Hub : Genes

FCHO2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0850 0.0290 2.1e-05 0.085 NA 0.098 NA 0.102 1.9e-07 NA 2.3e-08 NA 1.1e-08
2 GTEx Adipose Visceral Omentum 0.2710 0.0830 1.4e-05 0.097 NA 0.047 NA 0.057 9.8e-06 NA 1.8e-03 NA 6.2e-04
3 GTEx Adrenal Gland 0.1137 0.0531 9.9e-03 0.029 NA 0.007 NA 0.012 3.3e-02 NA 1.7e-01 NA 1.2e-01
4 GTEx Artery Aorta 0.0690 0.0320 8.9e-03 0.035 NA 0.016 NA 0.035 4.8e-03 NA 4.1e-02 NA 5.2e-03
5 GTEx Artery Tibial 0.1372 0.0551 2.2e-04 0.030 NA 0.023 NA 0.014 2.0e-03 NA 5.9e-03 NA 2.5e-02
6 GTEx Cells EBV-transformed lymphocytes 0.2750 0.0950 4.1e-04 0.147 NA 0.052 NA 0.035 1.6e-05 NA 8.7e-03 NA 2.6e-02
7 GTEx Cells Transformed fibroblasts 0.0960 0.0340 2.6e-05 0.043 NA 0.043 NA 0.055 3.7e-04 NA 3.4e-04 NA 6.0e-05
8 GTEx Esophagus Gastroesophageal Junction 0.1620 0.0750 8.6e-03 -0.008 NA -0.007 NA -0.008 9.2e-01 NA 7.5e-01 NA 9.0e-01
9 GTEx Esophagus Mucosa 0.1450 0.0510 2.0e-05 0.074 NA 0.063 NA 0.092 1.1e-05 NA 5.2e-05 NA 1.1e-06
10 GTEx Lung 0.2030 0.0610 2.7e-05 0.080 NA 0.069 NA 0.058 1.0e-06 NA 5.6e-06 NA 3.3e-05
11 GTEx Nerve Tibial 0.1025 0.0374 8.9e-05 0.078 NA 0.046 NA 0.033 3.4e-06 NA 3.4e-04 NA 2.1e-03
12 GTEx Pancreas 0.1140 0.0460 2.7e-03 0.043 NA 0.031 NA 0.024 6.8e-03 NA 1.7e-02 NA 3.3e-02
13 GTEx Skin Sun Exposed Lower leg 0.0600 0.0270 4.9e-03 0.032 NA 0.027 NA 0.010 1.1e-03 NA 2.6e-03 NA 4.6e-02
14 GTEx Testis 0.1320 0.0490 5.2e-04 0.062 NA 0.035 NA 0.058 1.0e-03 NA 1.1e-02 NA 1.4e-03
15 METSIM Adipose 0.0639 0.0201 2.3e-08 0.075 0.065 0.075 0.069 0.076 2.2e-11 4.6e-10 2.6e-11 1.3e-10 1.9e-11
16 NTR Blood 0.0420 0.0126 3.3e-09 0.032 0.027 0.028 0.027 0.035 1.4e-10 4.3e-09 2.0e-09 2.5e-09 2.4e-11
17 YFS Blood 0.2253 0.0352 0.0e+00 0.244 0.275 0.292 0.292 0.293 4.7e-79 2.7e-90 9.0e-97 8.9e-97 2.8e-97
18 TCGA Breast Invasive Carcinoma 0.0529 0.0247 1.2e-07 0.042 0.044 0.037 NA 0.041 4.3e-09 1.9e-09 3.6e-08 NA 6.8e-09
19 TCGA Colon Adenocarcinoma 0.1040 0.0510 1.4e-04 0.082 0.076 0.075 NA 0.060 1.8e-05 3.6e-05 4.0e-05 NA 2.4e-04
20 TCGA Kidney Renal Papillary Cell Carcinoma 0.0780 0.0430 6.1e-03 0.002 0.027 0.012 NA 0.016 2.3e-01 1.0e-02 6.5e-02 NA 3.7e-02
21 TCGA Brain Lower Grade Glioma 0.0486 0.0290 1.6e-04 0.043 0.024 0.021 NA 0.033 1.1e-05 8.0e-04 1.8e-03 NA 9.9e-05
22 TCGA Rectum Adenocarcinoma 0.3170 0.1360 1.0e-05 0.161 0.212 0.125 NA 0.204 1.3e-04 1.0e-05 7.5e-04 NA 1.6e-05
23 TCGA Soft Tissue Sarcoma 0.0580 0.0330 8.2e-04 0.035 0.047 0.039 NA 0.036 3.6e-03 8.9e-04 2.3e-03 NA 3.1e-03
24 TCGA Thyroid Carcinoma 0.0510 0.0330 4.1e-03 0.032 0.015 0.007 NA 0.012 3.7e-04 1.2e-02 6.6e-02 NA 2.0e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bipolar Disorder (2018) 2.1 3.4 6.4 -0.9 -1.6 -1.2 -1.7 -2.1 -1.1 -2.2 -2.3 1.9 0.6 -1.7 -2.5 -1.2 1.1 -2.0 -2.2 -1.8 -2.0 -1.6 -2.2 -1.9 -2.4 -2.5 -1.2
Bipolar Disorder or Schizophrenia 1.0 2.5 5.3 -0.7 -0.9 -1.1 -1.5 -0.7 -1.5 -1.8 -1.3 1.7 1.9 -1.3 -2.3 -1.1 0.6 -2.0 -1.9 -1.7 -1.6 -1.6 -2.1 -1.8 -2.0 -2.3 -0.7
Depressed Affect (Nagel 2018) 1.0 2.2 7.3 -1.7 -1.0 -1.9 -1.6 -1.2 -2.0 -0.4 -2.0 1.3 0.3 -1.6 -0.3 -2.4 -2.7 -1.2 -1.3 -1.4 -1.4 -1.5 -0.7 -1.1 0.2 -0.3 -2.1
Depression (Nagel 2018) 0.2 0.4 1.9 -0.2 -0.3 -0.3 -0.5 -1.0 -0.7 0.2 0.1 0.5 -0.8 -0.6 -0.4 -0.8 -1.0 -0.5 -1.4 -1.0 -0.3 -0.1 -0.3 -0.3 0.3 0.1 -0.4
Intelligence (Savage-Jansen 2018) 0.6 2.0 7.1 2.7 0.7 1.3 1.6 -2.1 1.4 1.0 1.8 -1.3 -1.3 -0.3 -1.6 1.4 -0.6 1.0 0.9 0.6 1.2 0.6 -0.7 1.3 1.0 1.8 2.5
Neuroticism (Nagel 2018) 2.4 5.5 14.2 -1.8 -2.1 -2.7 -2.5 -2.5 -2.6 -1.1 -2.6 2.4 -1.7 -3.0 -1.9 -3.8 -3.3 -2.3 -2.1 -2.0 -2.3 -2.7 -2.7 -2.0 -0.8 -1.0 -2.5
Schizophrenia (2018) 0.3 0.5 3.6 -0.2 0.2 -0.4 -0.6 0.7 -1.1 -0.6 0.1 0.7 1.9 -0.2 -0.9 -0.5 -0.1 -0.9 -0.7 -0.7 -0.5 -0.8 -1.0 -0.8 -0.6 -0.9 0.0
Schizophrenia vs Biploar Disorder 1.1 1.5 4.5 1.4 0.0 0.7 1.1 0.8 1.4 1.9 0.9 -1.2 -0.4 0.8 0.9 0.1 -2.0 1.1 1.3 1.1 0.9 0.7 -0.4 1.2 2.1 1.8 1.6
Worry (Nagel 2018) 2.0 4.1 11.1 -1.2 -2.2 -2.0 -1.9 -2.0 -1.7 -0.6 -1.9 2.0 -2.0 -2.8 -2.0 -3.3 -1.6 -1.9 -1.6 -1.7 -2.1 -2.5 -3.2 -1.8 -1.5 -1.3 -1.8
Alzheimer’s Disease (in mother) 0.8 1.0 2.6 -1.3 -1.2 -1.3 -1.3 0.9 -0.4 -0.7 -0.3 1.2 -0.1 -0.9 -0.3 -0.3 0.4 -1.1 -0.9 -0.9 -1.6 -1.1 -0.6 -1.3 -1.1 -1.4 -1.1
Alzheimer’s Disease (in father) 1.5 1.6 3.9 -1.5 -1.8 -1.4 -1.3 -0.4 -0.7 -1.1 -1.2 1.3 -1.3 -1.5 -0.7 -0.8 0.0 -1.6 -1.4 -1.5 -1.3 -2.0 -1.1 -1.4 -1.4 -1.8 -0.2
Alzheimer’s Disease (including proxy) 1.9 2.8 6.0 -1.9 -2.4 -1.9 -1.7 0.9 -1.0 -0.9 -0.7 1.8 -1.4 -1.8 -0.4 -0.9 0.5 -2.1 -1.8 -1.6 -2.1 -2.4 -1.6 -1.9 -2.1 -2.4 -0.8
Crohns Disease (2017) 0.3 0.6 3.4 0.4 -0.7 -0.3 -0.3 0.5 -0.2 -1.0 0.2 0.6 0.6 -0.0 -1.7 -0.1 1.3 -0.7 0.2 0.0 -0.5 -0.3 -1.9 -0.5 -1.1 -1.0 0.7
Irritable Bowel Disease (IBD) 0.4 0.9 6.1 0.6 -0.8 -0.6 -0.5 -1.2 -0.2 -1.2 -0.7 0.8 -0.1 -0.8 -2.3 -0.9 -0.0 -1.1 -0.3 -0.4 -0.4 -0.5 -2.5 -0.6 -0.9 -0.7 0.4
Ulcerative Colitis (UC) 0.4 0.8 3.5 0.7 -0.3 -0.6 -0.4 -1.8 -0.0 -0.8 -1.1 0.5 0.1 -1.1 -1.9 -0.9 -1.5 -0.8 -0.3 -0.4 -0.1 -0.4 -1.7 -0.3 0.1 0.1 0.1
Major Depression (MDD) 2.6 3.1 5.1 -1.7 -2.3 -1.9 -2.1 -0.6 -1.9 -1.6 -1.9 2.1 -0.8 -2.1 -2.2 -1.3 -0.3 -2.1 -2.1 -2.1 -1.8 -1.8 -1.1 -1.9 -1.5 -1.6 -1.6
Reaction Time 1.1 2.2 7.0 0.2 0.8 1.4 1.4 2.1 1.0 1.2 1.9 -1.4 1.1 1.8 2.2 2.1 2.6 1.0 0.9 0.9 1.8 1.4 1.8 1.3 -0.0 -0.2 1.1
Verbal and Numeric Reasoning (VNR) 0.5 1.1 5.6 2.4 0.3 0.8 0.5 -1.9 0.7 0.2 1.2 -0.2 -0.6 -0.6 -2.0 0.5 -0.7 0.3 -0.1 -0.1 0.2 -0.2 -1.8 0.5 0.4 1.2 1.9
Breast Cancer 3.7 8.9 18.3 2.1 2.8 3.0 2.9 4.3 3.0 3.3 2.3 -3.0 -0.7 3.3 3.9 3.2 1.3 3.3 3.3 3.2 3.3 3.0 3.5 3.2 2.7 2.7 2.4
Ovarian Cancer 0.2 0.2 0.9 0.2 0.3 0.4 0.4 -0.1 0.8 0.1 0.1 -0.4 -0.2 0.8 0.9 -0.3 -0.1 0.3 0.4 0.6 0.6 0.4 0.3 0.4 0.3 0.3 0.6
Prostate Cancer 0.6 0.8 2.6 -1.6 -0.5 -1.0 -1.0 0.9 -1.1 -1.2 -1.0 0.8 0.6 -0.0 0.3 -0.5 0.3 -0.7 -0.6 -0.6 -1.0 -0.6 0.1 -1.1 -0.8 -1.3 -1.4
Age at First Birth 0.3 0.4 3.0 -0.5 -0.7 -0.8 -0.6 -1.7 -0.7 -0.2 -1.0 0.5 0.1 -0.6 -1.2 -0.4 -0.8 -0.6 -0.3 -0.6 -0.3 -0.1 -0.5 -0.3 0.1 -0.1 -0.5
Bipolar Disorder (2011) 1.6 1.6 3.6 -0.8 0.0 -1.1 -1.2 -1.0 -0.8 -1.1 -1.3 1.3 -1.6 -1.7 -1.8 -1.0 0.9 -1.5 -1.6 -1.5 -0.9 -1.2 -0.9 -1.3 -1.9 -1.6 -0.9
Body Mass Index (BMI) (2010) 0.2 0.2 1.5 -0.1 0.4 0.1 0.1 -0.2 -0.3 -0.3 -0.6 -0.2 0.4 -0.0 0.0 -1.0 -1.2 0.2 -0.3 -0.1 0.0 0.1 0.4 0.2 0.8 0.6 -0.6
Coronary Artery Disease (CAD) 0.2 0.2 1.7 0.9 0.1 0.4 0.2 -0.7 0.4 0.0 0.0 -0.0 1.3 0.0 -0.3 0.3 0.0 0.2 0.6 0.5 -0.3 -0.1 -0.8 -0.1 -0.1 0.1 0.7
Crohns Disease (2012) 0.5 0.8 3.8 0.2 0.0 -0.1 -0.2 0.6 -0.2 -0.5 0.5 0.5 0.4 -0.2 -0.8 -0.4 1.9 -0.8 0.1 0.2 -0.5 -0.7 -1.9 -0.7 -1.8 -1.6 0.9
Mean Putamen Volume 0.3 0.4 1.1 0.6 0.1 0.6 0.7 0.1 0.8 0.9 0.4 -0.6 0.8 -0.1 -0.5 0.2 1.0 0.2 0.8 0.6 1.1 0.3 0.2 0.6 -0.3 -0.2 0.6
