TWAS hub - NDUFS4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1320	0.0350	8.3e-08	0.030	0.088	0.069	0.100	0.075	1.3e-04	7.9e-11	7.7e-09	3.2e-12	1.9e-09
2	GTEx	Artery Tibial	0.0897	0.0368	5.0e-03	0.013	NA	0.040	NA	0.021	3.0e-02	NA	4.3e-04	NA	8.0e-03
3	GTEx	Brain Cerebellum	0.2740	0.0990	7.7e-03	0.003	NA	-0.002	NA	-0.008	2.6e-01	NA	3.7e-01	NA	6.7e-01
4	GTEx	Muscle Skeletal	0.0690	0.0291	6.9e-03	0.050	NA	0.033	NA	0.038	1.1e-05	NA	3.4e-04	NA	1.2e-04
5	GTEx	Nerve Tibial	0.1206	0.0407	1.4e-03	0.002	NA	0.000	NA	0.003	2.3e-01	NA	3.0e-01	NA	1.9e-01
6	GTEx	Skin Sun Exposed Lower leg	0.1320	0.0370	7.0e-05	0.042	NA	0.054	NA	0.050	1.9e-04	NA	2.9e-05	NA	5.7e-05
7	GTEx	Thyroid	0.1190	0.0460	3.6e-03	0.022	NA	-0.003	NA	0.022	7.9e-03	NA	7.4e-01	NA	8.0e-03
8	METSIM	Adipose	0.0692	0.0231	2.0e-04	0.027	0.022	0.049	0.030	0.054	6.2e-05	2.6e-04	7.4e-08	1.9e-05	1.5e-08
9	YFS	Blood	0.1181	0.0206	0.0e+00	0.092	0.100	0.131	0.042	0.073	1.2e-28	5.9e-31	1.3e-40	1.6e-13	9.1e-23
10	TCGA	Prostate Adenocarcinoma	0.0453	0.0219	3.7e-04	0.020	0.034	0.035	NA	0.029	3.1e-03	1.5e-04	1.4e-04	NA	4.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Impedance of arm (right)	4.4	20.3	62.6	5.5	5.0	1.9	-5.5	3.9	2.9	-1.8	2.3	-4.4	7.9
Handedness (chirality/laterality): Left-handed	4.3	5.1	13.4	1.9	0.9	-0.4	1.6	3.4	2.9	1.3	3.7	2.0	2.4
Medication: Amlodipine	3.8	5.4	17.0	-1.5	-0.5	0.9	-4.1	-1.4	-2.4	-3.3	-1.8	-3.0	1.7
Impedance of arm (left)	3.4	15.5	49.4	4.5	3.8	1.5	-5.0	3.6	1.9	-2.3	1.9	-4.2	7.0
Mouth/teeth dental problems: Dentures	3.3	5.5	12.0	-3.5	-1.8	-0.0	0.9	-1.1	-2.2	-2.9	-3.1	-2.5	-2.9
Ever had bowel cancer screening	3.0	3.6	6.7	-1.1	-1.0	0.0	-0.1	-2.5	-2.2	-2.2	-2.6	-2.4	-2.3
Eye problems/disorders: Cataract	3.0	3.5	9.1	1.9	1.4	0.9	0.7	2.2	2.1	1.9	3.0	1.7	1.8
Impedance of whole body	2.6	13.2	36.0	2.4	2.4	-0.7	-5.1	2.8	0.8	-4.3	0.1	-6.0	5.5
Hair Pigment	2.5	71.6	207.4	12.7	10.6	-1.5	-9.0	2.9	3.7	-4.9	3.9	-9.5	14.4
Impedance of leg (left)	2.5	12.1	49.3	-0.8	0.2	-2.1	-4.3	1.0	-0.8	-5.9	-2.3	-7.0	2.6
