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chr14:91,553,016-93,994,870

Best TWAS P=2.47e-252 · Best GWAS P=0 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LGMN	0.11	0.04	bslmm	565	0.05	1.1e-06	3.45	-8.0	1.9e-15	-0.11	0.96	0.00	TRUE
2	GTEx	Adipose Subcutaneous	ATXN3	0.19	0.17	lasso	5	0.17	1.7e-13	-5.11	-5.2	2.4e-07	0.01	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	ATXN3	0.19	0.14	lasso	6	0.12	7.0e-07	-4.91	-5.8	4.9e-09	0.00	1.00	0.00	FALSE
4	GTEx	Adrenal Gland	RP11-529H20.5	0.10	0.10	enet	13	0.08	1.1e-03	-0.84	6.3	3.3e-10	0.08	0.40	0.03	FALSE
5	GTEx	Brain Cerebellar Hemisphere	RIN3	0.61	0.00	enet	46	0.06	1.6e-02	11.40	5.2	1.9e-07	0.04	0.06	0.05	FALSE
6	GTEx	Brain Cerebellum	ATXN3	0.26	-0.01	enet	70	0.02	6.3e-02	8.08	14.2	1.2e-45	0.11	0.09	0.12	FALSE
7	GTEx	Brain Hippocampus	ATXN3	0.28	0.03	lasso	16	0.12	8.9e-04	-10.90	-8.1	4.4e-16	-0.04	0.19	0.04	FALSE
8	GTEx	Brain Hypothalamus	TC2N	0.25	0.33	lasso	4	0.36	3.3e-09	2.63	5.2	1.5e-07	0.11	0.54	0.04	TRUE
9	GTEx	Cells Transformed fibroblasts	ATXN3	0.14	0.10	lasso	9	0.09	6.0e-07	-5.11	-5.3	1.3e-07	0.01	1.00	0.00	FALSE
10	GTEx	Cells Transformed fibroblasts	RIN3	0.27	0.14	enet	27	0.12	2.8e-09	0.36	10.5	1.4e-25	-0.06	1.00	0.00	FALSE
11	GTEx	Cells Transformed fibroblasts	TRIP11	0.09	0.04	lasso	2	0.00	3.8e-01	-4.89	-5.7	9.9e-09	0.02	0.23	0.06	FALSE
12	GTEx	Colon Sigmoid	TRIP11	0.15	0.09	enet	18	0.07	1.7e-03	8.08	9.4	4.8e-21	0.15	0.18	0.16	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	ATXN3	0.32	0.17	enet	41	0.18	6.1e-07	-5.11	14.8	1.7e-49	0.15	0.95	0.02	TRUE
14	GTEx	Esophagus Gastroesophageal Junction	RP11-529H20.5	0.17	0.02	enet	23	0.01	9.6e-02	-4.98	33.9	2.5e-252	0.38	0.18	0.49	TRUE
15	GTEx	Esophagus Mucosa	TRIP11	0.09	0.01	lasso	4	0.00	2.4e-01	-1.22	-7.7	1.7e-14	-0.08	0.16	0.03	TRUE
16	GTEx	Heart Atrial Appendage	ATXN3	0.13	0.04	enet	7	0.07	5.0e-04	-12.78	9.9	4.8e-23	-0.01	0.27	0.04	TRUE
17	GTEx	Nerve Tibial	TRIP11	0.21	0.14	lasso	6	0.11	3.7e-08	-5.11	-5.7	1.1e-08	0.00	1.00	0.00	FALSE
18	GTEx	Ovary	TRIP11	0.29	-0.01	enet	24	0.03	6.7e-02	-3.99	6.8	7.8e-12	0.06	0.12	0.08	TRUE
19	GTEx	Prostate	TRIP11	0.42	-0.01	enet	79	0.05	1.8e-02	-0.37	-30.4	2.0e-203	-0.32	0.07	0.24	TRUE
20	GTEx	Small Intestine Terminal Ileum	RP11-529H20.6	0.36	0.32	lasso	8	0.26	1.8e-06	-4.88	-6.7	2.4e-11	-0.01	0.82	0.01	TRUE
21	GTEx	Stomach	RP11-529H20.5	0.19	0.12	enet	32	0.12	2.2e-06	-4.97	7.7	1.4e-14	0.06	0.94	0.00	TRUE
22	GTEx	Testis	RP11-529H20.6	0.23	0.23	lasso	3	0.22	4.9e-10	-4.97	-5.1	3.0e-07	0.01	1.00	0.00	FALSE
23	METSIM	Adipose	GOLGA5	0.07	0.03	blup	539	0.02	1.1e-04	-1.17	20.6	7.3e-94	0.33	0.60	0.10	TRUE
24	METSIM	Adipose	SLC24A4	0.18	0.08	bslmm	652	0.12	3.7e-17	-4.45	11.2	3.9e-29	0.10	1.00	0.00	TRUE
25	METSIM	Adipose	TRIP11	0.05	0.04	enet	13	0.02	3.8e-04	-0.39	-6.7	1.6e-11	0.00	0.98	0.00	TRUE
26	NTR	Blood	SLC24A4	0.13	0.05	enet	34	0.10	4.8e-32	-2.25	17.1	1.2e-65	0.12	1.00	0.00	TRUE
27	YFS	Blood	FBLN5	0.79	0.51	enet	134	0.68	1.1e-315	2.96	-7.6	2.1e-14	-0.03	1.00	0.00	TRUE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	SLC24A4	0.06	0.06	blup	162	0.05	4.6e-11	-5.03	11.5	1.9e-30	0.08	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC24A4	0.23	0.12	blup	160	0.20	6.0e-12	-5.19	11.0	4.0e-28	0.02	0.96	0.00	TRUE