.8	-0.9	-0.8	0.6	0.6	0.2
Weight	0.5	2.5	7.8	-1.9	-2.6	-1.1	-2.8	-1.2	-0.3	-1.1	0.5	0.7
Hip circumference	0.5	2.2	5.8	-1.8	-2.3	-0.9	-2.4	-1.5	-0.4	-1.0	0.7	0.8
Alcohol intake versus 10 years previously	0.5	0.8	2.0	1.1	-0.2	0.9	-0.0	-1.4	-1.0	0.8	1.1	0.5
Hair/balding pattern: Pattern 3	0.5	0.8	3.1	-0.2	-1.2	-0.4	-0.9	0.0	0.6	-0.3	-1.8	-1.0
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.2	0.8	1.1	0.9	1.1	0.1	-0.4	0.9	0.4	0.4
Arm fat mass (right)	0.5	2.2	7.1	-1.7	-2.6	-0.8	-2.7	-1.1	-0.5	-0.9	0.3	0.4
Tense / ‘highly strung’	0.5	0.8	2.3	0.1	-0.5	0.0	-0.1	1.4	0.4	-0.7	-1.3	-1.5
Hair/balding pattern: Pattern 4	0.5	1.3	3.6	-0.3	0.8	-1.5	0.3	1.5	1.9	-1.0	-1.0	-0.6
Medication: Amlodipine	0.5	0.6	2.2	-0.6	-0.3	-1.2	-0.1	0.4	1.5	-0.8	-0.1	-0.9
Body fat percentage	0.5	2.0	5.8	-1.7	-2.4	-0.6	-2.4	-1.3	-0.7	-0.8	0.5	0.6
Medication: Allopurinol	0.5	0.7	2.0	-1.4	-0.7	-0.9	-1.4	-0.1	0.2	-0.5	-0.1	0.6
Leg fat mass (right)	0.5	1.8	5.0	-1.3	-2.2	-0.1	-2.2	-1.5	-1.1	-0.4	0.9	0.8
Alcohol intake frequency.	0.5	1.3	2.1	-1.0	-1.4	-0.9	-1.4	1.0	0.8	-1.3	-1.0	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.6	0.7	1.3	0.2	1.3	-0.2	0.2	0.7	-0.0	0.8
Leg fat-free mass (right)	0.5	2.8	8.1	-2.1	-2.7	-1.7	-2.9	-0.5	0.5	-1.4	-0.4	-0.1
Leg predicted mass (right)	0.5	2.6	7.9	-2.0	-2.6	-1.6	-2.8	-0.6	0.4	-1.3	-0.3	-0.0
Arm fat mass (left)	0.5	2.0	6.3	-1.6	-2.4	-0.8	-2.5	-1.1	-0.5	-0.9	0.3	0.5
Ever taken oral contraceptive pill	0.5	0.5	1.8	-0.6	-0.1	0.2	-0.0	-0.8	-1.1	0.2	1.3	1.0
Medication: Paracetamol	0.5	0.7	1.8	-0.2	-0.4	-1.0	-0.2	1.1	1.3	-0.9	-0.8	-1.1
Leg fat mass (left)	0.5	2.0	5.3	-1.4	-2.2	-0.2	-2.3	-1.6	-1.2	-0.3	1.1	0.9
Reaction Time	0.4	0.7	3.3	0.5	0.4	0.6	0.4	-0.7	-0.9	0.5	1.8	0.9
Breast Cancer	0.4	0.9	2.0	0.9	-0.1	-0.8	-0.1	1.4	1.1	-0.8	-1.0	-1.3
Body Mass Index (BMI) (2010)	0.4	0.6	1.7	-1.0	-1.1	-0.5	-1.3	-0.7	0.1	-0.3	-0.4	-0.1
Systolic Blood Pressure	0.4	2.2	4.4	-0.8	-0.4	-1.5	-0.2	2.1	2.1	-1.4	-1.3	-2.1
Hair/balding pattern: Pattern 2	0.4	0.5	2.0	-0.5	-0.2	0.7	0.0	-0.5	-1.0	0.2	1.4	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	1.4	1.0	1.1	0.8	1.0	-0.5	-0.8	1.2	0.6	0.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.2	0.1	0.4	-0.8	0.5	1.0	1.1	-0.6	-0.5	-0.8
