Best TWAS P=5.15e-09 · Best GWAS P=5.23e-08 conditioned to 0.8
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | KRT6C | 0.02 | 0.03 | lasso | 4 | 0.02 | 3.1e-05 | 4.9 | -5.4 | 8.2e-08 | -0.78 | 0.03 | 0.96 | FALSE |
| 2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | KRT6B | 0.06 | 0.02 | blup | 76 | 0.02 | 5.8e-02 | 5.1 | -5.7 | 1.4e-08 | -0.82 | 0.02 | 0.76 | FALSE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | KRT6B | 0.26 | 0.06 | blup | 79 | 0.11 | 1.7e-03 | 5.4 | -5.3 | 1.1e-07 | -0.53 | 0.02 | 0.41 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | KRT6B | 0.04 | 0.02 | blup | 78 | 0.03 | 5.2e-03 | -5.4 | -5.8 | 5.1e-09 | -0.91 | 0.02 | 0.83 | TRUE |