Fasting Glucose 0.4 0.5 2.0 -1.0 -0.4 -0.3 -0.5 0.1 0.5 -1.1 -0.4 0.6 1.1 0.3 0.1 -0.4 0.9 -0.3 -0.3 -0.1 -1.0 0.3 -0.4 -0.7 -0.6 -1.1 -1.4
HbA1C 0.6 0.6 3.5 0.6 1.1 1.0 0.7 -0.3 0.4 0.4 0.7 -0.7 1.9 1.0 0.5 -0.1 0.1 1.0 0.2 0.1 0.4 1.4 0.5 0.7 1.0 0.8 -0.5
HDL Cholesterol 0.2 0.3 0.8 0.9 0.3 0.4 0.4 0.6 0.4 0.9 0.3 -0.3 0.9 0.3 -0.2 0.4 0.2 0.4 0.9 0.8 0.2 0.3 -0.6 0.5 0.5 0.5 0.9
LDL Cholesterol 2.9 4.5 15.7 -1.6 -1.7 -2.1 -2.0 -4.0 -1.6 -3.0 -2.2 2.0 -1.8 -2.6 -2.9 -1.7 -1.2 -2.2 -2.1 -2.5 -1.3 -2.0 -1.4 -1.9 -1.8 -1.5 -1.7
Lupus 0.2 0.2 1.9 -0.1 0.2 0.2 0.1 1.0 0.4 0.0 0.1 -0.1 0.4 0.6 1.4 0.6 0.5 0.3 0.5 0.7 0.3 0.4 0.3 0.3 0.2 0.2 0.2
Neuroticism (2016) 0.5 0.8 2.6 0.4 1.0 0.9 0.8 0.5 0.2 1.6 -0.2 -0.8 -0.0 1.3 1.6 0.1 0.5 0.9 1.0 1.0 0.9 0.9 1.0 0.9 0.7 0.7 0.3
Primary Biliary Cirrhosis 0.1 0.2 1.4 0.3 0.2 0.1 0.1 -0.1 0.3 0.7 -1.2 -0.1 -0.6 0.3 0.2 -1.0 -0.1 0.3 0.4 0.2 -0.5 -0.2 0.0 0.1 0.4 0.4 0.5
Rheumatoid Arthritis 0.6 0.8 3.1 0.4 0.8 0.9 0.9 0.8 1.4 1.1 0.2 -0.9 -0.4 0.7 1.8 1.1 0.9 1.0 1.2 1.1 0.9 0.6 0.6 0.7 0.3 0.5 0.1
Schizophrenia (2014) 0.2 0.5 4.0 0.6 1.1 0.6 0.4 0.9 0.2 0.5 0.7 -0.4 2.0 1.0 0.2 0.6 0.4 0.1 0.1 0.3 0.5 0.3 0.1 0.4 0.3 -0.0 1.3
Triglycerides 0.3 0.6 4.6 0.5 0.4 -0.0 0.1 -2.1 -0.6 -1.0 -0.3 -0.2 0.2 -0.3 -1.2 -0.3 -1.9 0.2 -0.3 -0.1 0.0 0.1 -0.5 0.2 0.8 0.8 -0.1
Type 2 Diabetes (T2D) (2012) 4.9 5.6 8.9 3.0 2.7 3.0 2.9 1.4 1.7 2.4 2.5 -2.8 2.8 2.0 1.4 2.4 0.7 2.7 2.5 2.9 2.5 2.1 1.1 2.4 1.9 2.3 2.8
Ulcerative Colitis 0.2 0.3 1.2 0.5 -0.0 0.2 0.2 -1.1 0.2 0.1 -0.2 0.0 -0.4 -0.2 -0.7 -1.0 1.1 -0.4 -0.1 0.0 0.5 0.4 -0.6 0.0 -0.8 -0.6 0.3
Blood Eosinophil Count 4.0 30.5 43.2 -5.0 -6.6 -5.7 -5.8 -5.2 -4.3 -5.4 -5.2 6.0 -4.8 -5.7 -5.9 -5.9 -0.1 -5.8 -5.2 -5.5 -6.5 -5.2 -5.6 -6.3 -6.0 -5.9 -5.6
Blood Platelet Count 3.4 39.2 127.7 -2.9 -5.0 -7.0 -6.0 -8.8 -6.6 -5.8 -9.8 5.4 -3.1 -5.8 -8.4 -8.3 -11.3 -4.3 -3.6 -4.5 -7.1 -4.8 -6.8 -5.0 1.1 0.3 -5.8
Blood Red Count 0.2 1.8 9.4 -2.2 -0.7 -2.1 -1.7 -0.9 -1.0 -0.8 -1.6 1.1 -1.8 -0.6 -0.2 -1.4 -3.1 -1.1 -0.7 -1.2 -0.5 -1.1 0.9 -1.2 0.3 -0.4 -1.4
Blood White Count 1.0 7.6 15.6 -1.8 -3.5 -2.8 -3.0 0.3 -2.3 -1.9 -1.6 3.5 -1.1 -2.9 -3.4 -2.4 0.6 -3.2 -2.5 -2.3 -3.6 -3.3 -4.0 -3.4 -3.6 -3.1 -1.6
Heel T-Score 5.0 39.4 102.0 5.5 6.2 6.5 6.4 7.5 5.4 4.6 10.1 -6.5 5.9 7.4 5.2 6.8 2.0 6.7 6.2 6.3 6.0 6.4 5.0 6.6 5.9 5.9 6.0
BMI 0.4 2.1 6.6 1.8 1.4 1.2 1.4 -1.7 1.4 0.1 0.2 -1.5 0.9 0.7 -0.5 -0.6 -1.9 1.6 1.9 1.7 0.7 0.8 0.6 1.4 2.6 2.4 1.6
Height 0.7 13.3 107.1 -4.0 -1.4 0.2 -0.6 7.7 1.5 0.7 3.6 0.7 -1.8 1.3 5.2 1.8 10.3 -0.8 -0.1 0.1 0.9 0.4 4.3 -1.1 -5.4 -5.6 -0.9
Waist Hip Ratio (WHR) 1.2 5.3 10.3 -1.9 -2.6 -2.3 -2.5 -0.3 -2.8 -1.1 0.3 2.7 -2.2 -3.0 -2.0 -1.9 -0.3 -2.6 -2.8 -2.7 -2.5 -3.2 -2.5 -2.6 -2.8 -2.3 -1.8
Systolic Blood Pressure 1.6 8.1 16.0 3.5 2.8 3.2 3.4 3.3 2.7 4.0 3.4 -3.3 -0.7 1.9 2.3 1.8 0.4 3.3 3.2 3.0 2.5 2.1 1.5 3.3 2.8 3.3 3.5
Smoking Status 0.2 0.5 3.8 0.4 0.3 1.0 0.8 -0.1 0.7 0.7 1.0 -0.6 -0.2 0.2 0.5 0.6 1.9 0.3 0.6 0.9 0.8 -0.0 0.2 0.3 -0.8 -0.6 1.2
Allergy or Eczema 0.6 1.5 5.3 1.6 1.0 1.6 1.2 1.4 0.9 1.5 0.3 -0.8 2.3 1.1 1.7 1.3 2.0 1.0 0.8 1.3 0.6 1.1 -1.0 0.9 -0.0 0.4 0.8
Cardiovascular Disease 0.4 1.4 5.9 1.5 0.9 1.6 1.4 1.0 0.9 0.7 2.0 -1.3 0.7 0.9 0.7 0.6 1.0 1.1 1.7 1.4 1.1 0.5 -0.2 1.1 0.4 0.7 2.4
Hypothyroidism (self reported) 9.3 21.4 32.0 4.4 5.5 5.2 5.2 4.5 4.4 5.2 3.5 -5.1 2.5 5.1 5.6 3.8 2.4 5.6 5.3 5.7 4.0 4.5 3.7 4.9 4.0 4.5 4.4
Respiratory disease 0.4 0.8 6.0 -0.4 -0.6 -0.0 -0.1 1.6 -0.8 -0.8 0.8 0.3 1.0 0.2 0.9 0.7 2.4 -0.2 -0.6 -0.7 -0.5 -0.1 -0.9 -0.5 -1.6 -1.1 -0.6
Type 2 Diabetes (T2D) (2018) 1.5 2.8 5.8 2.4 2.0 1.9 1.9 1.1 1.1 1.4 1.9 -1.8 1.1 1.2 0.6 1.2 -1.3 1.9 1.8 2.0 1.5 1.3 -0.1 1.8 2.4 2.2 1.9
Lung FEV1/FVC ratio 2.8 14.1 29.8 -3.1 -3.4 -4.0 -4.0 -5.0 -3.9 -3.1 -2.1 4.0 -1.5 -4.6 -3.9 -5.5 -3.1 -4.3 -3.7 -3.7 -4.0 -4.8 -3.3 -3.9 -2.8 -2.9 -2.9
Lung FVC 1.0 5.1 9.9 1.4 2.4 2.2 2.4 -0.6 2.7 1.4 1.3 -2.7 0.6 2.7 3.1 1.9 -0.1 2.8 2.1 2.1 2.6 3.1 3.0 2.8 2.9 2.6 1.1
Neuroticism 2.2 5.3 14.3 -1.9 -2.2 -2.4 -2.3 -2.3 -2.8 -1.0 -2.1 2.3 -1.8 -2.7 -1.7 -3.8 -1.8 -2.2 -2.2 -2.0 -2.6 -2.5 -2.9 -2.3 -1.6 -1.7 -2.8
Chronotype (morning person) 0.3 0.8 2.8 -1.7 -1.0 -0.9 -0.8 1.3 -0.7 -0.7 -1.5 0.7 -0.4 -0.2 0.7 -0.1 0.9 -0.8 -0.2 -0.4 -0.5 -0.9 0.6 -0.9 -1.1 -1.5 -0.8
Hair Pigment 0.3 7.7 15.2 -2.8 -3.0 -2.7 -3.0 -1.4 -3.0 -2.8 -0.7 3.2 -2.0 -3.3 -2.5 -1.6 0.8 -3.3 -3.2 -3.0 -2.8 -3.0 -2.1 -3.4 -3.9 -3.4 -2.7
Tanning 0.3 3.3 11.2 0.6 1.5 2.0 1.9 1.6 1.8 0.9 0.3 -1.9 0.8 2.7 1.6 2.3 3.3 1.7 1.4 1.1 2.5 2.7 3.0 1.6 0.2 0.5 0.9
Hand grip strength (left) 1.1 2.8 6.3 1.7 1.8 1.7 1.7 1.0 1.7 1.9 0.1 -1.9 0.0 1.7 1.1 1.3 -0.8 2.0 1.5 1.6 1.8 1.7 1.7 2.1 2.5 2.3 1.9
Number of treatments/medications taken 0.3 0.5 2.9 0.5 0.4 1.0 0.5 1.6 -0.4 0.5 0.8 -0.3 0.6 0.6 0.8 0.3 1.7 0.5 0.5 0.8 0.0 0.3 0.1 0.3 -0.4 -0.1 1.0
Average weekly spirits intake 0.2 0.2 1.0 0.2 -0.9 -0.4 -0.3 0.1 -0.2 -0.4 0.4 0.4 0.0 -0.5 -1.0 0.7 -0.5 -0.6 -0.4 -0.2 -0.3 -0.3 -0.9 -0.5 -0.3 -0.3 -0.5
Sensitivity / hurt feelings 3.2 5.4 10.4 -1.6 -2.2 -2.7 -2.4 -2.1 -2.9 -1.9 -2.0 2.3 -1.6 -2.7 -2.6 -3.2 -2.9 -2.1 -2.4 -2.4 -2.4 -2.1 -2.7 -2.2 -1.0 -1.1 -2.8
Frequency of depressed mood in last 2 weeks 1.0 1.4 3.5 -0.8 -1.1 -1.2 -1.2 -1.0 -1.4 -0.7 -0.9 1.2 -1.2 -1.7 -1.0 -1.2 -1.5 -1.3 -1.9 -1.6 -1.0 -1.4 -1.4 -1.1 -0.5 -0.7 -0.9
Hearing difficulty/problems: Yes 2.0 3.0 11.9 -1.4 -2.1 -1.9 -1.6 -2.1 -1.5 -1.2 -1.2 1.5 -2.7 -1.4 -1.7 -3.5 -2.2 -1.4 -1.1 -1.2 -1.6 -1.5 -1.8 -1.5 -0.4 -0.7 -1.6
Relative age of first facial hair 0.2 0.5 6.8 -0.2 -0.5 -0.2 -0.5 0.1 1.2 -0.3 -2.6 0.6 -1.1 -0.0 0.3 -0.5 0.3 -0.6 -0.0 0.3 0.1 0.2 -0.5 -0.2 -0.2 -0.6 -0.3
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 0.6 0.5 -0.2 0.2 0.0 -0.2 -0.1 -0.0 0.7 0.1 0.4 0.3 -0.2 -0.3 -0.2 -0.2 -0.7 -0.1 -0.3 0.1 -0.8 -0.2 -0.1 0.1 -0.3
Ever used hormone-replacement therapy (HRT) 0.3 0.4 2.5 0.7 0.3 0.1 0.2 -0.1 0.6 0.5 0.2 -0.3 -0.6 0.5 0.4 -0.5 -1.6 0.5 0.0 0.1 0.0 0.5 -0.1 0.5 1.4 1.1 0.1
Ever had hysterectomy (womb removed) 2.0 2.3 5.7 1.4 1.2 1.4 1.5 2.1 1.3 1.1 2.4 -1.4 -0.0 1.6 2.1 1.8 1.0 1.6 1.7 1.9 1.1 1.1 1.1 1.5 1.0 1.0 1.9
Systolic blood pressure, automated reading 1.3 3.7 12.1 2.4 1.7 2.2 2.2 2.4 1.2 2.7 3.5 -2.1 -0.4 1.2 1.6 0.7 -0.1 2.1 1.9 2.2 1.6 1.2 0.9 2.1 1.7 2.4 2.1
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 2.2 -0.0 -0.2 -0.2 -0.3 1.5 -0.1 -0.3 -0.1 0.5 -0.4 -0.2 0.2 -0.1 -0.2 -0.4 -0.7 -0.5 -0.6 -0.5 -1.3 -0.4 -0.4 -0.4 -0.7
Angina 0.5 0.7 2.0 -1.1 -0.4 -0.5 -0.8 -0.2 -0.5 -0.9 0.2 0.9 0.8 -1.0 -0.6 0.4 1.4 -0.9 -0.9 -1.2 -0.6 -0.8 -0.0 -0.8 -1.4 -1.3 -0.1
Medication for hormone replacement therapy 0.5 0.6 3.2 1.3 0.7 0.5 0.3 0.3 0.1 0.6 -0.2 -0.2 -1.0 0.2 -0.0 -0.1 -1.8 0.6 0.7 1.0 -0.0 -0.1 -1.0 0.4 1.3 1.4 0.8
