Best TWAS P=1.2e-11 · Best GWAS P=3.81e-13 conditioned to 0.00193
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | DNAJC18 | 0.17 | 0.01 | lasso | 10 | 0.04 | 2.0e-02 | -2.5 | -6.2 | 5.6e-10 | 0.79 | 0.03 | 0.82 | FALSE |
| 2 | GTEx | Esophagus Mucosa | TMEM173 | 0.10 | 0.03 | enet | 20 | 0.10 | 1.8e-07 | -6.9 | 5.5 | 4.9e-08 | -0.49 | 0.04 | 0.79 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | UBE2D2 | 0.05 | 0.02 | enet | 6 | 0.03 | 4.4e-04 | -5.5 | -6.8 | 1.2e-11 | 0.79 | 0.02 | 0.92 | TRUE |