[Hub]/) : Traits : Hair Pigment :

chr13:94,398,894-95,983,387

Best TWAS P=1.02e-118 · Best GWAS P=1.55e-129 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DCT 0.17 0.15 lasso 6 0.15 1.1e-17 23.1 22.5 2.6e-112 0.87 1.00 0.00 FALSE
2 GTEx Cells Transformed fibroblasts GPR180 0.21 0.12 lasso 5 0.16 9.8e-12 5.2 5.8 8.3e-09 0.33 1.00 0.00 FALSE
3 GTEx Esophagus Mucosa GPR180 0.48 0.34 enet 23 0.42 6.1e-30 -3.6 6.0 2.0e-09 0.34 1.00 0.00 TRUE
4 GTEx Lung GPR180 0.40 0.31 enet 64 0.33 2.6e-26 -3.6 5.8 5.3e-09 0.37 1.00 0.00 FALSE
5 METSIM Adipose DCT 0.17 0.15 enet 43 0.17 3.2e-24 23.1 22.1 2.6e-108 0.81 0.04 0.96 TRUE
6 YFS Blood GPR180 0.28 0.26 lasso 3 0.31 1.3e-102 7.4 5.9 4.0e-09 0.33 1.00 0.00 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma GPR180 0.14 0.06 blup 63 0.08 5.9e-16 -3.6 6.1 1.1e-09 0.32 1.00 0.00 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma GPR180 0.11 0.07 blup 63 0.07 9.8e-05 -3.6 5.5 3.4e-08 0.33 0.53 0.07 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GPR180 0.12 0.06 blup 63 0.06 5.3e-07 -3.7 6.5 6.6e-11 0.26 0.99 0.00 TRUE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma GPR180 0.09 0.06 enet 7 0.07 5.0e-04 5.7 5.6 2.1e-08 0.27 0.07 0.04 TRUE
11 The Cancer Genome Atlas Lung Adenocarcinoma GPR180 0.13 0.03 blup 63 0.06 4.0e-07 -3.9 10.6 3.8e-26 0.48 0.95 0.03 TRUE
12 The Cancer Genome Atlas Lung Adenocarcinoma TGDS 0.04 0.02 blup 52 0.03 2.9e-04 -3.6 5.8 5.9e-09 0.12 0.25 0.05 TRUE
13 The Cancer Genome Atlas Thyroid Carcinoma DCT 0.08 0.07 lasso 3 0.06 1.4e-06 23.1 23.2 1.0e-118 0.88 0.05 0.95 TRUE