Breastfed as a baby	2.5	3.1	8.1	1.5	-0.5	2.8	0.4	1.4	2.2	0.7	2.4	2.1	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.5	3.0	7.6	-2.8	-2.7	-1.0	1.2	-1.5	-1.5	-0.0	-1.3	0.7	-2.4
Illnesses of father: Heart disease	2.5	3.5	9.0	-0.6	-0.3	-0.7	-3.0	-1.8	-2.0	-2.7	-1.8	-2.5	1.1
Medication: Simvastatin	2.4	3.5	8.9	-3.0	-1.0	-1.9	-0.9	-0.6	-2.5	-2.4	-1.8	-2.1	-0.5
Falls in the last year	2.4	3.2	7.9	2.1	2.8	0.6	-1.4	1.6	2.3	0.4	1.6	0.1	2.7
Medication: Ventolin 100micrograms inhaler	2.4	3.0	8.4	2.3	2.9	-0.1	-1.4	1.6	1.8	1.0	1.3	0.1	2.5
Medication: Blood pressure	2.4	4.2	9.3	-2.2	1.6	-3.0	-2.0	-0.8	-1.5	-2.3	-2.1	-2.9	0.5
Ever smoked	2.4	4.3	13.8	1.7	1.4	0.6	1.9	0.9	1.6	3.7	2.5	3.3	-0.0
Coronary Artery Disease (CAD)	2.3	2.7	9.5	1.1	0.6	-1.2	-0.9	2.7	1.4	-1.2	1.5	-1.0	3.1
Hair/balding pattern: Pattern 2	2.3	2.9	10.6	3.2	1.2	1.1	-2.4	-0.2	0.7	-0.2	0.8	-1.5	2.5
Exposure to tobacco smoke outside home	2.3	3.1	8.7	-0.2	-0.4	0.5	-2.9	-2.6	-2.3	-1.6	-1.9	-1.7	-0.5
Pain type(s) experienced in last month: Hip pain	2.3	2.8	6.7	0.9	-1.0	2.6	1.8	-0.4	0.6	2.5	0.9	2.5	-1.6
Myopia	2.3	3.4	9.2	1.4	0.0	0.4	0.8	2.1	1.9	2.1	3.0	2.7	1.3
Medication: Lansoprazole	2.2	2.5	7.3	-1.9	-2.7	1.2	2.2	-0.6	-1.2	-0.5	-0.6	0.4	-2.4
Seen a psychiatrist for nerves, anxiety, tension or depression	2.2	2.9	7.5	1.0	2.7	-1.3	1.0	1.7	2.7	1.7	1.7	1.2	0.6
Triglycerides	2.1	3.5	12.0	-0.4	1.6	-2.6	-1.5	0.4	-0.5	-2.7	-1.0	-3.5	1.5
Diabetes (mother)	2.1	2.7	6.2	-1.9	-0.1	-0.7	-1.5	-1.8	-1.9	-1.8	-2.5	-2.0	-0.6
Primary Biliary Cirrhosis	2.0	2.8	9.4	3.1	0.7	1.4	-0.2	0.4	1.5	2.3	2.0	1.5	1.6
Loud music exposure frequency	2.0	2.2	6.0	1.7	1.3	0.7	0.4	0.9	1.2	2.5	1.8	1.8	1.4
Age at First Birth	1.9	2.7	11.0	3.3	1.2	1.8	-1.1	0.1	1.5	1.0	1.7	0.4	2.0
Medication: Co-codamol	1.9	2.2	6.6	1.1	2.6	-0.8	1.1	1.6	1.6	1.9	1.4	1.2	0.5
Impedance of leg (right)	1.9	9.3	37.7	0.2	0.4	-1.9	-4.0	1.4	-0.4	-4.8	-1.6	-6.1	2.7
Ever taken oral contraceptive pill	1.9	2.1	6.1	1.9	1.1	0.4	-0.2	0.3	1.6	2.5	1.5	2.1	0.3
Medication: Metformin	1.8	2.5	7.3	-1.5	2.0	-2.7	0.1	0.4	-1.3	-1.7	-1.4	-2.1	-0.5
Hand grip strength (right)	1.8	4.9	13.6	-1.7	-3.7	0.5	2.5	-2.2	-0.9	0.9	-0.1	3.3	-2.9