Illnesses of siblings	0.4	0.5	1.2	1.1	0.6	0.9	0.6	-0.5	-0.7	0.8	-0.3	0.6
Falls in the last year	0.4	0.5	1.5	0.9	1.2	0.5	1.1	0.6	0.1	0.4	0.3	-0.1
Mouth/teeth dental problems: Dentures	0.4	0.7	2.0	-0.7	-1.3	-0.6	-0.7	0.0	0.7	-0.9	-0.0	-1.4
Prospective memory result	0.4	0.4	1.3	0.3	-0.0	0.8	0.4	-1.1	-0.7	0.8	0.6	0.5
Illnesses of mother	0.4	0.6	1.5	-0.3	0.3	0.4	0.3	-1.0	-0.7	0.5	1.2	1.2
Birth weight of first child	0.4	0.7	2.1	1.3	1.2	0.4	1.4	0.4	0.3	0.2	-0.6	-0.5
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.2	1.0	-1.1	0.2	-0.7	-1.1	-0.3	-0.1	-0.2	-0.3
Birth weight	0.4	0.9	3.1	1.8	0.7	0.4	0.5	-0.7	-0.8	0.3	1.3	0.9
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.4	0.8	1.2	0.5	1.0	0.1	0.3	0.7	0.0	-0.3
Leg fat percentage (right)	0.4	1.3	2.8	-0.9	-1.6	0.4	-1.7	-1.4	-1.3	-0.1	1.0	0.8
Arm fat-free mass (right)	0.4	2.0	6.0	-1.8	-2.2	-1.3	-2.4	-0.6	0.1	-1.2	0.2	0.2
Number of children fathered	0.4	0.4	1.2	-0.1	0.2	1.0	0.2	-0.1	-1.1	0.5	1.0	0.7
Age at first live birth	0.4	0.8	1.5	0.8	0.7	1.1	0.6	-1.2	-0.9	1.1	0.7	0.7
Medication: Omeprazole	0.4	0.5	1.1	0.4	1.1	0.3	0.9	1.0	0.6	0.3	-0.8	-0.6
Arm predicted mass (right)	0.4	1.8	5.5	-1.7	-2.1	-1.2	-2.4	-0.7	0.0	-1.2	0.3	0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.8	-0.3	-0.4	-0.7	-0.4	1.3	0.7	-0.7	-0.6	-0.7
Arm fat percentage (left)	0.4	1.5	4.8	-1.5	-2.1	-0.5	-2.2	-0.9	-0.5	-0.7	0.1	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	0.9	0.7	1.0	0.9	0.8	0.2	-0.6	0.7	0.7	-0.1
Eye problems/disorders: Cataract	0.4	0.4	1.2	0.7	1.1	0.5	0.8	-0.4	-0.2	0.9	0.0	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	2.4	0.4	0.6	0.3	0.6	-0.6	-0.4	0.3	1.5	0.3
Wears glasses or contact lenses	0.4	0.4	1.2	-1.0	0.2	-1.1	0.1	-0.1	1.0	-0.7	-0.1	-0.2
Commuting to job workplace: Public transport	0.4	0.5	2.0	-0.1	-0.1	-0.8	0.1	-1.0	0.5	-0.4	1.4	0.4
Basal metabolic rate	0.4	2.3	6.9	-1.9	-2.4	-1.4	-2.6	-0.7	0.2	-1.3	0.1	0.2
Leg fat percentage (left)	0.4	1.3	2.9	-0.9	-1.6	0.3	-1.7	-1.4	-1.3	-0.0	1.1	0.8
Number of operations (self-reported)	0.4	0.5	1.3	-0.7	-0.1	-0.9	-0.4	1.1	1.1	-0.7	-0.0	-0.5
Average weekly beer plus cider intake	0.4	0.5	2.1	-0.4	-0.4	-0.5	-0.7	0.6	0.6	-0.2	-1.4	-0.8
Unable to work because of sickness or disability	0.4	0.5	1.1	-0.3	-0.8	-0.7	-0.7	0.3	0.8	-0.6	-0.5	-1.0
