Best TWAS P=2.32e-10 · Best GWAS P=7.9e-12 conditioned to 0.00771
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | OSMR | 0.12 | 0.06 | lasso | 3 | 0.05 | 4.8e-05 | -6.5 | 6.3 | 2.3e-10 | -0.88 | 0.01 | 0.98 | TRUE |
2 | GTEx | Cells Transformed fibroblasts | OSMR | 0.15 | 0.01 | enet | 16 | 0.06 | 3.1e-05 | -6.7 | 5.8 | 5.9e-09 | -0.72 | 0.01 | 0.98 | FALSE |