Hearing difficulty/problems with background noise	1.8	2.8	5.9	1.8	2.4	0.3	-0.0	2.0	2.1	1.1	2.2	0.7	2.0
Wheeze or whistling in the chest in last year	1.8	3.2	7.1	2.7	1.6	1.2	0.9	1.0	1.4	2.6	2.3	2.1	1.0
Osteoarthritis (self-reported)	1.8	2.3	5.6	-2.4	-0.4	-1.1	0.2	-2.0	-1.2	-0.9	-2.3	-0.6	-2.1
Medication: Lisinopril	1.8	2.4	5.3	-0.9	1.2	-0.6	-2.3	-2.0	-1.2	-1.0	-2.0	-2.3	0.3
Eye problems/disorders: Diabetes related eye disease	1.7	1.9	4.0	-1.8	0.7	-0.6	-0.1	-1.5	-1.7	-0.8	-2.0	-1.2	-1.9
Diabetes (self-reported)	1.7	2.6	7.7	-0.4	2.8	-1.3	-1.6	0.4	-0.6	-2.0	-1.0	-2.7	1.0
Time employed in main current job	1.7	2.0	5.7	-1.4	-0.2	-2.3	1.9	2.4	0.7	-1.1	0.2	-1.0	0.0
Pulse wave reflection index	1.7	2.2	6.6	-1.3	-0.3	0.3	-1.1	-2.1	-2.6	-0.4	-2.1	-1.4	-0.8
Medication: Seretide 50 evohaler	1.7	2.0	5.6	1.0	0.6	-0.8	-0.2	2.3	1.7	0.0	2.0	0.3	2.4
Crohns Disease (2012)	1.6	2.6	7.5	-1.1	-0.3	-1.5	-1.2	-1.6	-1.4	-2.7	-2.0	-2.1	-0.2
Hand grip strength (left)	1.6	4.3	9.7	-1.8	-2.6	-0.7	2.8	-1.9	-0.7	1.1	-0.3	3.1	-3.1
Trunk fat percentage	1.6	6.5	21.1	3.0	1.2	1.2	-2.1	3.9	1.9	0.1	3.0	-0.8	4.6
Age when periods started (menarche)	1.6	3.8	11.4	-0.8	-2.8	0.6	1.9	-2.1	-0.9	1.3	-0.4	2.7	-3.4
Number of incorrect matches in round	1.6	2.7	6.6	-2.0	-0.3	-0.6	-2.6	-1.4	-1.5	-2.0	-1.7	-2.1	0.6
Qualifications: None of the above	1.6	3.4	11.6	-3.4	0.1	-2.9	0.7	0.8	-0.3	-1.9	-1.9	-1.6	-1.8
Chronic bronchitis/emphysema (mother)	1.6	1.8	4.1	-2.0	-0.7	1.0	0.1	-1.4	-1.3	-0.6	-2.0	-0.7	-2.0
Age at last live birth	1.6	2.3	8.8	2.4	0.1	0.2	-2.2	0.4	0.2	-0.9	1.3	-1.0	3.0
Leg pain on walking	1.6	2.0	5.2	-2.3	-0.7	-1.9	1.2	-0.7	-0.9	-1.2	-1.6	-0.6	-1.9
Long-standing illness, disability or infirmity	1.6	2.4	10.3	-3.2	-0.5	-2.2	1.3	0.7	-0.4	-1.6	-0.9	-0.6	-1.6
Medication: Gliclazide	1.6	1.8	5.3	-1.0	2.3	-1.1	-1.0	-1.2	-1.0	-1.0	-1.6	-1.9	-0.4
Medication: Bendroflumethiazide	1.6	2.5	8.2	-0.8	1.8	-1.6	-0.1	2.9	2.0	-0.5	1.0	-0.6	2.3
Illnesses of father: High blood pressure	1.6	2.0	5.9	0.2	0.7	-0.3	-2.4	-0.3	-1.0	-2.1	-0.8	-2.1	1.8
Taking other prescription medications	1.5	2.3	6.2	-2.5	0.8	-2.3	2.3	1.1	0.1	-0.7	-0.8	-0.3	-1.8