Vitamin and mineral supplements 0.3 0.5 1.4 -1.2 -0.5 -0.9 -0.7 0.0 -0.9 -1.1 -1.1 0.5 0.2 -0.4 0.1 -0.4 0.5 -0.5 -0.2 -0.4 -0.6 -0.4 0.3 -0.8 -0.9 -0.8 -1.0
Supplements: Zinc 0.8 0.9 3.5 0.3 0.2 0.4 0.7 1.4 1.3 1.9 -0.6 -0.8 -1.5 0.4 1.3 0.5 -0.4 0.7 1.6 1.6 0.7 0.1 0.3 0.5 0.8 0.4 0.7
Medication: Co-codamol 0.2 0.2 0.6 -0.7 -0.3 -0.4 -0.5 0.4 -0.0 -0.3 -0.1 0.5 -0.0 -0.0 0.4 -0.1 0.3 -0.5 -0.5 -0.2 -0.5 -0.3 0.1 -0.5 -0.7 -0.7 -0.8
Medication: Metformin 0.3 0.4 2.4 0.6 0.4 0.3 0.2 -1.0 0.3 -0.5 0.9 -0.1 1.6 -0.1 -1.1 0.1 -0.3 0.2 0.9 0.9 -0.1 0.1 -0.9 0.1 0.3 0.1 0.5
Diabetes (father) 5.8 7.2 10.8 2.7 3.0 3.2 3.1 1.1 2.2 2.4 1.8 -3.0 2.7 2.8 2.5 2.5 1.2 3.0 3.0 3.0 3.3 2.9 2.2 3.1 2.3 2.6 3.2
Diabetes (mother) 2.9 3.7 6.6 -2.2 -1.7 -2.1 -2.1 -1.5 -2.6 -1.3 -1.9 2.1 -0.2 -2.4 -1.6 -1.8 -0.1 -2.1 -2.2 -2.3 -2.0 -2.3 -0.8 -2.1 -2.0 -1.9 -2.0
Severe depression (siblings) 0.2 0.2 1.7 0.1 -0.6 -0.2 -0.3 -0.4 -0.0 0.3 -0.3 0.4 -0.6 -0.3 -1.3 -0.1 0.2 -0.3 -0.4 -0.3 -0.4 0.0 -0.6 -0.2 -0.2 -0.1 0.2
Pack years adult smoking proportion 1.3 2.0 4.5 1.3 1.6 1.7 1.5 0.9 1.3 1.0 1.1 -1.4 1.1 1.6 1.5 2.1 1.3 1.5 1.9 1.9 1.3 1.4 0.9 1.4 0.8 0.8 1.5
Impedance of leg (right) 2.7 13.2 22.2 -2.4 -4.0 -3.7 -4.1 -2.6 -3.5 -2.5 -2.8 4.3 -3.2 -4.5 -4.1 -3.2 -1.6 -4.6 -4.3 -4.2 -3.2 -4.0 -4.7 -3.8 -3.7 -3.6 -2.2
Leg fat-free mass (left) 0.9 4.7 13.4 0.7 1.7 2.2 2.2 3.2 2.6 1.7 2.1 -2.2 0.6 2.2 2.8 2.0 3.7 2.3 2.6 2.6 1.9 1.8 3.1 1.6 0.3 0.5 1.3
Trunk fat percentage 0.1 0.5 1.7 1.2 0.2 0.6 0.7 -1.3 0.6 0.0 0.8 -0.6 0.0 -0.3 -1.2 -0.5 -0.2 0.6 1.1 1.2 -0.1 -0.1 -0.5 0.3 0.3 0.6 1.3
Hand grip strength (right) 0.9 2.6 4.5 2.0 1.6 1.9 1.9 1.3 1.9 1.7 0.3 -1.9 0.1 1.6 0.5 2.0 0.5 1.8 1.1 1.2 2.1 1.7 1.5 1.9 1.6 1.6 2.1
Townsend deprivation index at recruitment 2.0 2.8 5.6 -2.1 -1.8 -1.8 -1.9 -0.3 -1.4 -1.4 -1.4 1.9 -0.7 -1.6 -0.7 -1.6 0.5 -2.0 -1.5 -1.5 -2.1 -1.6 -1.4 -2.2 -2.1 -2.4 -2.2
Current tobacco smoking 0.4 0.7 3.4 0.8 0.7 1.0 0.8 0.8 0.7 0.9 0.7 -0.6 -0.1 0.1 1.5 0.8 0.5 0.4 1.2 1.8 0.5 -0.5 -0.4 0.4 -0.1 0.1 1.6
Average weekly fortified wine intake 2.1 2.5 6.7 2.1 1.7 1.6 1.6 0.9 0.9 2.0 0.8 -1.7 0.4 1.4 0.8 1.6 -1.2 1.8 1.5 1.5 1.2 1.2 0.7 1.9 2.6 2.4 2.0
Maternal smoking around birth 2.9 4.3 6.7 1.6 2.1 2.4 2.6 1.5 1.6 2.2 2.6 -2.6 1.8 2.1 2.3 0.9 1.7 2.5 2.4 2.4 2.1 2.3 2.0 2.2 1.4 1.6 1.6
Fed-up feelings 0.8 1.4 6.2 -1.0 -0.7 -1.3 -1.0 -0.8 -1.7 -0.3 -1.4 0.9 0.3 -1.6 -0.4 -1.8 -2.5 -1.0 -1.0 -1.0 -0.9 -1.5 -1.1 -1.1 -0.0 -0.2 -1.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.4 -0.4 -0.6 -0.3 -0.4 -1.0 -0.3 0.2 0.1 0.5 -1.2 -1.1 -0.3 -0.6 0.2 -0.5 -0.8 -0.6 -0.6 -0.7 -0.7 -0.6 -0.8 -0.7 -0.2
Relative age voice broke 0.3 0.4 2.3 0.7 -0.6 -0.0 -0.2 -0.3 -0.1 0.2 -1.0 0.3 -1.1 -0.6 -0.7 -0.1 -1.5 -0.3 0.1 0.5 0.3 -0.4 -1.0 0.2 0.7 0.5 0.6
Taking other prescription medications 0.2 0.3 1.1 -0.3 -0.2 -0.1 -0.3 0.2 -0.6 -0.2 0.2 0.5 0.7 -0.4 -0.1 -0.6 1.1 -0.3 -0.6 -0.5 -1.0 -0.7 -0.7 -0.5 -0.8 -0.7 0.3
Age when periods started (menarche) 0.8 2.0 6.4 0.8 0.5 1.5 1.4 0.7 2.5 1.2 0.8 -1.4 1.4 2.3 0.6 1.4 2.4 1.2 1.2 1.3 1.5 2.0 1.4 1.3 0.3 0.0 1.3
Bilateral oophorectomy (both ovaries removed) 2.7 3.2 8.0 2.2 1.4 1.7 2.0 2.3 1.7 1.5 1.8 -2.0 0.9 1.5 1.6 1.9 -0.0 1.9 1.8 1.6 1.7 1.4 0.9 1.9 2.1 1.9 2.8
Heel bone mineral density (BMD) T-score, automated (left) 2.6 6.0 13.8 2.9 2.2 2.7 2.8 2.3 1.6 1.8 3.7 -2.7 1.0 2.7 1.2 2.9 0.3 2.7 2.6 2.7 2.6 2.6 1.3 2.7 2.3 2.8 2.9
Tinnitus: Yes, but not now, but have in the past 0.8 0.9 2.9 -0.3 -0.8 -0.9 -0.7 -1.4 -0.9 -0.8 -1.3 0.7 0.2 -0.7 -1.7 -1.3 -1.3 -0.7 -0.8 -0.7 -1.2 -0.4 -1.2 -0.7 0.0 -0.3 -1.0
Qualifications: CSEs or equivalent 0.7 0.9 5.6 -0.2 -0.5 -0.7 -0.7 -1.1 -0.3 -0.3 -2.4 0.9 -2.4 -0.9 -0.2 -1.3 -0.4 -0.9 -0.5 -0.2 -0.7 -0.9 -1.0 -0.8 -0.9 -0.5 -0.6
Serious illness, injury or assault to yourself 0.4 0.5 2.7 0.3 -0.4 -0.3 -0.5 -0.3 -1.0 0.0 0.4 0.6 1.1 -0.6 -0.3 -1.0 -1.0 -0.5 -0.7 -0.4 -0.9 -0.6 -1.6 -0.5 0.0 0.1 -1.0
High blood pressure 0.9 2.5 5.4 1.6 1.6 2.2 2.0 1.3 1.1 1.4 2.3 -1.8 0.6 1.1 1.7 1.1 1.3 1.8 2.1 1.9 1.8 1.1 0.7 1.6 0.7 1.1 2.3
Hayfever, allergic rhinitis or eczema 0.6 1.2 3.5 1.4 0.9 1.4 1.1 1.7 1.0 1.2 0.1 -0.7 1.5 1.1 1.6 1.6 1.9 0.8 0.5 0.9 0.7 0.8 -0.9 0.8 -0.1 0.3 1.1
Multivitamins +/- minerals 1.3 1.6 3.7 1.8 1.4 1.5 1.3 0.7 1.2 1.9 0.6 -1.3 -0.0 0.9 0.5 0.9 -0.6 1.3 1.2 1.3 1.4 1.0 0.7 1.5 1.7 1.7 1.9
Stomach or abdominal pain in last month 0.4 0.5 1.9 1.4 0.4 0.4 0.5 0.2 -0.0 1.1 0.6 -0.4 -0.2 -0.8 -0.4 -0.2 -1.4 0.3 0.4 0.5 0.1 -0.3 -1.2 0.3 0.8 0.9 1.0
Supplements: Glucosamine 1.9 2.5 5.8 1.8 1.4 1.5 1.7 0.6 2.4 1.9 1.4 -1.8 0.2 1.5 0.5 1.6 0.3 2.0 1.9 1.6 1.0 1.9 1.2 1.8 2.0 1.9 1.4
Diverticular disease/diverticulitis (self-reported) 1.4 1.6 3.1 1.3 1.4 1.8 1.5 1.2 0.6 1.3 0.4 -1.3 1.1 1.6 1.2 1.2 1.7 1.4 1.1 1.3 1.4 1.6 0.9 1.3 0.7 0.9 1.3
Medication: Atenolol 0.6 0.8 2.0 0.5 1.1 1.2 1.0 0.3 1.4 0.6 0.5 -1.0 0.5 0.7 0.3 0.8 1.4 0.9 1.1 0.8 0.9 0.9 0.8 0.9 0.2 0.2 1.4
Medication: Levothyroxine sodium 8.6 14.6 22.7 3.9 4.2 4.4 4.4 3.3 3.8 3.9 3.8 -4.3 2.4 4.0 4.6 3.2 1.8 4.4 4.6 4.8 3.6 3.5 2.6 4.0 3.1 3.6 3.9
Sitting height 0.8 5.8 16.4 1.9 1.7 2.8 2.5 4.0 2.6 2.0 3.5 -2.3 0.0 1.8 1.9 2.1 4.0 2.3 2.6 2.6 2.3 2.0 2.2 2.1 0.2 0.7 2.8
Chronic bronchitis/emphysema (father) 0.8 1.0 2.9 0.7 1.1 0.9 1.1 -0.4 0.4 0.8 0.9 -1.2 1.4 1.2 -0.0 0.7 -0.0 1.2 1.2 1.1 0.8 1.7 1.0 1.0 1.2 1.1 0.3
High blood pressure (mother) 0.9 1.3 2.8 1.5 1.1 1.3 1.4 0.5 0.6 1.4 1.7 -1.3 0.7 0.9 0.6 1.1 0.2 1.3 1.3 1.4 0.8 0.7 0.0 1.3 0.9 1.3 1.6
Body mass index (BMI) 0.2 1.0 3.1 1.1 0.8 0.6 1.0 -1.8 0.8 -0.1 0.3 -1.1 0.7 0.3 -0.6 -0.6 -1.3 1.2 1.4 1.4 0.0 0.3 0.5 0.7 1.6 1.6 0.8
Impedance of leg (left) 2.2 10.6 17.9 -2.0 -3.6 -3.3 -3.6 -3.0 -3.2 -2.3 -2.6 3.9 -3.2 -3.9 -4.0 -2.5 -1.3 -4.1 -3.8 -3.6 -2.9 -3.5 -4.2 -3.4 -3.4 -3.2 -1.9
Leg predicted mass (left) 0.9 4.7 14.1 0.7 1.6 2.2 2.2 3.2 2.6 1.7 2.1 -2.2 0.6 2.2 2.8 2.0 3.8 2.3 2.6 2.6 1.8 1.8 3.1 1.6 0.2 0.5 1.3
Trunk fat mass 0.1 0.5 2.0 0.9 0.3 0.7 0.9 -0.4 0.9 0.2 0.8 -0.8 -0.0 -0.0 -0.6 -0.2 0.7 0.8 1.4 1.4 0.2 0.0 0.2 0.4 0.1 0.4 1.3
Waist circumference 0.2 0.7 2.1 -0.6 -1.0 -0.7 -0.6 -0.8 -0.7 -0.8 0.2 0.7 -0.6 -1.2 -1.0 -1.4 0.4 -0.6 -0.3 -0.3 -1.3 -1.5 -0.6 -1.0 -1.1 -0.8 -0.4
Number of incorrect matches in round 2.7 4.4 7.4 -2.7 -2.0 -2.2 -2.2 -1.6 -2.7 -1.6 -1.6 2.1 -1.6 -2.6 -1.1 -2.5 0.2 -2.1 -2.2 -2.3 -2.2 -2.4 -1.2 -2.4 -2.4 -2.5 -2.4
Past tobacco smoking 0.3 0.6 2.9 1.0 0.6 0.5 0.5 1.7 0.5 0.4 -0.3 -0.5 1.2 0.5 0.9 1.0 -0.6 0.5 0.9 1.1 -0.0 0.0 -0.3 0.4 0.8 0.9 0.9
Alcohol usually taken with meals 0.2 0.4 3.0 0.3 0.1 -0.3 -0.2 -0.7 0.1 -0.3 0.1 0.0 -0.3 0.0 -1.1 -0.8 -1.7 -0.0 -0.3 -0.7 0.0 0.3 0.0 0.2 1.2 0.8 0.1
Nervous feelings 2.3 4.3 7.1 -2.2 -2.3 -2.2 -2.3 -0.6 -2.2 -1.0 -1.5 2.4 -2.5 -2.4 -0.6 -2.4 0.1 -2.4 -2.0 -1.9 -2.0 -2.6 -2.0 -2.3 -2.7 -2.5 -2.1