Arm predicted mass (left)	0.4	2.1	6.7	-1.6	-2.4	-1.4	-2.6	-0.5	0.2	-1.3	0.0	-0.0
Bipolar Disorder (2011)	0.3	0.3	0.6	0.0	-0.8	0.2	-0.6	0.5	-0.7	-0.6	-0.1	-0.5
Crohns Disease (2012)	0.3	0.4	1.0	-0.6	-0.7	-1.0	-0.8	-0.4	0.4	-0.5	0.8	0.0
HbA1C	0.3	0.3	1.0	-0.1	-1.0	0.2	-0.4	0.4	-0.2	-0.3	-0.3	-1.0
Neuroticism (2016)	0.3	0.5	1.5	0.2	-0.6	0.5	-0.3	1.2	-0.2	-0.1	-0.7	-1.2
Primary Biliary Cirrhosis	0.3	0.4	1.6	0.6	-0.2	1.3	0.1	-0.1	-0.8	0.6	0.3	-0.4
Triglycerides	0.3	0.4	1.6	-0.3	-0.1	-0.3	0.0	0.6	0.9	-0.3	-1.3	-1.0
Blood White Count	0.3	2.5	8.8	-0.1	-0.3	0.8	-0.5	-3.0	-1.7	1.1	2.2	1.8
BMI	0.3	1.7	4.4	-1.6	-2.0	-0.3	-2.1	-1.3	-0.8	-0.4	1.1	0.9
Lung FVC	0.3	1.5	4.2	-0.5	1.0	-0.8	0.9	2.0	1.6	-1.0	-1.3	-1.3
Systolic blood pressure, automated reading	0.3	0.8	1.8	-1.3	-0.8	-1.2	-1.0	0.4	1.0	-1.0	-0.1	-0.7
Severe depression (siblings)	0.3	0.3	1.1	0.5	-0.2	1.0	-0.3	0.3	-1.0	0.4	0.1	-0.3
Medication: Atenolol	0.3	0.4	1.1	-0.4	-0.9	0.1	-0.6	0.6	-0.1	-0.6	-0.3	-1.0
Body mass index (BMI)	0.3	1.4	4.2	-1.0	-1.9	-0.1	-2.0	-1.1	-0.9	-0.4	0.8	0.7
Waist circumference	0.3	0.9	2.5	-1.0	-1.4	-0.1	-1.6	-1.1	-0.8	-0.2	0.6	0.9
Alcohol usually taken with meals	0.3	0.4	1.2	0.4	0.9	-0.4	0.8	1.1	0.7	-0.4	-0.1	-0.3
Nervous feelings	0.3	0.6	1.1	0.9	0.8	0.9	0.9	0.3	0.0	0.8	-0.8	-1.0
Hearing difficulty/problems with background noise	0.3	0.4	1.1	0.5	0.8	-0.7	0.9	-0.0	0.6	-0.1	1.1	-0.1
Financial difficulties in last 2 years	0.3	0.3	0.7	0.8	0.8	0.8	0.8	0.1	0.0	0.7	-0.1	-0.4
Mouth/teeth dental problems	0.3	0.5	1.5	-0.5	-0.4	0.2	-0.4	-1.0	-1.1	0.1	0.6	1.2
Arm fat percentage (right)	0.3	1.4	4.6	-1.3	-2.1	-0.5	-2.1	-0.9	-0.5	-0.7	0.2	0.2
Standing height	0.3	3.2	7.2	-2.4	-1.9	-2.7	-2.1	0.2	1.8	-2.0	-0.8	-0.3
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.3	-1.1	-0.6	-0.6	-0.7	-0.5	0.1	-0.4	0.7	0.5
Comparative body size at age 10	0.3	0.9	2.3	-1.4	-1.1	-1.1	-1.5	-0.2	0.2	-0.9	0.4	0.2
Medication: Blood pressure	0.3	0.6	1.1	0.7	1.0	0.6	0.8	-0.1	-0.6	0.7	1.0	0.8
Mean time to correctly identify matches	0.3	0.6	2.3	-0.5	-0.9	-0.2	-0.8	-0.5	-0.7	-0.7	1.5	0.5
Supplements: Vitamin C	0.3	0.3	0.6	-0.0	-0.4	-0.5	-0.4	0.8	0.6	-0.7	-0.8	-0.7
Illnesses of father: Heart disease	0.3	0.5	0.9	-0.7	-0.6	-0.3	-0.8	0.8	0.1	-0.8	-1.0	-0.4