Noisy workplace	1.5	1.8	5.3	0.2	-0.9	0.5	0.7	-1.8	-1.1	1.8	-0.3	2.0	-2.3
Health satisfaction	1.5	1.9	5.1	-2.3	-1.4	-1.5	2.2	-0.2	-0.5	-0.8	-0.8	0.3	-1.8
High cholesterol (Self-reported)	1.5	2.6	8.5	-2.9	-1.4	-0.3	-1.3	-1.3	-1.9	-2.0	-1.7	-1.3	-0.4
Schizophrenia vs Biploar Disorder	1.4	1.9	5.9	-2.4	-0.3	0.1	2.2	-0.2	-0.1	0.4	-1.2	1.1	-2.3
Crohns Disease (2017)	1.4	3.1	7.1	-1.8	-1.2	-0.9	-0.9	-2.3	-1.8	-2.2	-2.7	-1.5	-1.5
Systolic Blood Pressure	1.4	7.1	35.1	1.1	3.5	-0.1	-5.9	0.1	0.4	-1.0	0.3	-2.1	4.1
Frequency of depressed mood in last 2 weeks	1.4	1.9	4.7	-0.9	-1.1	-0.8	-1.1	-2.2	-1.9	-1.2	-1.8	-1.2	-1.1
Arm fat percentage (right)	1.4	5.6	14.1	2.7	1.5	1.7	-1.1	3.7	2.0	1.2	3.0	0.2	3.8
Medication for cholesterol, blood pressure or diabetes	1.4	2.4	5.7	2.0	-1.0	2.4	1.6	0.7	1.4	1.6	1.2	1.8	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	5.4	1.3	-0.8	2.3	-1.4	-1.3	-0.0	1.0	1.0	1.7	0.6
Alcohol intake frequency.	1.4	3.3	10.3	-3.2	0.8	-3.1	0.9	1.1	-0.6	-1.1	-1.9	-1.4	-1.8
Illnesses of siblings: Diabetes	1.4	1.7	4.5	-0.5	0.1	2.1	-1.9	-1.0	-1.4	-0.9	-1.3	-1.9	0.2
Diabetes diagnosed by doctor	1.4	2.2	7.2	-0.9	2.0	-1.3	-1.2	0.0	-1.2	-2.0	-1.4	-2.7	0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.4	3.4	-0.8	0.2	-1.8	-1.8	-1.1	-0.6	-1.6	-1.1	-1.4	0.4
Wears glasses or contact lenses	1.4	1.6	3.5	0.9	1.3	-1.5	-0.2	1.9	1.6	0.2	1.5	0.1	1.6
Type 2 Diabetes (T2D) (2018)	1.3	2.5	8.0	-1.1	2.8	-1.1	-1.4	0.5	-0.9	-1.7	-1.3	-2.7	0.1
Overall health rating	1.3	2.7	9.1	-2.4	-1.8	-1.5	3.0	1.0	-0.5	-0.4	0.3	1.4	-1.8
Average weekly red wine intake	1.3	1.9	4.0	-0.8	-1.5	0.9	-1.5	-1.7	-1.4	-2.0	-1.6	-1.2	-0.3
Average weekly beer plus cider intake	1.3	1.8	5.5	1.4	2.4	-0.0	-0.6	0.7	1.9	1.7	1.0	0.7	1.5
Vascular/heart problems diagnosed by doctor	1.3	3.5	8.8	2.3	-1.1	1.4	3.0	0.5	1.9	2.0	1.6	2.3	-1.3
Ever used hormone-replacement therapy (HRT)	1.2	1.6	5.0	-0.5	2.2	-1.9	0.6	1.4	2.0	0.4	0.5	0.3	-0.0
Medication for hormone replacement therapy	1.2	1.4	4.9	1.2	2.2	0.3	-0.2	0.7	2.0	0.9	0.8	0.9	0.7
Sitting height	1.2	8.5	28.4	4.2	2.8	1.2	-2.7	1.6	3.6	-0.1	2.7	0.3	5.3