Frequency of tenseness / restlessness in last 2 weeks 0.7 1.0 3.0 -1.5 -1.0 -1.1 -1.1 0.7 -1.7 -0.3 -0.2 1.0 0.4 -1.4 0.2 -1.2 -0.4 -0.9 -1.1 -1.2 -1.0 -1.3 -0.6 -1.1 -0.9 -1.0 -1.3
Hearing difficulty/problems with background noise 2.2 3.6 9.1 -2.0 -2.2 -2.1 -1.8 -2.5 -1.9 -1.3 -1.6 1.7 -3.0 -2.2 -0.9 -3.0 -1.5 -1.8 -1.5 -1.4 -1.3 -2.0 -1.3 -1.8 -1.3 -1.5 -2.0
Hair/balding pattern: Pattern 2 1.4 1.7 5.8 1.9 1.3 1.5 1.9 0.8 0.2 1.5 0.9 -1.8 -0.7 0.8 0.9 0.8 -0.5 1.6 0.7 0.9 1.4 0.6 0.7 1.6 1.6 1.9 2.4
Had menopause 0.5 0.6 3.3 0.6 0.6 0.8 0.7 -0.6 0.3 0.6 1.8 -0.7 -0.9 1.1 1.1 -0.9 -0.3 0.8 0.3 0.4 0.6 0.8 0.6 0.6 0.8 0.8 0.5
Had other major operations 0.8 0.9 2.1 -1.4 -1.4 -0.9 -1.1 -0.7 -1.2 -0.8 -0.1 1.1 0.0 -0.5 -0.2 -1.0 1.0 -1.1 -0.8 -0.8 -1.3 -1.0 -0.3 -1.1 -1.3 -1.5 -0.5
Forced vital capacity (FVC) 0.8 3.2 6.4 0.8 1.5 1.6 1.9 1.8 2.3 1.9 0.6 -2.1 -0.5 2.0 2.2 2.0 1.1 2.0 1.8 1.5 2.4 2.2 2.5 2.0 1.5 1.3 1.4
Heel bone mineral density (BMD) T-score, automated (right) 2.5 5.6 15.3 2.2 1.9 2.5 2.5 2.2 1.8 1.7 3.9 -2.5 2.1 2.6 1.1 3.0 0.9 2.6 2.5 2.5 2.4 2.7 1.7 2.6 2.1 2.3 2.8
Ever unenthusiastic/disinterested for a whole week 1.5 1.8 5.4 -1.1 -1.6 -1.4 -1.2 -0.2 -1.2 -0.3 -2.3 1.2 -1.6 -1.5 -0.7 -1.9 -1.4 -1.4 -1.4 -1.3 -1.1 -1.9 -1.5 -1.3 -0.7 -1.0 -0.9
Qualifications: None of the above 0.5 1.1 5.8 -2.4 -0.8 -1.3 -1.1 0.4 -0.4 -1.0 0.8 0.7 -1.2 -0.1 1.3 -0.8 0.1 -0.7 -0.2 -0.3 -0.6 -0.3 1.2 -1.0 -0.6 -1.6 -2.0
Financial difficulties in last 2 years 0.4 0.5 1.5 -0.9 -0.4 -0.7 -0.7 -0.1 -0.4 -0.5 0.0 0.7 -0.5 -0.6 -0.8 -0.7 0.4 -0.8 -1.2 -1.2 -0.8 -0.6 -0.1 -0.8 -1.0 -1.0 -0.4
Mouth/teeth dental problems 0.8 1.2 4.8 -0.3 -0.6 -0.9 -0.9 -1.8 -0.8 -0.6 -1.8 0.9 0.1 -1.0 -2.2 -1.4 -1.4 -0.7 -0.6 -0.5 -1.5 -1.2 -1.7 -1.0 -0.2 -0.4 -0.2
Heart attack 0.1 0.2 1.0 -0.4 0.3 0.1 0.1 0.1 -0.6 0.0 0.4 -0.2 -0.0 -0.0 0.2 0.0 0.2 -0.0 -0.6 -0.5 0.8 0.4 1.0 0.2 -0.1 -0.0 -0.7
Allergy 0.6 1.3 8.3 -1.1 -0.5 -1.3 -1.0 -2.0 -0.8 -0.7 -0.9 0.7 -1.2 -1.0 -1.5 -2.1 -2.9 -0.7 -0.5 -0.7 -0.6 -0.7 0.6 -0.5 0.8 0.3 -0.8
Pain all over the body in last month 0.2 0.2 1.4 0.4 -0.1 0.2 -0.0 0.7 -0.2 -0.5 -0.5 0.2 0.4 0.1 0.0 1.2 0.5 0.0 0.2 0.4 -0.4 -0.0 -1.0 -0.3 -0.5 -0.3 -0.2
Diabetes (self-reported) 0.3 0.5 2.7 0.9 0.7 0.9 0.7 0.6 0.4 0.1 1.6 -0.6 1.3 0.6 -0.1 0.5 0.5 0.8 1.0 1.0 0.2 0.7 -0.5 0.5 0.3 0.5 0.4
Hayfever/allergic rhinitis (self-reported) 0.9 1.2 5.4 1.2 0.5 1.3 1.0 0.8 1.3 1.0 2.3 -0.6 1.7 0.8 0.7 1.5 2.3 0.8 0.7 0.8 -0.3 0.5 -0.9 0.5 -0.4 -0.1 1.1
Medication: Ramipril 0.3 0.3 1.4 -1.2 -0.2 -0.1 -0.2 0.7 0.3 -0.2 -0.2 0.0 -0.6 0.5 0.9 0.7 0.9 -0.1 0.6 0.5 0.4 0.1 1.1 -0.2 -0.6 -1.0 -0.3
Medication: Simvastatin 0.4 0.6 4.3 0.4 0.5 0.9 0.7 0.5 0.3 -0.0 1.2 -0.6 2.1 0.8 0.6 -0.4 0.9 0.8 0.8 0.7 0.2 1.0 0.2 0.6 0.5 0.5 0.0
Fluid intelligence score 0.4 0.8 3.7 1.9 0.3 0.9 0.7 -1.2 1.0 0.1 0.6 -0.3 -0.2 -0.5 -1.9 1.0 0.3 0.2 0.0 -0.1 0.7 0.1 -1.1 0.6 0.1 0.7 1.9
Illnesses of siblings 0.2 0.3 1.9 0.5 0.7 0.3 0.4 0.3 1.4 0.1 0.0 -0.3 0.3 0.7 -0.1 0.8 0.9 0.5 0.7 0.7 0.3 1.0 0.1 0.3 0.1 0.3 -0.5
Neuroticism score 2.9 6.1 12.7 -2.3 -2.5 -2.8 -2.5 -1.8 -3.2 -1.4 -2.5 2.5 -1.9 -3.1 -2.0 -3.6 -1.9 -2.5 -2.4 -2.3 -2.4 -2.7 -2.6 -2.6 -2.0 -2.0 -2.9
Weight 0.2 0.8 4.5 0.1 0.3 0.7 0.9 0.7 1.3 0.3 1.1 -0.8 -0.4 0.5 0.6 0.1 2.1 0.9 1.4 1.4 0.4 0.3 1.4 0.3 -0.3 -0.3 0.7
Impedance of arm (right) 0.1 0.7 3.7 0.8 -0.7 0.0 -0.3 1.0 -0.6 0.5 0.1 0.7 -1.6 -0.9 -0.6 -0.1 0.6 -0.8 -0.5 -0.2 -0.2 -0.8 -1.9 -0.4 -1.3 -0.6 1.1
Arm fat percentage (right) 0.3 1.4 4.1 2.0 1.0 1.1 1.3 -1.2 0.8 0.3 0.8 -1.2 0.5 0.2 -0.8 -0.3 -1.1 1.4 1.7 1.7 0.3 0.4 -0.2 1.0 1.5 1.8 1.8
Trunk fat-free mass 0.4 2.6 15.4 -0.7 0.5 1.0 1.0 3.1 1.7 0.8 1.3 -1.1 -0.3 1.4 2.5 1.4 3.9 1.2 1.3 1.2 1.2 1.0 2.9 0.6 -0.9 -0.9 -0.0
Hip circumference 0.2 0.9 3.0 0.8 0.8 1.1 1.2 0.3 1.7 0.3 0.6 -1.1 0.3 0.9 0.6 0.6 1.3 1.2 1.5 1.5 0.6 0.6 1.1 0.7 0.4 0.5 1.2
Time employed in main current job 1.0 1.1 2.4 -0.7 -1.2 -1.2 -1.0 -0.5 -1.5 -1.0 -0.4 1.0 0.2 -1.4 -1.5 -1.2 -1.1 -0.9 -0.9 -0.9 -1.6 -1.4 -1.5 -1.1 -0.6 -0.6 -0.8
Alcohol intake versus 10 years previously 0.9 1.3 3.7 0.7 1.6 1.0 1.2 0.5 0.9 1.2 0.2 -1.3 1.9 1.2 1.3 0.8 0.1 1.3 1.4 1.4 0.8 1.3 1.1 1.1 1.4 1.1 0.4
Father’s age at death 1.2 1.7 3.6 1.3 1.4 1.4 1.3 1.3 1.1 1.6 1.2 -1.2 -0.0 1.1 1.8 1.9 0.2 1.1 0.4 0.5 1.9 1.0 1.4 1.5 1.2 1.4 1.4
Worrier / anxious feelings 0.3 0.5 3.5 -0.3 -0.9 -0.8 -0.3 -0.6 -0.4 0.5 -0.2 0.3 -0.9 -0.9 -0.2 -1.4 -1.9 -0.4 -0.1 -0.3 -0.3 -0.8 -1.3 -0.3 0.3 0.2 -0.5
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 2.4 -1.2 -1.5 -1.3 -1.1 0.0 -1.4 0.1 -1.3 1.0 -0.6 -1.5 -0.1 -1.3 -0.7 -1.1 -0.8 -1.1 -1.2 -1.3 -0.7 -1.1 -0.7 -1.0 -1.0
Falls in the last year 1.1 1.5 4.0 1.1 0.7 1.3 1.3 1.5 0.8 1.6 2.0 -1.2 0.1 0.1 1.4 1.5 1.5 1.1 1.5 1.6 1.3 0.6 1.0 1.1 0.1 0.6 1.4
Hair/balding pattern: Pattern 3 0.6 0.9 3.8 -1.3 -0.5 -1.1 -0.8 -1.7 -0.5 -0.8 -1.4 0.5 -0.2 -0.4 -0.5 -1.0 -1.1 -0.6 -1.1 -1.5 -0.0 0.3 0.9 -0.4 0.2 -0.1 -2.0
Number of live births 0.4 0.6 3.1 0.2 0.8 0.7 0.7 -0.8 1.2 0.4 -0.3 -0.8 -0.9 0.9 0.6 0.3 1.0 0.8 0.4 0.5 0.7 0.9 1.8 0.7 0.2 0.3 0.4
Forced expiratory volume in 1-second (FEV1) 0.0 0.1 0.6 -0.2 0.3 -0.1 0.2 -0.1 0.7 0.4 -0.4 -0.4 -0.5 0.2 0.3 0.1 -0.4 0.3 0.4 0.1 0.4 0.3 0.8 0.4 0.6 0.3 0.2
Pulse rate 2.7 4.5 7.7 -1.7 -2.3 -2.5 -2.3 -1.5 -2.6 -1.6 -1.3 2.2 -0.0 -2.7 -2.7 -2.1 -2.7 -2.3 -2.0 -2.4 -2.3 -2.4 -2.8 -2.3 -1.1 -1.3 -1.9
Happiness 0.1 0.2 1.5 -0.3 -0.1 -0.1 -0.0 -0.2 -0.0 0.2 0.1 -0.2 1.2 0.8 0.4 0.4 -0.6 0.0 0.2 0.1 0.0 -0.1 0.3 0.1 0.7 0.0 0.2
Noisy workplace 0.2 0.3 1.0 -0.2 0.5 0.2 0.3 -0.0 0.0 0.3 -0.3 -0.5 0.7 0.2 1.0 0.0 -0.7 0.7 0.7 0.7 -0.1 -0.2 0.8 0.4 0.8 0.5 0.4
Qualifications: A levels/AS levels or equivalent 0.5 1.2 3.2 1.8 1.3 1.3 1.2 0.4 1.7 0.8 0.7 -1.2 0.7 1.0 -0.0 1.0 -0.3 1.1 0.9 0.9 1.0 1.1 0.2 1.3 1.4 1.5 1.5
Serious illness, injury or assault of a close relative in last 2 years 2.4 2.8 5.4 2.3 1.9 2.2 2.1 0.1 1.2 1.6 2.3 -2.0 2.0 1.4 0.3 1.1 0.5 2.0 1.4 1.4 1.4 1.4 0.3 2.0 1.6 1.9 2.3
Mouth/teeth dental problems: Dentures 1.2 2.0 12.3 -1.4 0.5 0.5 0.6 1.6 1.3 0.5 2.0 -0.9 -0.8 1.5 3.5 0.6 2.1 0.7 0.7 0.7 1.4 1.2 3.2 0.8 -0.1 -0.4 -0.7
Asthma 1.0 2.0 8.0 0.8 0.9 1.5 1.3 2.5 0.6 0.7 1.2 -1.2 1.5 1.8 2.0 2.1 2.8 1.4 1.2 0.9 1.0 1.5 1.0 1.1 -0.0 0.4 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 0.9 -0.3 -0.4 -0.4 -0.3 0.2 -0.3 -0.0 -0.9 0.3 0.1 -0.1 -0.9 0.5 0.8 -0.3 -0.2 -0.4 -0.6 -0.2 -0.1 -0.5 -0.7 -0.5 -0.5
Medication: Cholesterol lowering 0.5 0.7 2.4 -0.4 -0.5 -0.6 -0.7 -0.5 -1.5 -1.5 0.1 0.7 0.8 -1.0 -0.9 -1.0 -0.4 -0.7 -0.8 -0.9 -0.6 -0.5 -1.5 -0.7 -0.6 -0.6 -0.6
Depression (self-reported) 1.1 1.3 4.5 -1.0 -1.3 -1.2 -1.1 -1.5 -2.1 -0.5 -1.4 1.0 -1.0 -1.6 -1.2 -1.6 -1.5 -0.9 -1.1 -1.2 -1.0 -1.3 -0.4 -0.8 -0.2 -0.3 -0.6