Whole body fat-free mass	0.3	2.0	5.9	-1.7	-2.2	-1.4	-2.4	-0.6	0.3	-1.2	0.0	0.2
Ever had bowel cancer screening	0.3	0.3	1.1	0.5	1.0	-0.1	0.8	0.4	0.6	0.2	-0.2	0.4
Commuting to job workplace: Walk	0.3	0.3	0.9	-0.2	0.9	-0.0	0.8	0.2	-0.1	0.1	1.0	0.4
Mineral and other dietary supplements	0.3	0.4	1.5	0.6	0.0	0.4	0.1	-1.2	-0.4	0.9	0.7	0.6
Whole body water mass	0.3	1.7	5.2	-1.6	-2.1	-1.3	-2.3	-0.7	0.2	-1.1	0.2	0.3
Eye problems/disorders: Glaucoma	0.3	0.3	0.7	-0.4	-0.0	0.7	-0.2	-0.2	-0.9	0.7	0.6	0.6
Medication: Lisinopril	0.3	0.3	1.2	-0.1	0.0	0.4	0.1	-1.1	-0.5	0.8	0.6	0.7
Alcohol drinker status: Never	0.3	0.3	1.4	-0.0	0.5	0.3	0.7	1.2	0.3	-0.1	-0.4	-0.5
Arm fat-free mass (left)	0.3	1.7	5.7	-1.4	-2.2	-1.2	-2.4	-0.6	0.0	-1.2	0.3	0.3
Medication: Omeprazole (e.g. Zanprol)	0.3	0.3	0.9	0.2	1.0	0.5	0.8	0.7	0.1	0.5	-0.7	-0.0
Pain experienced in last month	0.3	0.5	1.4	0.0	-0.3	0.7	-0.6	-1.0	-1.2	0.4	0.5	0.9
Crohns Disease (2017)	0.2	0.4	1.6	0.1	0.3	0.4	0.5	-0.8	-0.3	0.8	1.3	0.5
Coronary Artery Disease (CAD)	0.2	0.3	0.7	0.4	0.8	0.8	0.5	0.5	-0.3	0.4	0.2	-0.3
Blood Eosinophil Count	0.2	1.4	3.5	-1.7	-1.8	-1.0	-1.9	-0.6	0.3	-1.0	-0.1	-0.3
Blood Red Count	0.2	1.8	4.9	1.1	0.7	0.4	0.9	2.2	1.2	-0.1	-2.0	-1.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.1	-0.0	1.0	-0.1	0.9	0.4	0.5	0.2	0.3	0.0
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.8	-1.3	-0.4	-0.6	-0.3	0.1	0.2	-0.5	0.1	0.0
Average weekly fortified wine intake	0.2	0.3	1.2	-0.6	0.4	0.2	0.5	-0.3	-0.4	-0.0	1.1	0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	0.9	0.4	0.3	0.8	0.3	-0.4	-1.0	0.8	0.7	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	-0.1	-0.8	-0.2	-0.9	0.1	0.2	-0.0	-0.8	-1.0
Trunk fat-free mass	0.2	1.0	3.0	-1.2	-1.5	-1.0	-1.7	-0.7	0.0	-0.8	0.5	0.5
Father’s age at death	0.2	0.3	1.1	0.1	0.6	0.3	1.0	-0.2	-0.1	0.5	0.5	0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.2	0.4	0.9	-0.2	0.9	1.1	0.6	-0.3	-0.5	-0.5
Trunk predicted mass	0.2	1.0	3.1	-1.2	-1.5	-1.0	-1.8	-0.7	0.0	-0.8	0.4	0.5
Gout (self-reported)	0.2	0.2	0.6	-0.3	0.3	0.7	-0.2	-0.3	-0.6	0.8	0.1	0.7
Wheeze or whistling in the chest in last year	0.2	0.4	0.8	0.6	0.5	0.1	0.6	0.7	0.6	0.4	-0.6	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.5	-0.6	-0.7	-0.1	-0.2	-0.1	-0.1	-0.4	0.5	-0.6