Pain all over the body in last month	1.2	1.3	3.6	-1.5	0.1	-1.9	-0.0	0.5	0.5	-1.7	-1.1	-1.6	-0.1
Hair/balding pattern: Pattern 3	1.2	1.7	3.8	-0.1	1.1	-0.7	0.9	1.7	1.3	1.4	1.8	1.9	1.1
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.8	1.8	0.5	0.9	-2.0	0.3	0.9	-0.7	0.7	-0.8	1.9
Prospective memory result	1.2	1.4	4.3	-2.1	0.7	-1.0	0.3	0.0	-0.0	-1.6	-1.7	-1.1	-1.4
Commuting to job workplace: Car/motor vehicle	1.2	1.3	8.2	-0.9	-2.9	0.7	0.3	-0.6	-0.6	-0.7	-0.6	0.2	-1.4
Back pain experienced in last month	1.2	1.8	9.1	-0.0	0.2	-1.1	3.0	1.9	1.1	0.3	0.5	0.8	-1.2
Guilty feelings	1.2	1.9	4.5	-1.6	-2.1	-1.4	2.1	-0.3	-0.2	0.1	-0.0	1.4	-1.9
Ever depressed for a whole week	1.2	1.5	8.3	-0.1	0.8	-2.9	1.6	1.4	0.4	0.3	0.7	0.6	-0.6
Body Mass Index (BMI) (2010)	1.1	1.4	4.1	1.6	2.0	0.4	0.5	1.2	1.6	1.1	1.0	-0.1	1.0
HDL Cholesterol	1.1	1.8	8.4	0.8	-1.9	2.9	-0.3	0.1	0.6	0.8	0.9	1.9	0.2
Lupus	1.1	1.6	3.7	0.0	-0.1	1.3	1.4	1.5	1.5	1.4	1.5	1.9	-0.3
Neuroticism (2016)	1.1	1.6	6.3	-0.6	-1.4	-0.9	1.9	-0.6	-0.7	0.7	-0.5	1.1	-2.5
Type 2 Diabetes (T2D) (2012)	1.1	1.3	5.7	1.7	2.4	-0.8	-1.3	-0.9	-0.4	0.5	-0.1	-1.0	0.2
Smoking Status	1.1	2.7	8.1	2.2	1.4	1.0	0.3	-0.3	1.6	2.8	1.6	2.4	-0.5
Allergy or Eczema	1.1	2.9	8.3	-0.9	0.0	-2.6	2.4	-1.3	-1.8	0.3	-1.2	0.9	-2.9
Other serious medical condition/disability diagnosed by doctor	1.1	1.5	4.5	-2.0	-0.8	-0.9	2.1	1.1	0.4	-0.8	0.1	0.5	-1.6
Relative age voice broke	1.1	1.7	4.3	0.8	0.2	1.3	1.4	0.4	2.1	1.9	0.9	2.0	-0.2
High blood pressure	1.1	3.1	6.2	-2.1	1.3	-2.0	-2.5	-0.2	-1.5	-2.0	-1.4	-2.2	1.3
High blood pressure (mother)	1.1	1.5	3.9	0.7	2.0	-1.4	-0.1	1.3	1.0	1.4	1.2	0.5	1.6
Trunk fat mass	1.1	4.6	14.2	2.6	1.0	1.3	-1.5	3.1	1.9	0.5	2.7	0.1	3.8
Number of live births	1.1	1.6	4.4	-1.7	-1.3	-1.1	2.0	-0.2	-0.9	0.2	-0.5	0.6	-2.1
Ever highly irritable/argumentative for 2 days	1.1	1.3	3.8	1.0	1.9	-0.4	-0.0	0.5	1.7	1.9	0.9	1.0	0.4
Mouth/teeth dental problems: Loose teeth	1.1	1.3	6.5	-0.4	1.8	-2.5	1.0	0.7	1.0	0.4	0.2	0.2	-0.5
Medication for pain relief, constipation, heartburn	1.1	1.9	6.1	0.0	-0.2	2.5	-1.8	-2.3	-1.6	-0.3	-1.3	-0.6	0.3