Medication: Lansoprazole 0.5 0.6 4.6 -0.3 -0.7 -0.6 -0.8 -2.1 -0.3 -1.0 -0.3 0.9 -0.2 -0.7 -0.8 -0.2 -0.0 -0.8 -0.6 -0.5 -0.8 -0.6 -0.9 -0.9 -0.8 -0.6 -0.7
Prospective memory result 1.5 1.9 4.0 -1.1 -1.3 -1.4 -1.3 -0.7 -1.9 -1.4 -0.9 1.3 -0.3 -1.6 -1.1 -1.4 -1.5 -1.4 -1.5 -1.2 -1.5 -1.7 -2.0 -1.6 -1.0 -1.0 -1.4
Lung cancer (father) 1.2 1.4 4.0 -1.5 -1.0 -1.0 -1.2 -1.5 -0.9 -2.0 -1.0 1.2 -0.5 -0.4 -0.6 -1.6 0.7 -1.3 -1.2 -1.1 -0.8 -0.4 -0.2 -1.2 -1.6 -1.7 -1.6
Illnesses of mother 0.3 0.3 2.1 -0.8 0.3 -0.2 -0.1 -1.0 0.5 -0.8 -1.5 -0.1 -0.6 0.4 0.2 -0.1 -0.2 0.1 -0.1 -0.2 0.3 0.5 0.8 -0.1 0.1 -0.3 -1.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 1.4 -0.5 0.1 -0.2 0.1 -0.4 0.5 0.5 -1.2 -0.3 -0.9 0.0 0.1 0.2 0.4 0.2 0.4 -0.0 0.3 0.2 1.2 0.2 0.1 -0.2 0.1
Pulse wave Arterial Stiffness index 0.3 0.3 1.6 0.7 0.3 0.4 0.4 0.8 -0.5 0.9 -0.2 -0.4 1.3 0.3 0.4 0.3 -0.2 0.5 0.6 0.7 -0.0 0.2 -0.2 0.3 0.6 0.6 0.9
Impedance of arm (left) 0.1 0.6 4.0 1.1 -0.4 0.2 -0.0 0.8 -0.1 0.8 -0.2 0.4 -1.2 -0.8 -0.8 -0.0 0.4 -0.6 -0.4 -0.2 0.1 -0.5 -2.0 -0.1 -0.9 -0.3 1.3
Arm fat mass (right) 0.2 0.8 2.7 1.3 0.7 1.0 1.2 -0.4 1.0 0.3 0.8 -1.1 0.3 0.4 -0.1 0.0 0.1 1.3 1.6 1.6 0.4 0.4 0.5 0.8 0.9 1.1 1.2
Trunk predicted mass 0.5 2.6 15.4 -0.7 0.6 1.1 1.1 3.1 1.7 0.8 1.3 -1.1 -0.3 1.4 2.6 1.4 3.9 1.2 1.3 1.2 1.3 1.1 2.9 0.6 -0.8 -0.8 0.0
Standing height 0.6 5.8 51.8 -2.1 -1.3 0.2 -0.3 5.0 1.1 0.7 1.7 0.5 -2.3 0.4 2.4 1.2 7.2 -0.7 -0.3 -0.1 0.6 -0.1 2.0 -1.0 -4.1 -3.9 -0.4
Length of working week for main job 0.5 0.6 5.1 0.6 0.1 0.9 0.5 0.5 -0.1 -0.2 1.8 -0.2 0.4 0.5 0.0 0.7 2.3 0.5 0.4 0.7 0.3 0.9 -0.0 0.1 -0.8 -0.2 -0.4
Exposure to tobacco smoke at home 0.3 0.4 3.6 0.2 0.0 0.2 0.3 1.2 -0.2 0.1 1.9 -0.2 -0.5 -0.1 0.6 0.1 1.3 0.1 0.3 0.5 0.5 0.2 0.3 0.0 -0.8 -0.4 -0.1
Breastfed as a baby 0.2 0.3 2.2 -0.0 -0.1 0.3 0.3 0.4 0.2 -0.2 1.5 -0.4 1.0 0.2 0.2 0.9 0.7 0.1 -0.0 -0.2 0.5 0.3 1.1 0.4 -0.0 -0.2 0.5
Tense / ‘highly strung’ 4.2 7.0 12.0 -3.0 -2.9 -2.8 -2.7 -1.3 -3.3 -1.3 -2.3 2.6 -2.6 -3.1 -0.9 -3.4 -1.2 -2.8 -2.9 -2.8 -2.5 -3.5 -2.3 -2.9 -2.8 -2.6 -2.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.7 3.0 0.1 -0.1 -0.4 -0.4 -1.4 -1.0 -0.3 -1.4 0.4 -0.6 -1.1 -1.0 -1.4 -1.7 -0.4 -1.2 -1.2 0.2 -0.2 -0.5 -0.1 0.5 0.6 -0.9
Hair/balding pattern: Pattern 4 0.2 0.5 4.9 -1.0 0.1 -0.4 -0.5 0.5 -0.3 -0.6 2.2 0.3 0.7 -0.5 0.1 -0.2 0.4 -0.5 -0.3 -0.4 0.3 -0.2 1.0 -0.2 -0.5 -0.8 -0.4
Birth weight of first child 6.2 11.3 18.8 2.7 3.6 3.5 3.8 3.8 3.4 3.4 1.6 -4.0 1.6 3.9 4.3 2.2 1.1 4.2 4.1 4.0 2.9 3.5 2.9 3.7 3.5 3.2 3.0
Peak expiratory flow (PEF) 1.5 3.6 8.8 -1.1 -1.3 -2.2 -1.9 -2.2 -1.8 -1.6 -2.5 1.7 -1.8 -2.3 -2.4 -2.7 -3.0 -1.4 -1.2 -1.6 -2.2 -1.8 -1.8 -1.8 -0.3 -0.4 -2.0
Pulse wave reflection index 0.6 0.8 2.0 -1.4 -0.4 -0.8 -1.0 -0.4 -0.8 -1.1 -0.9 1.0 1.0 0.4 0.2 -0.2 0.6 -0.9 -1.2 -1.1 -0.8 -0.4 0.4 -1.0 -1.0 -1.2 -1.1
Ever highly irritable/argumentative for 2 days 0.7 0.9 3.0 -0.3 -0.9 -0.7 -0.8 -0.7 -1.2 -0.7 -0.9 0.9 -0.1 -1.1 -0.6 -1.0 -1.0 -1.1 -1.1 -0.9 -1.0 -1.6 -1.7 -0.9 -0.8 -0.6 0.1
Loud music exposure frequency 1.1 1.2 2.0 -1.2 -1.4 -1.1 -1.2 -1.2 -0.8 -0.8 -0.6 1.1 -0.8 -1.3 -1.4 -1.4 -0.4 -1.2 -1.0 -1.2 -1.1 -1.0 -0.6 -1.2 -1.0 -1.1 -1.2
Qualifications: O levels/GCSEs or equivalent 0.5 0.8 3.1 1.8 0.5 0.9 0.8 -0.4 1.4 0.5 -1.0 -0.6 -0.8 0.7 -1.1 0.4 -0.7 0.6 0.8 0.7 0.6 0.5 -1.0 0.8 1.0 1.1 1.7
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 3.4 1.8 0.6 0.9 1.0 -0.6 0.2 0.4 0.7 -0.8 -0.1 -0.0 -1.0 1.2 -0.1 0.5 0.4 0.4 0.7 0.3 -0.7 0.7 0.4 0.8 1.5
Blood clot in the leg (DVT) 0.5 0.7 2.3 -0.9 -0.9 -0.5 -0.8 1.5 -0.2 -0.6 0.8 0.9 0.0 -0.6 0.6 1.2 1.3 -0.8 -0.8 -0.6 -0.4 -0.6 -0.2 -0.7 -1.3 -1.1 -0.3
Medication: Paracetamol 0.7 1.1 3.8 -0.6 -1.4 -0.7 -0.9 -1.1 -0.6 -0.5 -0.0 1.2 -1.2 -0.3 -0.8 0.2 1.5 -1.3 -1.1 -0.8 -1.0 -0.7 -1.0 -1.3 -1.9 -1.8 -0.1
Headache pain in last month 0.1 0.2 2.3 0.3 0.3 0.1 -0.0 0.1 0.4 -0.1 0.9 0.2 1.5 -0.0 -0.1 0.9 -0.0 -0.0 -0.3 -0.2 -0.3 -0.2 -0.5 0.3 0.3 0.3 0.7
Medication for cholesterol, blood pressure or diabetes 0.1 0.1 0.6 0.0 0.0 -0.2 0.1 0.0 0.6 0.8 -0.3 -0.2 0.1 0.5 0.1 0.6 -0.7 0.0 -0.1 -0.0 0.0 -0.0 0.4 0.1 0.5 0.2 -0.1
Glaucoma (self-reported) 0.8 1.0 2.6 -0.9 -1.0 -0.8 -0.9 0.6 -1.5 -0.8 -0.1 1.0 -1.0 -1.6 -0.1 -0.4 0.7 -1.2 -1.2 -0.9 -0.4 -1.4 -0.5 -1.0 -1.6 -1.4 -0.2
Gout (self-reported) 0.9 1.3 7.0 -1.1 -0.5 -1.4 -1.0 -2.6 -0.5 -0.7 -2.3 0.8 0.1 0.3 -1.4 -1.7 -1.8 -0.7 -0.5 -0.5 -1.4 -0.7 -0.0 -0.7 0.7 -0.1 -0.0
Hypothyroidism/myxoedema (self-reported) 8.6 16.7 26.9 4.0 4.7 4.6 4.8 3.6 3.7 4.3 3.7 -4.6 2.2 4.2 5.1 3.2 2.6 4.9 4.9 5.2 3.9 4.1 3.2 4.3 3.0 3.7 3.8
Medication: Amlodipine 0.2 0.3 1.4 0.7 -0.2 0.1 -0.1 0.5 -0.7 0.0 0.2 0.2 -1.2 -1.2 -0.5 -0.2 -0.9 0.1 0.3 0.3 -0.5 -0.9 -1.1 -0.1 0.2 0.5 0.5
Medication: Ventolin 100micrograms inhaler 1.9 2.5 10.3 0.6 1.1 1.3 1.3 3.2 0.7 0.4 2.1 -1.3 3.1 1.6 1.7 2.6 2.2 1.3 0.8 0.6 1.1 1.5 1.1 1.2 0.3 0.4 0.7
Birth weight 0.3 0.8 5.5 -0.9 -0.5 -0.3 -0.5 -0.0 0.3 -1.1 -0.5 0.6 1.6 0.1 0.1 0.2 2.3 -0.5 -0.4 -0.2 -0.2 0.3 0.7 -0.6 -1.4 -1.4 -1.1
Chronic bronchitis/emphysema (mother) 0.3 0.3 2.9 0.4 -0.1 0.5 0.4 -0.8 0.9 0.0 1.0 -0.3 0.3 0.2 -0.6 0.0 1.7 0.3 0.5 0.4 0.2 0.5 -0.2 0.3 -0.4 -0.2 0.7
High blood pressure (siblings) 0.2 0.3 1.2 0.8 -0.3 0.4 0.4 -0.2 -0.4 0.8 0.3 -0.3 -0.9 -0.5 0.3 -0.6 -0.9 0.1 0.1 0.3 0.1 -0.7 -1.0 0.2 0.3 0.5 1.1
Forced vital capacity (FVC), Best measure 0.6 2.2 7.2 0.3 1.2 1.2 1.5 1.2 2.0 1.8 -0.3 -1.7 -1.1 1.4 1.6 1.6 1.8 1.6 1.7 1.2 1.9 1.8 2.7 1.5 0.8 0.5 1.1
Body fat percentage 0.1 0.6 3.5 1.1 0.0 0.2 0.4 -1.9 0.3 -0.3 0.4 -0.3 0.2 -0.6 -1.5 -0.9 -0.9 0.3 0.9 0.9 -0.4 -0.4 -0.9 0.0 0.5 0.7 1.1
Leg fat percentage (right) 0.4 1.4 8.1 -0.2 -0.8 -1.0 -0.8 -2.8 -0.9 -1.2 -0.3 0.8 -0.3 -1.7 -2.0 -1.8 -1.8 -0.8 -0.3 -0.4 -1.2 -1.5 -1.4 -0.9 -0.1 -0.2 0.1
Arm fat-free mass (right) 0.2 1.1 10.2 -0.9 -0.1 0.4 0.5 1.6 1.1 0.2 0.5 -0.5 -0.0 0.7 1.3 0.6 3.2 0.5 0.8 0.8 0.4 0.4 1.7 -0.1 -1.1 -1.2 -0.3
Exposure to tobacco smoke outside home 0.2 0.3 1.4 -0.8 -0.1 0.0 0.3 0.7 -0.1 -0.0 0.4 -0.4 0.4 0.2 1.1 -0.6 1.0 0.1 0.1 0.0 0.4 0.2 1.2 0.0 -0.6 -0.5 -0.9
Comparative body size at age 10 2.2 6.0 13.9 3.7 3.2 2.5 2.8 -0.9 2.4 1.3 1.2 -2.8 1.5 1.5 -0.6 1.8 -1.6 2.9 2.9 2.8 2.1 2.3 0.9 3.0 3.6 3.7 2.9
Number of full brothers 0.4 0.5 2.2 -0.7 -1.0 -0.6 -0.7 -1.5 -0.4 0.1 -0.7 0.7 0.1 -0.7 -0.3 -0.4 -0.5 -0.8 -0.9 -0.9 -0.3 -0.6 -1.0 -0.7 -0.6 -0.7 -0.9
Worry too long after embarrassment 1.0 1.7 5.6 -0.5 -1.3 -1.2 -1.1 -1.2 -1.9 -0.3 -0.9 1.1 -2.4 -2.1 -1.3 -1.7 -1.3 -1.3 -1.4 -1.3 -0.6 -1.1 -1.7 -1.0 -1.0 -0.6 -1.1
Seen a psychiatrist for nerves, anxiety, tension or depression 5.8 7.5 18.1 -2.5 -2.6 -3.3 -3.1 -1.1 -2.9 -2.1 -4.2 3.0 -1.2 -3.1 -3.0 -3.0 -2.1 -3.0 -3.0 -3.0 -2.6 -2.9 -2.5 -3.0 -1.8 -2.2 -2.6
