Best TWAS P=5.7e-09 · Best GWAS P=1.97e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | LRP2BP | 0.07 | 0.05 | lasso | 7 | 0.05 | 1.1e-16 | 5.8 | 5.8 | 8.1e-09 | 0.96 | 0.01 | 0.99 | FALSE |
| 2 | NTR | Blood | SNX25 | 0.05 | 0.03 | lasso | 8 | 0.03 | 7.2e-10 | 6.0 | 5.8 | 6.1e-09 | 0.98 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | KIAA1430 | 0.03 | 0.04 | lasso | 2 | 0.03 | 1.2e-04 | 5.8 | 5.8 | 5.7e-09 | 0.99 | 0.00 | 1.00 | TRUE |