Best TWAS P=5.67e-08 · Best GWAS P=2.01e-07 conditioned to 0.585
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | KIAA1467 | 0.45 | 0.21 | lasso | 6 | 0.23 | 1.1e-12 | 5.0 | 5.4 | 5.8e-08 | 0.97 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Nerve Tibial | KIAA1467 | 0.14 | 0.07 | enet | 14 | 0.06 | 2.3e-05 | 5.2 | 5.3 | 8.8e-08 | 0.93 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Testis | KIAA1467 | 0.25 | 0.11 | lasso | 9 | 0.08 | 2.4e-04 | 5.2 | 5.2 | 2.1e-07 | 0.98 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HEBP1 | 0.03 | 0.02 | lasso | 3 | 0.01 | 1.8e-03 | 5.2 | -5.4 | 5.7e-08 | -0.92 | 0.00 | 0.98 | TRUE |