[Hub]/) : Traits : Hair Pigment :

chr14:70,676,661-72,273,020

Best TWAS P=6.77e-12 · Best GWAS P=2.67e-12 conditioned to 0.118

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PCNX 0.17 0.21 lasso 3 0.22 1.9e-17 -4.5 5.5 4.8e-08 -0.74 0.26 0.74 FALSE
2 GTEx Adipose Visceral Omentum PCNX 0.09 0.04 lasso 2 0.03 9.9e-03 -6.8 6.8 8.2e-12 -0.85 0.03 0.91 FALSE
3 GTEx Artery Aorta PCNX 0.26 0.32 enet 32 0.29 3.7e-16 -4.5 5.5 4.4e-08 -0.72 0.55 0.45 FALSE
4 GTEx Artery Tibial PCNX 0.21 0.32 lasso 5 0.31 6.7e-25 -4.5 5.2 2.6e-07 -0.75 0.91 0.09 FALSE
5 GTEx Brain Putamen basal ganglia PCNX 0.22 0.12 lasso 7 0.13 6.8e-04 -6.8 6.3 2.1e-10 -0.86 0.02 0.92 FALSE
6 GTEx Breast Mammary Tissue (Male) PCNX 0.11 0.11 lasso 3 0.07 1.3e-02 -6.5 6.4 1.6e-10 -0.80 0.04 0.54 FALSE
7 GTEx Cells Transformed fibroblasts PCNX 0.14 0.06 enet 28 0.10 1.2e-07 -4.7 5.7 1.4e-08 -0.65 0.09 0.91 FALSE
8 GTEx Esophagus Mucosa PCNX 0.20 0.18 enet 18 0.20 2.4e-13 -6.5 6.4 1.8e-10 -0.82 0.03 0.97 FALSE
9 GTEx Pituitary PCNX 0.39 0.35 lasso 3 0.34 2.6e-09 -6.5 6.3 2.6e-10 -0.88 0.02 0.98 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic PCNX 0.18 0.18 lasso 4 0.19 1.7e-10 -4.5 5.9 3.2e-09 -0.79 0.04 0.96 FALSE
11 GTEx Skin Sun Exposed Lower leg PCNX 0.23 0.29 enet 30 0.29 2.1e-24 -4.5 5.6 2.8e-08 -0.73 0.82 0.18 FALSE
12 GTEx Testis PCNX 0.14 0.09 enet 12 0.07 3.2e-04 -4.7 5.7 1.3e-08 -0.77 0.04 0.94 FALSE
13 GTEx Thyroid PCNX 0.27 0.29 enet 36 0.27 4.8e-21 -4.5 5.9 3.8e-09 -0.74 0.92 0.08 FALSE
14 METSIM Adipose PCNX 0.13 0.11 blup 440 0.11 2.5e-16 -4.8 5.4 8.3e-08 -0.69 0.83 0.17 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma PCNX 0.05 0.04 blup 92 0.04 4.2e-09 -6.8 5.3 1.3e-07 -0.70 0.02 0.98 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PCNX 0.08 0.01 blup 91 0.02 6.2e-03 -6.9 5.9 4.4e-09 -0.87 0.02 0.94 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma PCNX 0.03 0.02 blup 92 0.03 4.9e-04 -6.9 6.7 1.8e-11 -0.90 0.02 0.98 FALSE
18 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PCNX 0.04 0.04 lasso 4 0.03 2.4e-04 -6.5 6.9 6.8e-12 -0.95 0.01 0.98 TRUE
19 The Cancer Genome Atlas Prostate Adenocarcinoma PCNX 0.06 0.06 blup 91 0.07 7.1e-08 -4.6 5.3 1.2e-07 -0.66 0.13 0.87 FALSE
20 The Cancer Genome Atlas Testicular Germ Cell Tumors PCNX 0.17 0.09 blup 92 0.11 1.5e-04 -6.5 6.5 8.5e-11 -0.81 0.01 0.87 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma PCNX 0.08 0.06 blup 91 0.08 8.8e-08 -6.9 5.9 3.1e-09 -0.71 0.04 0.96 FALSE