Knee pain experienced in last month	1.1	1.7	6.6	-0.7	-0.3	-1.9	2.6	0.2	-0.8	1.0	0.5	1.5	-1.5
Friendships satisfaction	1.1	1.3	4.3	0.6	0.4	-0.5	0.9	1.2	2.1	1.1	1.4	1.2	1.0
Worry (Nagel 2018)	1.0	2.1	7.5	-2.2	-1.2	-2.7	1.1	-0.8	-1.3	-0.5	-1.0	0.1	-1.6
LDL Cholesterol	1.0	1.6	4.5	-0.9	0.5	-0.5	-1.5	0.2	-0.7	-2.1	-1.1	-2.1	1.2
Leg fat-free mass (left)	1.0	5.1	20.4	1.9	0.0	1.9	1.5	-0.4	1.4	3.7	2.3	4.5	0.2
Maternal smoking around birth	1.0	1.5	4.1	1.3	-0.6	1.2	1.1	-0.4	0.6	2.0	1.0	2.0	-0.5
Chronic bronchitis/emphysema (father)	1.0	1.2	3.3	0.1	-1.7	1.8	-0.2	-1.5	-1.1	0.5	-0.4	0.6	-1.3
Had menopause	1.0	1.3	3.3	0.3	0.7	-0.2	1.8	1.6	1.7	1.2	1.0	1.0	-0.3
Depression (self-reported)	1.0	1.2	4.3	-1.3	1.0	-2.1	1.1	0.1	-0.1	-0.7	-1.0	-1.2	-1.1
Pulse wave Arterial Stiffness index	1.0	1.2	4.6	1.0	-0.0	2.2	-1.2	-1.6	-0.9	0.8	-0.5	0.2	0.5
Length of working week for main job	1.0	1.1	3.6	1.9	1.3	-0.1	-1.4	0.4	0.9	0.6	1.2	0.2	1.0
High blood pressure (siblings)	1.0	1.4	4.2	-2.1	0.3	-1.9	0.3	0.3	-1.2	-0.7	-1.3	-1.0	-1.2
Body fat percentage	1.0	4.1	13.6	1.8	0.7	0.6	-1.9	3.4	1.2	-0.4	2.1	-1.2	3.7
Number of children fathered	1.0	1.1	3.9	-1.4	-2.0	-0.5	1.1	1.3	0.5	-0.9	0.5	0.1	1.0
Arm fat percentage (left)	1.0	4.2	11.6	2.2	0.8	1.7	-0.9	3.4	1.4	0.8	2.7	0.2	3.3
Illnesses of father: None of the above (group 1)	1.0	1.3	3.2	0.6	-0.7	0.8	1.8	0.8	1.1	1.4	1.1	1.5	-0.8
Age started oral contraceptive pill	1.0	1.2	3.1	1.0	-0.3	-0.5	-0.2	1.8	1.2	0.6	1.6	1.0	1.5
Diastolic blood pressure, automated reading	1.0	3.2	9.9	2.2	3.1	-0.5	-2.6	1.1	1.2	0.9	1.0	-0.5	2.5
Schizophrenia (2018)	0.9	1.9	4.7	-1.1	-0.5	0.5	-0.7	-1.9	-1.7	-1.4	-2.2	-1.1	-1.5
Average weekly spirits intake	0.9	1.2	4.7	-1.5	0.3	-1.6	1.3	2.2	0.5	-0.4	-0.0	0.1	-0.2
Ever had hysterectomy (womb removed)	0.9	1.0	3.8	0.5	0.5	-1.1	0.5	2.0	1.0	0.7	1.1	0.1	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.3	3.2	-0.3	-1.6	0.7	0.6	-1.8	-1.0	0.7	-0.4	1.0	-1.8
Stomach or abdominal pain in last month	0.9	1.2	3.5	0.5	-0.2	0.9	1.2	-0.7	0.3	1.4	0.1	1.8	-1.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.2	1.1	1.2	-1.3	0.4	1.3	1.5	0.0	1.1	-0.2	1.0
