TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Blood Platelet Count
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chr5:138,053,059-139,557,385
Best TWAS P=1.2e-11 · Best GWAS P=3.81e-13 conditioned to 0.00193
138M
138.2M
138.4M
138.6M
138.8M
139M
139.2M
139.4M
139.6M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
UBE2D2
0.05
0.02
enet
6
0.03
4.4e-04
-5.5
-6.8
1.2e-11
0.79
0.02
0.92
TRUE
1
GTEx
Esophagus Gastroesophageal Junction
DNAJC18
0.17
0.01
lasso
10
0.04
2.0e-02
-2.5
-6.2
5.6e-10
0.79
0.03
0.82
FALSE
2
GTEx
Esophagus Mucosa
TMEM173
0.10
0.03
enet
20
0.10
1.8e-07
-6.9
5.5
4.9e-08
-0.49
0.04
0.79
FALSE