Wheeze or whistling in the chest in last year 0.6 1.1 2.8 1.2 0.9 1.2 0.9 1.6 0.3 1.1 1.5 -0.7 1.7 0.7 1.4 0.9 0.9 1.1 0.9 0.8 0.2 0.7 -0.8 0.8 0.5 0.8 1.2
Number of children fathered 0.8 0.9 2.3 -0.3 -0.7 -0.5 -0.6 -0.7 -1.1 -0.9 -0.8 0.8 1.0 -1.5 -1.4 -0.9 0.5 -0.9 -1.1 -0.9 -0.9 -1.1 -1.1 -0.8 -1.3 -0.9 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 2.0 -0.9 -0.8 -0.6 -0.7 -0.7 -1.0 -0.8 -0.0 0.8 -0.5 -1.0 -0.8 -0.3 0.9 -0.8 -0.8 -0.8 -0.6 -0.8 -0.4 -0.8 -1.4 -1.2 -0.7
Age at first live birth 0.3 0.5 2.6 1.2 0.3 0.5 0.7 0.8 0.5 1.1 0.2 -0.7 0.3 -0.1 0.0 -0.0 -0.8 0.5 0.4 0.4 0.3 0.0 -0.5 0.6 1.1 0.9 1.6
Pulse wave peak to peak time 0.3 0.3 2.1 -0.8 -0.3 -0.3 -0.3 -0.4 0.8 -0.7 0.4 0.3 -1.5 -0.2 -0.1 -0.1 0.8 -0.4 -0.4 -0.5 0.1 -0.1 0.4 -0.2 -0.8 -0.8 -0.8
Health satisfaction 0.4 0.6 2.7 0.0 -1.0 -0.4 -0.2 -0.1 -1.0 0.1 -0.4 0.5 1.3 -1.0 -0.3 -0.7 0.3 -0.4 -0.6 -0.6 -1.3 -0.7 -1.7 -0.7 -0.6 -0.4 -0.6
Shortness of breath walking on level ground 0.3 0.3 2.2 0.3 -0.5 -0.2 -0.3 0.3 -0.5 -0.5 0.7 0.5 1.0 -0.5 -0.3 0.2 0.1 -0.4 -0.4 -0.2 -1.0 -0.7 -1.5 -0.6 -0.4 -0.4 -0.0
Qualifications: College or University degree 1.1 3.5 12.2 3.5 1.4 2.4 2.3 0.3 2.5 1.4 2.2 -1.9 1.2 1.2 -0.5 2.0 1.1 1.9 1.5 1.2 1.7 1.9 -0.7 2.1 1.5 2.1 2.7
Eye problems/disorders: None of the above 1.0 1.2 9.4 -0.6 -0.8 -0.9 -0.9 -3.1 -0.4 -1.6 -0.1 0.9 0.8 -0.3 -1.7 -1.1 -0.1 -0.8 -0.7 -0.9 -1.1 -0.1 -1.2 -0.9 -0.6 -0.8 -1.3
Mouth/teeth dental problems: Loose teeth 0.7 0.9 6.8 0.3 0.3 0.9 0.7 1.0 0.3 0.1 1.8 -0.5 0.9 0.8 1.3 1.2 2.6 0.5 0.5 0.8 0.7 0.9 0.7 0.5 -0.8 -0.5 -0.3
Emphysema/chronic bronchitis 0.1 0.2 0.7 -0.2 -0.4 -0.3 -0.2 0.1 -0.5 -0.6 -0.6 0.3 0.2 0.1 -0.3 -0.1 -0.7 -0.2 -0.4 -0.1 -0.5 0.0 -0.8 -0.4 0.0 -0.2 -0.6
Medication for pain relief, constipation, heartburn 0.6 1.1 2.9 0.9 1.0 0.9 1.0 1.1 1.0 0.5 0.2 -1.2 0.8 1.1 1.2 0.9 -0.6 1.2 1.1 1.0 1.0 1.0 1.3 1.3 1.7 1.5 0.7
Neck or shoulder pain in last month 2.6 3.6 7.8 2.8 1.3 2.4 2.3 1.9 2.1 2.2 2.5 -1.9 2.5 1.4 0.5 1.7 2.4 2.0 1.6 1.9 1.2 1.9 0.1 1.9 0.7 1.5 2.2
Medication: Blood pressure 0.3 0.5 1.3 0.6 0.7 1.0 0.9 0.3 0.4 0.4 0.8 -0.9 0.3 0.3 0.8 0.6 0.7 1.0 1.1 0.9 0.6 0.8 0.7 0.8 0.7 0.5 1.0
Angina (self-reported) 0.4 0.6 1.6 -1.1 -0.3 -0.5 -0.8 -0.0 -0.6 -0.8 0.4 0.8 0.7 -1.0 -0.5 0.2 1.0 -0.9 -1.0 -1.3 -0.5 -0.7 -0.1 -0.7 -1.1 -1.1 -0.2
Migraine (self-reported) 0.4 0.5 2.8 -0.9 0.1 -0.2 -0.3 -1.4 0.9 -0.3 -0.5 0.3 0.9 0.8 -0.2 -0.8 1.7 0.1 -0.4 -0.8 -0.6 0.7 0.8 -0.1 -0.4 -0.6 -1.0
Medication: Ibuprofen 0.3 0.4 3.5 0.2 0.2 0.3 0.2 0.9 0.1 0.3 -0.0 -0.0 1.0 0.2 -0.8 1.0 1.9 0.1 0.3 0.2 -0.1 0.2 0.1 -0.1 -0.9 -0.5 0.2
Medication: Allopurinol 2.1 2.9 7.1 -2.1 -1.3 -2.1 -2.1 -2.7 -1.6 -2.0 -2.3 1.9 -0.6 -0.6 -1.8 -1.8 -1.0 -1.8 -1.6 -1.3 -2.2 -1.7 -0.7 -1.8 -0.9 -1.5 -0.8
Medication: Omeprazole 1.3 1.6 7.4 -2.1 -1.3 -0.9 -1.2 -0.2 0.1 -0.9 0.6 1.1 0.2 -0.0 0.2 -0.8 2.7 -1.3 -1.0 -0.9 -0.5 -0.3 0.5 -1.2 -2.2 -2.7 -1.2
Medication: Seretide 50 evohaler 0.2 0.3 3.0 0.1 0.0 0.3 0.4 0.1 -0.1 -0.2 1.2 -0.4 1.7 0.2 0.7 0.7 0.3 0.4 0.3 0.2 -0.1 0.4 0.0 0.1 0.2 0.2 -0.2
Mean time to correctly identify matches 1.3 2.4 7.7 0.3 1.2 1.6 1.6 1.6 1.2 1.2 2.6 -1.7 1.6 1.7 2.8 1.7 2.0 1.4 1.3 1.3 1.6 1.3 1.8 1.5 0.6 0.3 1.2
Heart disease (mother) 4.5 5.5 11.0 3.1 2.5 2.6 2.7 2.6 1.5 2.7 3.3 -2.6 1.5 1.3 2.3 1.6 -0.6 2.3 2.3 2.4 2.4 1.2 0.8 2.7 2.4 2.9 3.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 3.9 -1.1 -1.0 -0.8 -0.9 -2.0 -1.2 -0.9 -1.3 0.8 -1.2 -0.4 -0.8 -1.6 0.2 -0.9 -1.0 -1.0 -0.8 -0.5 0.2 -0.8 -0.7 -0.9 -0.5
Whole body fat mass 0.1 0.4 1.6 0.8 0.2 0.6 0.7 -0.6 0.8 0.1 0.8 -0.6 0.1 -0.1 -0.6 -0.3 0.4 0.7 1.2 1.2 0.0 -0.1 0.1 0.3 0.2 0.4 1.1
Leg fat mass (right) 0.1 0.2 1.4 0.2 -0.1 -0.0 0.1 -1.2 0.3 -0.4 0.3 -0.1 -0.2 -0.7 -1.0 -0.7 -0.2 0.1 0.7 0.7 -0.4 -0.7 -0.1 -0.2 -0.0 0.1 0.6
Arm predicted mass (right) 0.2 1.3 8.7 -0.8 0.3 0.6 0.7 1.8 1.3 0.4 0.5 -0.8 -0.1 0.9 1.6 0.8 3.0 0.9 1.0 1.0 0.7 0.7 2.3 0.2 -0.8 -0.8 -0.4
Pulse rate, automated reading 1.6 5.0 8.2 -2.0 -2.6 -2.5 -2.6 -2.0 -1.6 -2.0 -1.3 2.7 -0.2 -2.9 -2.7 -1.9 -0.5 -2.7 -2.3 -2.5 -2.2 -2.4 -2.3 -2.7 -2.6 -2.3 -2.1
Alcohol intake frequency. 0.2 0.4 2.2 -0.7 0.2 -0.3 -0.2 0.6 -0.4 0.5 -0.6 0.1 1.5 0.6 1.4 -0.3 -0.8 0.1 0.5 0.7 -0.6 -0.4 0.5 -0.2 0.6 0.2 -0.5
Comparative height size at age 10 0.8 4.4 23.4 -2.7 -1.7 -0.9 -1.4 3.5 0.0 -0.8 1.6 1.5 -3.0 -0.2 1.5 -0.4 4.8 -1.5 -0.9 -0.7 -0.7 -0.9 0.8 -1.7 -3.7 -3.8 -1.9
Number of full sisters 0.5 0.6 3.8 -0.7 -0.6 -0.1 -0.6 -0.0 0.3 -0.6 -0.5 0.7 -0.8 -0.0 -0.7 -0.5 2.0 -0.7 -0.8 -0.8 -0.2 -0.2 0.5 -0.6 -1.3 -1.3 0.1
Suffer from ‘nerves’ 3.4 5.4 9.5 -1.9 -2.0 -2.3 -2.4 -2.2 -2.7 -1.0 -2.0 2.5 -2.7 -3.1 -2.1 -3.0 -1.0 -2.6 -2.7 -2.6 -1.9 -2.6 -2.3 -2.3 -2.4 -2.0 -2.1
Overall health rating 0.2 0.4 1.1 -0.1 -0.5 0.0 -0.1 0.7 -0.5 0.4 0.4 0.4 0.6 -0.7 0.8 -0.1 1.0 -0.3 -0.6 -0.3 -0.6 -0.3 -1.1 -0.6 -1.0 -0.6 -1.0
Chest pain or discomfort 1.3 1.8 5.0 1.2 1.3 1.4 1.4 1.6 1.0 1.5 1.8 -1.3 2.2 1.3 1.6 1.3 0.4 1.4 0.7 0.9 1.5 1.8 0.7 1.5 1.3 1.2 0.8
Had major operations 0.8 1.0 2.9 1.0 1.0 1.0 1.0 -0.1 0.1 0.6 1.2 -1.1 1.5 0.4 0.7 0.4 -0.1 1.3 1.7 1.4 1.0 0.9 1.0 1.0 0.9 1.2 0.8
Age at last live birth 0.1 0.2 1.1 0.6 -0.1 0.0 0.2 0.0 -0.4 0.6 -1.0 -0.1 -0.6 -0.7 0.0 -0.1 -0.5 -0.1 -0.4 -0.3 0.1 -0.6 -0.4 0.1 0.2 0.3 1.0
Family relationship satisfaction 0.2 0.3 2.4 -0.1 -0.4 -0.2 -0.2 -0.1 -0.5 -0.3 -0.1 0.3 1.6 0.6 -0.5 -0.7 -0.4 0.0 0.2 0.3 -1.1 -0.0 -0.6 -0.4 0.3 0.0 -0.5
Leg pain on walking 0.1 0.2 0.7 0.4 0.1 0.4 0.4 0.8 0.2 0.3 0.1 -0.4 0.1 -0.1 0.6 0.7 0.6 0.3 0.0 0.3 0.4 -0.2 0.3 0.3 0.1 0.1 0.8
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 2.9 0.2 -0.5 -0.4 -0.5 -0.7 -1.7 -0.5 0.1 0.6 -0.9 -1.0 -1.1 -0.3 -0.4 -0.7 -0.7 -0.6 -0.6 -1.0 -1.1 -0.6 -0.7 -0.2 -0.1
Commuting to job workplace: Car/motor vehicle 0.8 0.9 3.1 -0.4 -1.3 -0.9 -1.1 -0.5 -0.7 -1.1 0.2 1.2 -1.8 -1.1 -0.8 -0.5 -0.4 -1.1 -0.5 -0.4 -1.2 -1.2 -1.3 -1.1 -0.9 -0.9 0.1
Illness, injury, bereavement, stress in last 2 years 1.2 1.5 3.5 -1.9 -1.4 -1.5 -1.4 -1.0 -0.8 -1.4 -1.3 1.3 -1.8 -1.0 -0.5 -0.6 0.4 -1.2 -0.7 -0.7 -1.0 -0.9 0.6 -1.3 -1.5 -1.4 -1.8
Medication: Aspirin 2.1 2.7 5.0 -1.5 -1.2 -1.5 -1.7 -2.2 -1.8 -1.9 -0.6 1.8 -0.0 -2.2 -1.9 -1.8 -0.9 -1.7 -1.6 -1.6 -1.8 -1.9 -2.0 -1.8 -1.5 -1.4 -1.6
Supplements: Vitamin C 0.2 0.2 1.2 -0.8 -0.3 -0.2 -0.3 -0.3 0.2 0.3 0.5 0.2 0.5 -0.2 0.6 0.4 -0.1 -0.4 -1.1 -0.9 -0.0 -0.2 0.3 -0.2 -0.3 -0.4 -0.9
Knee pain experienced in last month 0.3 0.5 1.5 -0.5 -1.2 -0.6 -0.6 0.6 -0.5 -0.2 -0.5 0.7 -0.4 -0.9 -0.2 0.2 1.0 -0.6 -0.3 -0.3 -1.0 -0.8 -0.8 -0.8 -1.1 -1.1 -0.3
Hypertension (Self-reported) 1.0 2.8 6.8 1.4 1.7 2.2 2.0 1.4 1.1 1.6 2.6 -1.9 0.8 1.3 2.1 1.1 1.6 1.9 2.0 1.9 1.9 1.2 1.3 1.7 0.7 1.0 2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.5 7.2 0.2 0.7 1.1 1.0 0.7 1.8 0.9 1.3 -1.0 -0.3 1.3 1.8 1.4 2.7 0.9 1.3 1.3 1.7 1.4 1.7 0.8 -0.5 -0.5 0.9