Leg predicted mass (left)	0.9	5.0	20.1	1.9	0.1	1.9	1.4	-0.4	1.3	3.6	2.3	4.5	0.3
Past tobacco smoking	0.9	1.7	7.2	-0.5	-0.4	-0.6	-0.9	0.7	-0.0	-2.7	-0.8	-2.3	1.4
Qualifications: A levels/AS levels or equivalent	0.9	2.0	6.4	2.1	0.3	1.1	0.1	0.6	0.9	0.6	2.1	1.4	2.5
Medication: Cholesterol lowering	0.9	1.4	3.1	-1.6	0.3	-1.2	-1.8	-1.0	-1.4	-1.2	-0.8	-1.1	0.7
Pulse wave peak to peak time	0.9	1.0	3.9	-0.8	0.0	-2.0	1.1	1.6	0.9	-0.8	0.6	-0.1	-0.4
Comparative height size at age 10	0.9	4.8	14.6	2.8	3.2	0.4	-2.5	1.3	1.7	-0.4	0.9	-1.8	3.8
Suffer from ‘nerves’	0.9	1.4	9.7	-0.9	0.5	-3.1	-0.3	-0.3	-0.1	-0.9	-0.8	-1.1	-0.6
Family relationship satisfaction	0.9	1.2	3.7	-0.2	0.5	-0.7	1.1	1.9	1.7	0.3	1.3	0.7	0.6
Leg fat-free mass (right)	0.9	4.8	19.9	1.6	0.1	1.9	1.4	-0.5	1.5	3.5	2.3	4.5	0.3
Leg predicted mass (right)	0.9	4.7	19.6	1.5	0.1	1.9	1.4	-0.6	1.4	3.4	2.2	4.4	0.3
Miserableness	0.9	1.6	4.0	-1.4	0.5	-2.0	-1.0	-0.8	-0.9	-1.3	-1.6	-1.7	-0.8
Cholesterol lowering medication	0.9	1.4	5.4	-2.3	-0.5	-0.9	-0.4	0.0	-1.1	-1.6	-1.2	-1.3	-0.4
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.7	-1.7	0.1	-1.4	-1.4	0.1	-0.9	-1.2	-0.5	-1.2	1.1
Neuroticism (Nagel 2018)	0.8	1.8	4.8	-2.2	-1.6	-2.2	1.2	-0.3	-0.8	-0.1	-0.7	0.4	-1.8
Breast Cancer	0.8	2.0	6.9	0.2	0.6	0.9	-0.8	1.8	0.4	-1.8	0.6	-2.0	2.6
Bipolar Disorder (2011)	0.8	0.8	2.9	-0.4	0.2	-0.4	-1.5	-1.7	-0.4	-0.5	-1.0	-0.8	-0.6
HbA1C	0.8	0.9	6.2	0.2	-0.1	0.6	2.5	0.6	-0.3	0.7	0.6	0.9	-0.5
Relative age of first facial hair	0.8	1.7	5.6	1.8	1.7	-0.1	-2.4	-1.1	1.0	-0.3	-0.5	-1.3	1.0
Systolic blood pressure, automated reading	0.8	2.4	10.0	0.3	2.6	0.4	-3.2	0.5	0.9	-0.4	0.1	-1.2	2.1
Heart attack	0.8	1.0	2.3	-1.5	0.1	-1.4	-1.4	0.0	-0.9	-1.0	-0.4	-1.0	1.0
Medication: Ramipril	0.8	1.1	3.1	-0.0	1.8	-1.3	-1.6	-0.3	-0.3	-0.6	-0.8	-1.3	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.3	1.5	0.5	-1.4	0.7	0.9	1.5	0.5	1.3	0.1	0.4
Age at first live birth	0.8	1.5	5.8	2.4	-0.1	1.3	-1.9	-0.2	0.3	0.2	0.7	-0.5	1.7
Neck or shoulder pain in last month	0.8	1.2	6.8	-1.0	-0.7	0.3	2.6	0.5	-0.6	0.4	0.1	1.1	-1.2
