Best TWAS P=1.22e-08 · Best GWAS P=9.46e-09 conditioned to 0.313
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | EMP2 | 0.22 | 0.16 | enet | 24 | 0.20 | 3.6e-24 | -5.2 | 5.5 | 3.2e-08 | -0.71 | 0.04 | 0.96 | TRUE |
| 2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | TEKT5 | 0.14 | 0.05 | lasso | 4 | 0.09 | 2.2e-09 | 4.1 | -5.7 | 1.2e-08 | 0.47 | 0.36 | 0.62 | TRUE |
| 3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TEKT5 | 0.17 | 0.01 | enet | 5 | 0.07 | 2.3e-03 | 4.1 | -5.6 | 2.6e-08 | 0.56 | 0.02 | 0.53 | FALSE |