Best TWAS P=2.19e-12 · Best GWAS P=6.65e-46 conditioned to 3.62e-40
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hippocampus | SGMS2 | 0.36 | -0.01 | enet | 37 | 0.04 | 4.0e-02 | -1.3 | -7.0 | 2.2e-12 | 0.28 | 0.04 | 0.16 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | LOC285456 | 0.10 | 0.08 | lasso | 6 | 0.06 | 4.9e-03 | -5.6 | 5.6 | 1.8e-08 | 0.08 | 0.06 | 0.06 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LOC285456 | 0.06 | 0.07 | lasso | 3 | 0.06 | 3.8e-07 | -5.6 | 5.4 | 6.2e-08 | 0.09 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HADH | 0.04 | 0.00 | blup | 55 | 0.00 | 1.2e-01 | 4.4 | 5.8 | 6.1e-09 | 0.01 | 0.02 | 0.15 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | LOC285456 | 0.08 | 0.04 | blup | 57 | 0.04 | 2.6e-05 | -5.1 | 5.7 | 1.0e-08 | 0.07 | 0.55 | 0.17 | TRUE |
| 6 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LOC285456 | 0.06 | 0.01 | lasso | 3 | 0.03 | 2.7e-03 | -5.6 | 5.3 | 1.2e-07 | 0.06 | 0.11 | 0.08 | FALSE |