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chr5:71,557,313-73,083,183

Best TWAS P=1.21e-29 · Best GWAS P=5.47e-35 conditioned to 0.00134

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Testis	FCHO2	0.13	0.06	lasso	8	0.06	1.4e-03	-11.6	-11.3	1.2e-29	0.93	0.07	0.82	TRUE
6	GTEx	Esophagus Gastroesophageal Junction	FCHO2	0.16	-0.01	enet	24	-0.01	7.5e-01	-7.5	-9.8	1.6e-22	0.54	0.05	0.43	TRUE
3	GTEx	Artery Tibial	FCHO2	0.14	0.03	enet	59	0.02	5.9e-03	-7.5	-8.8	1.0e-18	0.49	0.28	0.40	FALSE
9	GTEx	Pancreas	FCHO2	0.11	0.04	enet	7	0.03	1.8e-02	-7.7	-8.4	4.3e-17	0.56	0.23	0.16	FALSE
10	GTEx	Skin Sun Exposed Lower leg	FCHO2	0.06	0.03	enet	20	0.03	2.6e-03	-5.1	-8.3	8.4e-17	0.56	0.25	0.21	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	FCHO2	0.05	0.04	blup	84	0.04	1.9e-09	-5.1	-7.1	1.0e-12	0.46	1.00	0.00	FALSE
1	GTEx	Adrenal Gland	FCHO2	0.11	0.03	lasso	3	0.01	1.2e-01	-5.2	-7.0	3.3e-12	0.56	0.06	0.66	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FCHO2	0.08	0.00	blup	84	0.03	1.0e-02	-5.0	-6.8	7.2e-12	0.50	0.04	0.18	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	FCHO2	0.28	0.15	enet	21	0.05	8.7e-03	-5.1	-6.6	3.9e-11	0.52	0.16	0.35	FALSE
2	GTEx	Artery Aorta	FCHO2	0.07	0.04	lasso	2	0.03	5.2e-03	-5.4	-6.0	2.6e-09	0.48	0.17	0.35	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	FCHO2	0.05	0.03	blup	84	0.01	1.2e-02	-5.4	-5.8	6.4e-09	0.41	0.10	0.11	FALSE
5	GTEx	Cells Transformed fibroblasts	FCHO2	0.10	0.04	lasso	10	0.05	6.0e-05	-5.4	-5.8	7.3e-09	0.40	0.63	0.28	FALSE
8	GTEx	Nerve Tibial	FCHO2	0.10	0.08	enet	17	0.05	3.4e-04	-5.2	-5.8	7.3e-09	0.56	0.71	0.20	FALSE
7	GTEx	Esophagus Mucosa	FCHO2	0.15	0.07	lasso	2	0.09	1.1e-06	-5.4	5.4	5.7e-08	-0.42	0.98	0.00	FALSE