[Hub]/) : Traits : Blood Platelet Count :

chr5:71,557,313-73,083,183

Best TWAS P=1.21e-29 · Best GWAS P=5.47e-35 conditioned to 0.00134

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland FCHO2 0.11 0.03 lasso 3 0.01 1.2e-01 -5.2 -7.0 3.3e-12 0.56 0.06 0.66 FALSE
2 GTEx Artery Aorta FCHO2 0.07 0.04 lasso 2 0.03 5.2e-03 -5.4 -6.0 2.6e-09 0.48 0.17 0.35 FALSE
3 GTEx Artery Tibial FCHO2 0.14 0.03 enet 59 0.02 5.9e-03 -7.5 -8.8 1.0e-18 0.49 0.28 0.40 FALSE
4 GTEx Cells EBV-transformed lymphocytes FCHO2 0.28 0.15 enet 21 0.05 8.7e-03 -5.1 -6.6 3.9e-11 0.52 0.16 0.35 FALSE
5 GTEx Cells Transformed fibroblasts FCHO2 0.10 0.04 lasso 10 0.05 6.0e-05 -5.4 -5.8 7.3e-09 0.40 0.63 0.28 FALSE
6 GTEx Esophagus Gastroesophageal Junction FCHO2 0.16 -0.01 enet 24 -0.01 7.5e-01 -7.5 -9.8 1.6e-22 0.54 0.05 0.43 TRUE
7 GTEx Esophagus Mucosa FCHO2 0.15 0.07 lasso 2 0.09 1.1e-06 -5.4 5.4 5.7e-08 -0.42 0.98 0.00 FALSE
8 GTEx Nerve Tibial FCHO2 0.10 0.08 enet 17 0.05 3.4e-04 -5.2 -5.8 7.3e-09 0.56 0.71 0.20 FALSE
9 GTEx Pancreas FCHO2 0.11 0.04 enet 7 0.03 1.8e-02 -7.7 -8.4 4.3e-17 0.56 0.23 0.16 FALSE
10 GTEx Skin Sun Exposed Lower leg FCHO2 0.06 0.03 enet 20 0.03 2.6e-03 -5.1 -8.3 8.4e-17 0.56 0.25 0.21 FALSE
11 GTEx Testis FCHO2 0.13 0.06 lasso 8 0.06 1.4e-03 -11.6 -11.3 1.2e-29 0.93 0.07 0.82 TRUE
12 The Cancer Genome Atlas Breast Invasive Carcinoma FCHO2 0.05 0.04 blup 84 0.04 1.9e-09 -5.1 -7.1 1.0e-12 0.46 1.00 0.00 FALSE
13 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FCHO2 0.08 0.00 blup 84 0.03 1.0e-02 -5.0 -6.8 7.2e-12 0.50 0.04 0.18 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma FCHO2 0.05 0.03 blup 84 0.01 1.2e-02 -5.4 -5.8 6.4e-09 0.41 0.10 0.11 FALSE