Best TWAS P=4.64e-47 · Best GWAS P=3.11e-102 conditioned to 1.74e-36
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NDUFS4 | 0.13 | 0.03 | bslmm | 474 | 0.10 | 3.3e-12 | 5.3 | 12.7 | 7.5e-37 | 0.44 | 0.23 | 0.77 | TRUE |
| 2 | GTEx | Artery Tibial | NDUFS4 | 0.09 | 0.01 | enet | 16 | 0.04 | 4.3e-04 | -7.4 | 10.6 | 3.2e-26 | 0.45 | 0.18 | 0.10 | FALSE |
| 3 | GTEx | Muscle Skeletal | NDUFS4 | 0.07 | 0.05 | lasso | 2 | 0.04 | 1.2e-04 | 9.4 | -9.0 | 2.6e-19 | -0.20 | 0.43 | 0.02 | FALSE |
| 4 | YFS | Blood | NDUFS4 | 0.12 | 0.09 | enet | 30 | 0.13 | 1.3e-40 | -10.6 | -9.5 | 1.6e-21 | -0.16 | 1.00 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NDUFS4 | 0.05 | 0.02 | enet | 8 | 0.03 | 1.4e-04 | 15.7 | 14.4 | 4.6e-47 | 0.60 | 0.30 | 0.03 | TRUE |