Qualifications: College or University degree	0.2	0.8	1.4	0.9	1.2	0.8	1.2	-0.8	-0.4	1.1	0.3	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	0.8	0.2	-0.2	-0.5	-0.3	0.2	0.6	-0.0	-0.9	-0.5
Comparative height size at age 10	0.2	1.4	3.0	-1.4	-0.7	-1.7	-0.8	0.3	1.6	-1.3	-1.1	-0.7
Chest pain or discomfort	0.2	0.3	1.1	0.1	-0.6	0.1	-0.3	-0.1	0.4	0.2	-1.0	-1.0
Guilty feelings	0.2	0.3	0.7	-0.1	-0.5	-0.8	-0.5	0.5	0.4	-0.8	-0.7	-0.4
Hearing aid user	0.2	0.3	0.7	0.1	0.8	-0.3	0.8	0.2	0.7	0.1	0.4	-0.2
Medication: Blood pressure	0.2	0.3	1.1	0.4	0.1	0.6	0.4	-0.7	-0.5	0.4	1.1	0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.2	-0.9	0.1	-0.3	-0.0	1.1	0.2	-0.7	-0.4	-0.2
Diastolic blood pressure, automated reading	0.2	0.7	2.3	-0.9	-1.2	-0.4	-1.5	-1.0	-0.4	-0.1	0.2	0.6
Cholesterol lowering medication	0.2	0.4	0.8	-0.7	-0.4	-0.6	-0.1	0.6	0.9	-0.6	-0.4	-0.6
Supplements: Calcium	0.2	0.2	0.6	0.4	0.6	0.4	0.3	-0.4	-0.4	0.5	0.8	0.5
Worry (Nagel 2018)	0.1	0.3	1.2	0.5	-0.3	0.1	-0.0	0.6	0.2	-0.1	-0.5	-1.1
Alzheimer’s Disease (including proxy)	0.1	0.2	0.4	0.4	0.6	0.6	0.4	0.5	-0.4	0.2	-0.0	-0.1
Major Depression (MDD)	0.1	0.1	0.3	0.2	-0.5	-0.1	-0.4	0.2	-0.4	-0.4	0.6	-0.1
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.4	0.1	-0.2	-0.6	-0.4	0.1	0.6	-0.2	-0.0	-0.4
Heel T-Score	0.1	0.7	2.2	0.4	0.5	1.2	0.5	0.1	-1.5	0.6	0.8	0.9
Height	0.1	2.2	5.4	-1.2	-2.3	-1.9	-2.3	-1.1	0.6	-1.5	0.1	0.5
Cardiovascular Disease	0.1	0.2	0.8	-0.2	-0.4	-0.2	-0.0	0.5	0.5	-0.2	0.0	-0.9
Lung FEV1/FVC ratio	0.1	0.7	1.7	0.5	-0.9	-0.7	-0.9	-0.2	-0.4	-1.3	1.2	0.5
Tanning	0.1	1.7	2.0	1.4	1.4	1.4	1.3	-1.3	-1.3	1.4	1.1	1.3
Diabetes (mother)	0.1	0.1	0.6	0.8	-0.5	0.1	-0.3	-0.0	-0.2	-0.1	-0.1	-0.2
Pack years adult smoking proportion	0.1	0.1	0.4	-0.0	-0.2	-0.0	-0.1	-0.6	0.2	0.4	-0.6	-0.3
Impedance of leg (right)	0.1	0.4	0.8	0.4	0.6	0.1	0.8	0.6	0.5	0.1	-0.9	-0.7
Maternal smoking around birth	0.1	0.1	0.4	-0.3	-0.2	-0.6	-0.3	0.1	0.5	-0.5	-0.2	-0.0
High blood pressure	0.1	0.3	1.2	0.3	0.6	-0.1	0.6	0.5	0.4	-0.1	1.1	-0.1
Multivitamins +/- minerals	0.1	0.1	0.2	-0.1	-0.3	0.3	-0.3	0.1	-0.4	-0.2	-0.5	-0.2
Supplements: Glucosamine	0.1	0.1	0.3	0.1	0.1	0.0	0.3	-0.3	-0.2	-0.1	0.6	0.4
