Best TWAS P=1.69e-20 · Best GWAS P=3.89e-101 conditioned to 6.25e-68
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | TMEM161B-AS1 | 0.11 | 0.04 | lasso | 8 | 0.07 | 2.2e-03 | 3.0 | 8.6 | 6.2e-18 | 0.28 | 0.08 | 0.3 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 6.9 | 7.0 | 3.5e-12 | 0.24 | 0.99 | 0.0 | TRUE |
| 3 | YFS | Blood | MEF2C | 0.16 | 0.09 | enet | 28 | 0.12 | 5.1e-36 | -9.8 | 9.3 | 1.7e-20 | 0.14 | 1.00 | 0.0 | TRUE |