Illnesses of father: Heart disease 1.9 2.6 5.9 2.2 1.6 1.9 2.0 0.9 0.8 2.1 1.2 -2.0 1.1 1.5 1.3 1.0 -0.6 2.0 1.6 1.5 1.6 1.4 0.8 1.9 1.9 2.4 1.9
Illnesses of siblings: Diabetes 0.5 0.6 4.1 -0.6 -0.7 -0.8 -0.8 -0.6 -2.0 -0.3 -0.1 0.7 0.4 -0.7 -0.9 -0.4 -0.9 -0.7 -0.8 -0.6 -1.1 -1.0 -0.7 -0.9 -0.2 -0.5 -0.2
Smoking status: Previous 1.0 1.6 5.8 -1.4 -1.1 -1.1 -1.1 -2.4 -1.2 -0.8 -0.2 0.9 -1.7 -1.1 -1.6 -1.8 0.1 -1.0 -1.8 -2.0 -0.4 -0.5 0.1 -0.8 -1.0 -1.0 -1.5
Forced expiratory volume in 1-second (FEV1), predicted 1.7 3.6 7.7 -2.1 -2.0 -1.9 -2.1 -0.4 -1.1 -2.1 -2.3 2.2 -1.5 -1.6 -1.7 -1.0 1.3 -2.2 -2.0 -2.1 -1.5 -1.6 -0.9 -2.2 -2.8 -2.7 -1.9
Whole body fat-free mass 0.6 3.5 15.2 -0.0 1.1 1.6 1.6 3.0 2.2 1.2 1.6 -1.7 0.1 1.9 2.7 1.8 3.9 1.8 2.0 2.0 1.5 1.5 3.1 1.1 -0.3 -0.2 0.6
Leg fat-free mass (right) 1.1 6.1 15.8 1.1 2.0 2.5 2.6 3.4 2.8 1.9 2.2 -2.6 0.8 2.7 3.0 2.4 4.0 2.7 3.0 3.1 2.1 2.2 3.4 2.0 0.5 0.8 1.6
Arm fat percentage (left) 0.5 2.0 5.6 2.4 1.2 1.4 1.7 -1.2 1.2 0.6 0.7 -1.5 0.8 0.3 -0.8 -0.1 -1.3 1.6 2.0 2.0 0.6 0.6 -0.2 1.3 1.9 2.2 2.1
Average weekly red wine intake 0.3 0.4 2.5 -0.2 -0.3 -0.1 -0.3 0.3 -0.2 -1.4 1.2 0.4 -0.3 0.0 -0.6 0.4 1.6 -0.5 -0.8 -0.8 -0.1 0.1 -0.1 -0.3 -1.1 -1.0 -0.0
Handedness (chirality/laterality): Left-handed 1.3 1.5 6.4 1.5 1.5 0.8 1.0 -0.2 0.9 0.7 -0.4 -1.1 0.4 0.4 0.7 0.1 -2.5 1.3 1.0 0.9 0.8 0.6 0.4 1.4 2.4 2.5 1.1
Mood swings 2.3 4.2 8.1 -2.1 -1.8 -2.4 -2.2 -1.3 -2.8 -1.6 -1.7 2.2 -0.7 -2.4 -1.3 -2.5 -1.1 -2.2 -2.2 -2.2 -2.0 -2.3 -1.8 -2.3 -1.9 -1.8 -2.7
Loneliness, isolation 1.3 1.9 5.3 -1.4 -1.1 -1.5 -1.4 -1.7 -2.3 -0.4 -1.9 1.2 -1.1 -1.6 -0.9 -1.9 -0.9 -1.2 -1.3 -1.4 -1.3 -1.4 -0.2 -1.3 -0.9 -1.0 -1.6
Long-standing illness, disability or infirmity 0.9 1.3 5.2 1.5 1.0 1.6 1.4 0.9 -0.3 1.6 2.3 -1.2 0.9 0.7 1.4 0.5 0.6 1.2 0.7 1.4 0.8 0.7 -0.0 1.1 0.6 1.1 1.6
Ever had bowel cancer screening 0.3 0.3 1.1 -0.3 -0.5 -0.4 -0.4 -1.1 -0.4 -0.2 -0.1 0.3 0.4 -0.3 -0.8 -0.8 -0.6 -0.3 -0.7 -0.8 -1.0 -0.4 -0.7 -0.5 0.4 -0.2 -0.1
Diabetes diagnosed by doctor 0.2 0.4 2.2 0.9 0.5 0.6 0.4 0.4 -0.2 -0.1 1.5 -0.2 1.0 0.3 -0.5 -0.0 -0.2 0.4 0.7 0.9 -0.0 0.4 -1.2 0.2 0.4 0.5 0.3
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 2.2 1.2 1.2 1.1 1.2 0.4 1.1 1.0 0.5 -1.1 0.1 0.9 0.5 0.5 0.7 1.1 1.3 1.5 0.7 0.9 0.1 0.9 0.8 0.7 1.2
Friendships satisfaction 2.8 3.5 6.7 -1.8 -2.0 -2.1 -2.1 -1.7 -2.6 -2.1 -0.6 2.0 0.5 -1.7 -2.1 -1.8 -1.5 -2.0 -2.1 -2.2 -2.2 -2.0 -1.7 -2.0 -1.2 -1.6 -2.0
Qualifications: nursing, teaching 0.3 0.5 3.2 1.5 0.2 0.7 0.6 0.6 0.5 0.5 -0.0 -0.4 -0.3 0.0 -0.7 1.2 -0.3 0.6 0.5 0.8 0.1 -0.2 -0.4 0.5 0.7 0.9 1.8
Commuting to job workplace: Walk 2.2 2.4 4.0 1.6 1.3 1.8 2.0 0.4 1.7 1.7 1.0 -1.9 1.8 1.2 0.5 1.8 0.7 1.8 1.5 1.6 1.7 1.5 1.3 1.8 1.4 1.6 1.8
Eye problems/disorders: Cataract 0.9 1.1 6.7 -0.1 0.5 0.6 0.6 2.6 0.1 1.2 0.5 -0.8 -0.9 0.7 2.6 0.9 0.0 0.8 0.7 0.6 1.0 0.3 1.8 0.8 0.6 0.7 0.5
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 4.2 -0.6 -1.1 -1.4 -1.4 0.3 -1.3 -1.0 -1.1 1.4 -0.4 -1.3 -1.6 -0.5 -1.4 -1.4 -1.8 -2.0 -1.1 -0.9 -1.4 -1.1 -0.4 -0.4 -1.2
Medication for cholesterol 0.3 0.5 2.3 -0.5 -0.5 -0.6 -0.5 -1.3 -0.5 -0.7 -1.5 0.4 0.6 -1.0 -1.0 -0.2 -0.1 -0.6 -0.9 -1.1 -0.5 -0.4 -0.1 -0.5 -0.5 -0.5 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.6 3.1 6.8 1.6 1.8 2.0 1.9 2.2 2.1 2.6 1.9 -1.8 0.5 1.7 1.9 1.5 0.4 1.7 1.7 2.0 2.1 1.4 1.3 1.8 1.4 1.5 2.0
Back pain experienced in last month 1.0 1.5 3.7 -0.7 -1.7 -1.1 -1.1 1.4 -1.9 -1.0 0.6 1.4 -0.1 -0.9 -0.2 -0.3 0.5 -1.4 -1.7 -1.3 -1.3 -1.2 -1.8 -1.4 -1.7 -1.4 -1.1
Mineral and other dietary supplements 2.1 2.8 6.5 -1.7 -1.4 -1.7 -1.8 -1.3 -2.0 -2.6 -1.7 1.9 0.4 -1.4 -1.5 -1.4 0.6 -1.9 -1.9 -1.9 -1.4 -1.5 -1.2 -1.9 -2.2 -2.0 -1.4
Breast cancer (self-reported) 0.7 0.9 4.9 -0.8 -1.0 -0.8 -0.8 -2.2 0.0 -0.9 -0.8 0.8 -0.0 -0.8 -1.4 -0.9 -0.6 -0.9 -1.0 -0.6 -1.1 -1.0 -0.4 -1.0 -0.6 -0.8 -0.6
Asthma (self-reported) 1.0 1.9 8.0 0.9 0.9 1.5 1.3 2.5 0.5 0.6 1.5 -1.1 1.4 1.6 2.0 2.1 2.8 1.4 1.1 0.8 1.0 1.4 0.9 1.1 -0.1 0.4 0.8
Osteoporosis (self-reported) 3.2 4.0 7.5 -2.2 -2.3 -2.1 -2.6 -1.6 -2.3 -2.0 -2.7 2.6 -0.8 -1.5 -1.0 -1.6 -0.4 -2.3 -2.2 -2.0 -2.2 -1.8 -1.4 -2.3 -2.0 -2.0 -2.3
Osteoarthritis (self-reported) 1.6 2.0 7.0 1.3 1.2 1.7 1.4 1.6 1.4 1.1 2.6 -1.1 1.7 1.7 1.7 1.7 2.6 1.5 0.9 1.2 0.5 1.6 0.3 1.0 0.0 0.3 0.6
Medication: Aspirin 1.6 2.0 4.7 -1.1 -1.0 -1.2 -1.4 -1.9 -1.7 -1.8 -0.3 1.5 0.2 -2.2 -1.7 -1.6 -1.0 -1.4 -1.2 -1.1 -1.6 -1.8 -2.0 -1.5 -1.1 -1.0 -1.0
Medication: Gliclazide 0.2 0.2 1.2 0.0 -0.5 -0.1 -0.1 -0.3 0.1 -0.2 0.4 0.3 0.3 -0.2 -1.1 0.1 0.9 -0.3 0.5 0.4 -0.5 -0.3 -0.3 -0.4 -0.8 -0.5 0.1
Illnesses of father: None of the above (group 1) 0.1 0.1 0.7 -0.6 -0.0 -0.3 -0.4 0.2 0.4 -0.8 -0.4 0.3 0.1 0.6 0.2 -0.1 0.4 -0.2 -0.1 -0.0 0.1 0.2 0.8 -0.1 -0.1 -0.5 -0.5
Smoking status: Current 0.6 1.0 3.7 0.9 0.8 1.1 0.9 1.2 1.1 1.1 1.0 -0.7 0.2 0.4 1.6 1.2 1.0 0.5 1.4 1.9 0.6 -0.2 -0.4 0.5 -0.1 0.0 1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 2.3 0.0 0.6 -0.0 0.2 -1.5 0.5 -0.3 -0.2 -0.4 0.4 -0.3 -0.1 0.0 -0.6 0.5 0.5 0.0 -0.1 0.1 0.5 0.3 0.7 0.4 0.2
Whole body water mass 0.6 3.4 15.3 -0.1 1.0 1.6 1.6 3.0 2.1 1.2 1.6 -1.7 0.3 1.9 2.6 1.8 3.9 1.8 2.0 2.0 1.5 1.5 3.1 1.1 -0.3 -0.2 0.6
Leg predicted mass (right) 1.1 6.0 15.9 1.0 2.0 2.5 2.6 3.3 2.8 1.9 2.2 -2.5 0.7 2.7 3.0 2.5 4.0 2.7 3.0 3.1 2.1 2.2 3.4 1.9 0.5 0.7 1.6
Arm fat mass (left) 0.3 1.4 4.0 1.6 1.0 1.3 1.5 -0.4 1.4 0.6 0.8 -1.5 0.6 0.6 -0.1 0.3 0.0 1.6 2.0 2.0 0.6 0.7 0.6 1.1 1.2 1.5 1.6
Number of self-reported non-cancer illnesses 0.5 0.9 9.6 0.0 -0.0 0.7 0.5 1.4 -0.1 0.6 1.3 -0.2 0.4 0.6 1.5 0.5 3.1 0.4 0.6 0.7 0.1 0.2 0.1 0.0 -1.3 -0.9 0.7
Average weekly champagne plus white wine intake 3.4 4.7 8.3 -1.4 -2.4 -2.2 -2.2 -1.8 -1.6 -2.2 -2.5 2.2 -2.7 -2.8 -2.3 -2.1 -2.4 -2.4 -2.3 -2.1 -1.8 -2.9 -2.2 -2.0 -1.1 -1.3 -1.4
Miserableness 2.1 3.6 8.0 -2.1 -1.9 -2.3 -2.1 -0.8 -2.5 -1.1 -1.8 2.0 -0.5 -1.9 -0.6 -2.8 -1.8 -1.9 -1.9 -1.8 -2.3 -2.2 -2.0 -2.2 -1.1 -1.4 -2.4
Guilty feelings 1.4 2.1 6.3 -1.2 -1.4 -1.6 -1.5 -1.9 -1.8 -1.0 -1.8 1.3 -2.5 -1.7 -1.3 -2.0 -1.8 -1.2 -1.1 -1.0 -0.9 -1.3 -0.6 -1.1 -0.5 -0.5 -1.5
Wears glasses or contact lenses 0.5 0.5 2.9 -1.1 -0.9 -0.6 -0.4 -0.5 -1.0 -0.9 0.8 0.2 -0.0 -0.6 1.0 -1.7 -1.0 -0.2 -0.4 -0.3 -0.6 -0.6 0.1 -0.4 0.1 -0.1 -1.0
Ever taken oral contraceptive pill 0.1 0.1 0.7 -0.2 0.2 0.1 -0.2 -0.3 -0.4 -0.4 0.2 0.3 0.8 -0.1 -0.0 0.3 0.3 -0.1 0.2 0.3 0.0 0.0 -0.3 -0.3 -0.4 -0.4 -0.6
Hearing aid user 1.2 1.3 5.5 0.8 0.9 1.1 1.2 2.3 0.1 1.4 1.3 -1.1 0.3 1.2 1.8 -0.4 0.4 1.2 1.6 1.9 0.7 0.8 0.6 0.9 1.0 0.9 1.1
Mother’s age at death 0.2 0.2 0.7 0.1 0.3 0.4 0.3 0.1 0.8 0.1 0.4 -0.4 0.6 0.5 0.6 -0.2 -0.5 0.4 0.7 0.6 0.0 -0.1 0.2 0.3 0.5 0.4 0.6