Impedance of leg (left)	0.1	0.3	0.6	0.5	0.5	0.1	0.8	0.5	0.3	0.2	-0.7	-0.5
Fluid intelligence score	0.1	0.1	0.5	-0.3	-0.4	-0.3	-0.5	-0.2	-0.1	-0.7	0.3	-0.1
Impedance of arm (right)	0.1	0.7	2.4	0.3	0.6	-0.5	0.8	0.6	1.2	0.0	-1.5	-0.8
Impedance of arm (left)	0.1	0.6	2.7	-0.3	0.2	-0.5	0.3	0.6	1.1	-0.1	-1.6	-0.6
High blood pressure (siblings)	0.1	0.2	1.0	-0.2	0.3	0.2	0.2	-0.3	-0.2	0.4	1.0	0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	0.3	0.0	0.1	-0.2	-0.0	-0.1	0.5	-0.6	-0.2
Suffer from ‘nerves’	0.1	0.2	0.9	0.6	-0.5	0.3	-0.1	-0.2	-0.2	0.1	-0.4	-1.0
Family relationship satisfaction	0.1	0.1	0.4	0.2	0.3	0.6	0.2	-0.0	-0.4	0.3	-0.6	-0.0
Hypertension (Self-reported)	0.1	0.3	1.3	0.5	0.7	-0.0	0.7	0.0	0.2	0.2	1.2	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.3	0.3	0.3	0.2	0.6	0.3	0.0	-0.0	0.1	0.0
Long-standing illness, disability or infirmity	0.1	0.2	0.4	-0.5	-0.6	-0.4	-0.6	0.0	0.5	-0.3	-0.4	-0.4
Friendships satisfaction	0.1	0.1	0.2	0.3	-0.1	-0.1	-0.4	-0.3	-0.3	-0.2	0.1	0.2
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.5	-0.1	0.1	-0.4	-0.1	0.7	0.6	-0.5	-0.4	-0.2
Medication for cholesterol	0.1	0.1	0.2	0.2	0.0	0.1	-0.2	-0.5	-0.4	0.1	0.2	0.5
Breast cancer (self-reported)	0.1	0.2	0.6	0.6	0.4	0.5	0.8	0.1	-0.0	-0.0	-0.1	-0.2
Illnesses of father: None of the above (group 1)	0.1	0.2	0.3	0.4	0.3	0.3	0.4	-0.3	-0.3	0.5	0.5	0.5
Medication: Bendroflumethiazide	0.1	0.1	0.7	0.2	0.4	-0.0	0.1	0.8	0.1	-0.2	-0.4	-0.1
Irritability	0.1	0.2	0.5	0.7	0.5	0.7	0.3	0.0	-0.4	0.6	-0.5	-0.3
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.7	-0.5	-0.4	0.1	-0.5	-0.2	-0.2	0.1	-1.3	0.1
Basal cell carcinoma (self-reported)	0.1	0.1	0.2	0.3	0.3	0.0	0.2	0.2	0.2	-0.1	0.4	-0.5
Pack years of smoking	0.1	0.2	1.3	-0.1	-0.1	0.2	-0.0	-1.1	-0.3	0.6	-0.1	0.3
Impedance of whole body	0.1	0.7	2.4	-0.1	0.1	-0.7	0.3	0.9	1.2	-0.4	-1.6	-1.0
Hair Pigment	0.0	0.8	3.7	1.9	1.2	0.5	1.2	0.6	0.3	0.5	0.1	-0.2
Townsend deprivation index at recruitment	0.0	0.0	0.1	0.2	-0.1	0.1	-0.0	0.1	0.1	0.0	-0.3	-0.3
Medication for cholesterol, blood pressure or diabetes	0.0	0.1	0.3	0.1	-0.2	0.3	0.0	-0.5	-0.2	0.1	-0.2	-0.0
Eye problems/disorders: None of the above	0.0	0.1	0.2	0.3	-0.0	0.1	-0.0	-0.4	-0.3	0.1	-0.1	0.3

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