Best TWAS P=1.77e-164 · Best GWAS P=0 conditioned to 3.4e-146
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RNF219 | 0.08 | 0.02 | enet | 16 | 0.02 | 7.2e-03 | 1.1 | -5.8 | 8.0e-09 | 0.03 | 0.26 | 0.03 | TRUE |
| 2 | METSIM | Adipose | EDNRB | 0.05 | 0.03 | bslmm | 465 | 0.04 | 3.1e-06 | -21.4 | 26.7 | 1.8e-157 | -0.69 | 0.05 | 0.95 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EDNRB | 0.02 | 0.00 | blup | 60 | 0.00 | 3.1e-02 | -30.5 | 27.3 | 1.8e-164 | -0.46 | 0.01 | 0.19 | TRUE |