Financial situation satisfaction 4.4 5.4 8.9 -2.4 -2.5 -2.6 -2.8 -1.2 -3.0 -2.7 -1.9 2.8 -0.7 -1.9 -2.5 -1.7 -1.0 -2.6 -2.9 -2.6 -2.8 -2.1 -1.7 -2.7 -2.0 -2.1 -2.6
Tinnitus: Yes, now most or all of the time 0.9 1.0 1.8 0.6 1.0 1.0 1.1 1.0 0.5 0.9 1.3 -1.2 1.3 0.6 0.9 0.9 0.3 1.2 1.3 0.8 1.3 0.8 1.3 1.1 0.8 1.0 0.9
Commuting to job workplace: Public transport 0.3 0.3 2.8 -0.0 -0.0 0.5 0.3 -0.2 0.6 0.1 0.3 -0.1 1.1 1.1 0.3 0.1 1.7 -0.0 -0.1 -0.1 0.2 0.7 -0.2 0.1 -0.7 -0.7 -0.2
Eye problems/disorders: Glaucoma 0.3 0.4 2.2 0.2 -0.6 -0.1 -0.1 0.7 -0.7 -0.1 0.1 0.3 -1.5 -1.1 -0.2 0.0 0.4 -0.5 -0.4 -0.1 0.1 -1.1 -0.7 -0.4 -1.0 -0.6 0.4
Medication: Blood pressure 0.6 1.1 6.2 0.3 0.5 1.0 0.9 1.8 0.6 1.0 2.5 -0.8 0.1 1.2 1.6 1.0 1.5 0.7 1.0 1.1 0.8 0.3 0.9 0.7 -0.1 0.0 1.3
Pain type(s) experienced in last month: Hip pain 1.7 2.2 10.6 1.0 1.0 1.7 1.2 1.4 1.4 1.1 2.7 -0.9 1.6 1.5 1.5 2.2 3.3 1.0 0.8 1.1 1.3 1.7 0.8 1.0 -0.6 -0.0 0.7
Supplements: Fish oil (including cod liver oil) 1.0 1.3 4.0 1.6 0.8 1.1 1.1 0.5 1.2 1.8 0.7 -1.2 -0.2 0.6 0.1 0.6 -1.6 1.2 1.0 1.1 0.8 0.8 0.3 1.3 2.0 1.9 0.9
High cholesterol (Self-reported) 0.9 1.6 4.6 -1.4 -1.4 -1.1 -1.3 -0.0 -2.1 -1.9 -0.2 1.3 0.4 -1.4 -0.8 -1.3 0.6 -1.3 -1.0 -1.1 -1.4 -1.4 -1.1 -1.4 -1.6 -1.7 -0.8
Medication: Bendroflumethiazide 0.5 0.7 3.1 0.1 0.2 0.7 0.8 1.3 0.9 1.3 0.8 -0.8 -1.3 0.5 1.8 0.3 0.4 0.6 1.0 0.9 0.6 0.0 1.0 0.6 0.3 0.2 1.0
Medication: Paracetamol 0.8 1.2 5.5 -0.6 -1.4 -0.6 -0.9 -0.5 -1.0 -0.6 0.7 1.1 -1.1 -0.6 -0.7 0.3 1.9 -1.3 -1.1 -0.8 -0.8 -1.0 -0.9 -1.3 -2.4 -2.0 0.1
Medication: Lisinopril 0.3 0.4 2.2 0.5 0.0 0.7 0.6 1.3 -0.4 0.5 1.5 -0.5 0.1 0.5 1.0 0.3 1.1 0.4 0.6 0.8 0.1 0.2 -0.3 0.2 -0.2 -0.2 0.3
Medication: Atorvastatin 1.2 1.5 5.9 -0.3 -0.7 -0.8 -1.2 0.1 -1.5 -2.0 -0.1 1.4 0.5 -1.9 -2.4 -0.1 0.5 -1.2 -1.2 -1.3 -1.1 -1.3 -1.6 -1.1 -1.7 -1.0 -0.2
Illnesses of father: High blood pressure 0.3 0.4 1.6 0.7 -0.5 0.2 0.2 0.4 0.1 0.9 -0.5 -0.0 -1.2 -0.7 -0.2 0.4 -0.3 -0.0 0.5 0.7 -0.0 -0.8 -1.3 -0.0 -0.2 0.1 1.0
Alcohol drinker status: Never 0.5 0.6 2.2 -1.2 -0.6 -0.9 -0.6 1.0 -1.0 0.0 -0.2 0.3 -1.5 -0.7 1.2 -1.0 -1.0 -0.5 -0.5 -0.6 -0.2 -1.3 0.5 -0.5 -0.1 -0.5 -0.2
Ever smoked 0.1 0.2 1.6 -0.1 0.3 0.3 0.3 -1.3 0.3 0.3 -0.2 -0.3 -0.6 0.1 -0.5 -0.1 0.6 0.2 -0.1 -0.2 0.6 0.3 0.4 0.3 -0.0 -0.2 0.4
Basal metabolic rate 0.5 2.7 12.5 0.1 0.9 1.4 1.5 2.5 2.0 1.0 1.5 -1.5 0.0 1.5 2.1 1.4 3.5 1.6 1.9 1.9 1.3 1.2 2.7 1.0 -0.3 -0.2 0.7
Leg fat percentage (left) 0.2 0.8 8.4 0.3 -0.3 -0.4 -0.2 -2.9 -0.4 -0.9 0.1 0.2 0.0 -0.9 -1.7 -1.2 -1.4 -0.2 0.3 0.3 -0.8 -0.8 -0.7 -0.4 0.3 0.3 0.5
Arm fat-free mass (left) 0.3 1.3 11.3 -0.8 0.1 0.5 0.6 1.9 1.1 0.3 0.8 -0.6 -0.1 0.8 1.5 0.8 3.4 0.7 0.9 0.9 0.4 0.4 2.1 0.1 -1.1 -1.1 -0.2
Number of operations (self-reported) 0.5 0.8 3.2 0.2 0.5 0.8 0.7 0.5 0.2 1.1 0.7 -0.8 0.5 0.9 1.4 1.1 1.3 0.8 1.1 0.8 1.0 0.8 1.8 0.7 0.2 0.2 0.9
Average weekly beer plus cider intake 0.5 0.7 2.0 0.4 0.6 0.8 0.8 1.0 1.1 1.1 0.5 -0.8 -0.8 0.5 1.4 1.2 1.0 0.8 1.2 1.3 1.0 0.6 0.6 0.6 -0.2 0.3 0.4
Irritability 8.6 14.5 23.4 -3.0 -3.9 -4.1 -4.0 -4.1 -3.9 -3.6 -3.1 4.1 -2.2 -4.0 -4.0 -4.8 -2.4 -4.3 -4.2 -3.9 -3.7 -3.9 -4.6 -4.2 -3.2 -3.3 -4.0
Risk taking 0.1 0.1 0.8 0.2 0.1 0.2 0.1 0.6 -0.7 -0.2 0.3 -0.1 0.5 0.1 0.1 0.9 -0.2 0.1 -0.3 -0.5 0.5 -0.0 0.4 0.2 0.2 0.4 0.2
Ever had prostate specific antigen (PSA) test 1.1 1.2 3.9 -1.2 -0.8 -1.2 -1.3 -0.7 -1.4 -1.0 -2.0 1.1 -0.8 -1.3 -0.4 -1.1 -1.5 -1.0 -1.5 -1.7 -0.4 -0.9 -0.1 -0.9 -0.3 -0.4 -1.5
Fractured/broken bones in last 5 years 3.2 4.1 5.8 -1.4 -1.8 -2.1 -2.2 -2.3 -1.8 -2.2 -2.0 2.2 -1.3 -2.3 -2.3 -2.3 -0.8 -2.2 -2.3 -2.3 -2.0 -1.6 -2.4 -2.2 -1.7 -1.8 -1.9
Age started oral contraceptive pill 0.2 0.3 3.2 -0.4 0.1 0.1 0.3 -0.3 0.1 0.4 1.8 -0.3 0.0 0.8 1.2 -0.4 -0.4 0.3 0.1 0.3 0.3 0.2 0.1 0.2 0.4 0.2 -0.5
Diastolic blood pressure, automated reading 0.8 2.4 5.6 1.5 1.0 1.8 1.6 1.7 1.6 1.8 2.0 -1.4 0.8 1.0 1.6 1.9 2.4 1.3 1.6 1.6 1.7 1.1 1.2 1.4 -0.1 0.6 2.0
Ever depressed for a whole week 0.2 0.2 2.2 0.7 -0.0 0.1 0.2 0.1 -0.3 0.4 -0.3 -0.1 -0.3 -0.2 0.1 0.1 -1.5 0.0 -0.3 -0.2 0.3 -0.7 -0.9 0.2 0.5 0.7 0.4
Unable to work because of sickness or disability 2.0 2.6 4.3 1.7 1.9 1.8 1.8 1.8 1.3 1.6 1.3 -1.8 1.2 1.6 1.4 1.3 -0.0 2.0 1.5 1.4 1.3 1.8 1.5 1.8 2.1 2.1 1.4
Commuting to job workplace: Cycle 6.4 7.7 15.4 3.2 2.5 3.3 3.3 1.9 3.9 2.9 3.6 -3.1 1.0 3.2 2.3 2.3 2.2 3.0 3.1 3.4 2.3 2.9 1.4 2.8 2.0 2.0 3.1
Myopia 0.6 0.8 4.1 -1.3 -1.0 -1.0 -0.8 -0.0 -0.9 -0.1 -0.9 0.7 -0.4 -0.1 0.2 -2.0 -0.5 -0.9 -1.6 -1.6 -0.4 -0.5 -0.1 -0.8 -0.4 -0.6 -1.2
Vascular/heart problems diagnosed by doctor 0.6 1.8 4.2 -1.3 -1.5 -1.9 -1.7 -0.8 -0.8 -1.0 -2.0 1.5 -0.9 -0.9 -1.3 -0.8 -1.4 -1.5 -1.6 -1.5 -1.5 -1.0 -0.6 -1.4 -0.4 -0.9 -2.0
Cholesterol lowering medication 0.4 0.5 3.7 -0.0 -0.0 0.4 -0.1 0.8 0.5 -0.8 1.9 0.2 1.4 0.6 -0.0 -0.1 1.9 0.1 0.3 0.4 -0.4 0.5 -0.2 -0.0 -0.6 -0.6 0.0
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 11.8 -1.4 -0.4 -0.1 -0.3 0.3 0.8 -0.5 1.5 0.3 0.4 0.4 0.9 -0.2 3.4 -0.4 0.0 -0.1 0.2 0.4 1.0 -0.4 -1.9 -2.0 -0.5
Pain experienced in last month 0.4 0.6 2.5 0.1 0.7 0.2 0.5 -1.3 0.4 0.1 -0.6 -0.8 -0.8 0.5 0.1 0.0 -1.3 0.5 0.7 0.5 1.2 0.4 1.6 0.7 1.3 1.0 0.3
Supplements: Calcium 0.2 0.2 1.1 -0.1 -0.1 -0.2 -0.2 0.9 0.1 0.4 -0.8 0.1 -0.7 0.5 0.7 -0.1 -1.1 -0.2 -0.3 -0.2 0.3 0.2 -0.1 0.0 0.3 0.1 -0.6
Basal cell carcinoma (self-reported) 3.2 3.9 8.2 -2.3 -2.3 -2.1 -2.0 0.1 -1.4 -1.6 -0.4 2.1 -0.4 -1.8 -1.5 -1.1 0.8 -2.3 -2.4 -2.5 -2.1 -1.9 -1.9 -2.5 -2.6 -2.9 -2.6
Heart attack/myocardial infarction (self-reported) 0.1 0.2 1.1 -0.6 0.2 -0.0 -0.0 0.1 -0.6 -0.2 0.4 -0.1 0.1 -0.1 0.1 -0.1 0.3 -0.1 -0.7 -0.6 0.6 0.3 1.0 0.1 -0.2 -0.2 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 1.5 -0.8 -0.7 -0.5 -0.7 1.2 -0.0 -0.6 0.9 0.8 0.1 -0.4 0.5 1.0 0.9 -0.6 -0.6 -0.4 -0.3 -0.4 -0.1 -0.6 -0.9 -0.8 -0.3
Heart disease (siblings) 0.4 0.5 3.5 -0.0 0.2 0.3 0.3 0.2 -0.5 0.6 -0.2 -0.5 0.2 0.3 1.0 -0.7 -1.9 0.3 -0.1 -0.1 0.6 -0.0 0.7 0.6 1.4 1.0 0.6
Alcohol drinker status: Previous 0.5 0.5 2.7 -0.6 -0.3 -0.5 -0.7 -0.3 -1.0 -0.9 -0.2 0.7 1.6 0.1 0.1 0.3 0.4 -0.9 -1.3 -0.9 -0.5 -0.1 -0.0 -0.6 -0.8 -0.9 -1.1
Pack years of smoking 1.8 2.6 5.1 1.3 1.8 1.8 1.7 1.0 1.4 1.1 1.7 -1.6 1.5 1.9 1.8 2.2 1.4 1.7 2.1 2.0 1.5 1.8 1.3 1.6 1.1 1.0 1.5
Impedance of whole body 0.8 4.0 10.9 -0.5 -2.1 -1.6 -2.0 -0.9 -1.9 -0.8 -1.5 2.4 -2.4 -2.5 -2.7 -1.4 -0.2 -2.6 -2.3 -2.1 -1.5 -2.2 -3.3 -2.0 -2.5 -2.1 -0.2
Leg fat mass (left) 0.1 0.3 1.6 0.6 0.3 0.4 0.5 -1.3 0.6 -0.1 0.6 -0.5 0.1 -0.2 -0.7 -0.3 0.2 0.6 1.1 1.1 -0.1 -0.2 0.3 0.2 0.3 0.4 0.8
Arm predicted mass (left) 0.3 1.3 11.1 -0.8 0.1 0.5 0.6 1.9 1.1 0.3 0.8 -0.6 -0.3 0.7 1.6 0.8 3.3 0.7 0.9 0.9 0.5 0.4 2.2 0.1 -1.1 -1.1 -0.2