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chr12:55,694,116-57,125,879

Best TWAS P=1.34e-08 · Best GWAS P=3.76e-08 conditioned to 0.179

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RPS26	0.48	0.62	lasso	5	0.63	5.9e-99	-5.3	-5.2	2.1e-07	0.88	0.00	0.99	FALSE
2	GTEx	Artery Tibial	SUOX	0.18	0.14	enet	23	0.18	2.1e-14	-4.7	5.4	5.9e-08	-0.85	0.04	0.96	FALSE
3	GTEx	Artery Tibial	RPS26	0.07	0.02	enet	5	0.01	3.5e-02	-5.3	-5.4	8.2e-08	0.93	0.01	0.97	FALSE
4	GTEx	Cells Transformed fibroblasts	RPS26	0.11	0.08	enet	15	0.09	3.4e-07	-5.1	-5.4	6.6e-08	0.85	0.02	0.98	FALSE
5	GTEx	Colon Transverse	SUOX	0.24	0.22	enet	24	0.25	3.8e-12	-4.6	5.2	1.7e-07	-0.77	0.02	0.98	FALSE
6	GTEx	Nerve Tibial	RPS26	0.12	0.09	enet	7	0.11	3.0e-08	-5.5	-5.5	3.6e-08	0.95	0.00	1.00	FALSE
7	GTEx	Ovary	RPS26	0.50	0.24	enet	25	0.22	5.0e-06	-5.0	-5.7	1.3e-08	0.84	0.01	0.98	TRUE
8	METSIM	Adipose	RPS26	0.30	0.40	lasso	5	0.41	7.2e-66	-5.1	-5.2	1.9e-07	0.90	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPS26	0.14	0.22	lasso	2	0.23	4.8e-19	-5.1	-5.2	1.9e-07	0.90	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPS26	0.30	0.44	enet	10	0.45	5.2e-104	-5.3	-5.2	1.5e-07	0.90	0.00	0.99	FALSE
11	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	RPS26	0.23	0.40	lasso	2	0.39	1.5e-20	-5.3	-5.2	2.4e-07	0.88	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Colon Adenocarcinoma	RPS26	0.43	0.48	lasso	4	0.47	1.8e-30	-5.3	-5.1	2.9e-07	0.88	0.00	0.99	FALSE
13	The Cancer Genome Atlas	Esophageal Carcinoma	RPS26	0.19	0.13	lasso	5	0.11	2.4e-04	-5.3	-5.2	2.2e-07	0.88	0.01	0.96	FALSE
14	The Cancer Genome Atlas	Glioblastoma Multiforme	RPS26	0.41	0.38	enet	9	0.39	7.9e-13	-5.1	-5.2	2.1e-07	0.91	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RPS26	0.17	0.29	lasso	4	0.29	6.2e-33	-5.1	-5.3	1.3e-07	0.91	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	RPS26	0.27	0.38	enet	8	0.40	5.0e-24	-5.3	-5.1	2.8e-07	0.90	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	RPS26	0.18	0.31	lasso	2	0.29	3.9e-14	-5.3	-5.3	1.5e-07	0.88	0.01	0.99	FALSE
18	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	RPS26	0.22	0.31	lasso	3	0.31	1.6e-35	-5.3	-5.2	2.2e-07	0.90	0.00	0.99	FALSE
19	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	RPS26	0.36	0.44	lasso	7	0.42	2.4e-19	-5.1	-5.2	1.6e-07	0.92	0.01	0.98	FALSE
20	The Cancer Genome Atlas	Rectum Adenocarcinoma	RPS26	0.24	0.18	lasso	2	0.20	1.9e-05	-5.3	-5.1	2.9e-07	0.88	0.01	0.92	FALSE
21	The Cancer Genome Atlas	Soft Tissue Sarcoma	RPS26	0.23	0.31	lasso	3	0.30	2.4e-18	-5.3	-5.2	1.9e-07	0.88	0.00	0.99	FALSE
22	The Cancer Genome Atlas	Stomach Adenocarcinoma	RPS26	0.19	0.32	lasso	5	0.34	2.0e-25	-5.1	-5.2	2.1e-07	0.89	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RPS26	0.46	0.64	lasso	4	0.65	8.5e-30	-5.3	-5.2	2.5e-07	0.89	0.01	0.99	FALSE