Medication: Ibuprofen	0.8	1.0	3.6	1.1	0.4	-1.9	0.7	1.0	1.1	0.2	1.3	-0.0	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	3.0	1.1	-1.1	1.7	-0.3	-0.2	0.5	1.1	0.7	1.4	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	3.8	-0.2	-0.2	-0.5	0.5	-0.9	-1.0	1.3	-0.5	1.1	-1.9
Illness, injury, bereavement, stress in last 2 years	0.8	0.9	2.4	-0.9	1.4	-1.6	1.1	-0.0	0.9	1.1	0.1	1.0	-0.5
Hypertension (Self-reported)	0.8	2.3	5.7	-1.5	1.2	-1.6	-2.4	-0.2	-1.5	-1.5	-1.1	-1.9	1.3
Smoking status: Previous	0.8	1.3	5.9	0.3	0.3	0.3	0.7	-0.3	-0.0	2.4	0.6	2.0	-1.1
Loneliness, isolation	0.8	1.1	2.7	-1.1	-1.6	0.6	1.6	-0.5	-0.3	0.4	-0.4	1.0	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	6.8	-1.1	0.7	-2.6	1.4	-0.0	-0.2	0.4	-0.4	0.1	-1.6
Commuting to job workplace: Public transport	0.8	1.0	6.3	1.0	0.3	-0.0	-0.8	0.4	0.3	-0.7	1.2	-0.2	2.5
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	3.1	-1.3	-0.9	-1.7	1.8	0.6	0.3	0.2	0.3	0.5	-1.0
Depression (Nagel 2018)	0.7	1.0	3.9	-0.5	-1.0	0.6	-0.4	-2.0	-1.6	-0.3	-1.0	-0.4	-0.8
Rheumatoid Arthritis	0.7	1.0	2.8	0.7	-0.1	-0.3	0.6	1.4	1.4	-0.1	1.7	0.7	1.4
Cardiovascular Disease	0.7	2.3	5.1	-1.2	1.6	-1.3	-2.3	0.0	-1.7	-1.3	-1.1	-2.0	1.5
Current tobacco smoking	0.7	1.1	2.4	1.5	0.6	1.0	0.9	-0.5	1.0	1.5	0.9	1.4	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	4.7	2.2	1.6	1.2	-0.4	0.7	1.9	0.5	1.1	0.1	1.5
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	2.1	0.6	0.0	1.4	0.1	0.0	0.9	1.2	1.2	1.0	0.5
Alcohol usually taken with meals	0.7	1.1	7.1	-1.2	-2.7	-0.0	0.2	-0.8	-0.8	-0.5	-0.5	0.5	-0.6
Financial difficulties in last 2 years	0.7	0.9	3.2	-0.8	-1.3	-0.3	0.3	-0.9	-1.8	-0.3	-1.0	-0.0	-1.1
Mouth/teeth dental problems	0.7	1.0	2.7	1.3	0.0	1.4	-1.6	-0.9	-0.0	1.0	0.6	0.5	1.2
Worrier / anxious feelings	0.7	1.3	2.6	-1.2	-0.7	-1.6	-0.1	-1.3	-1.6	-0.6	-1.2	-0.8	-1.2
Arm fat mass (right)	0.7	2.8	5.9	2.0	0.5	1.5	-0.2	2.2	1.4	1.8	2.4	1.5	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.5	-0.8	-0.3	-1.9	1.7	0.2	0.1	0.4	-0.0	0.8	-1.6
Birth weight	0.7	1.6	4.2	0.5	-1.1	1.5	1.8	-0.2	-0.2	1.6	0.6	2.0	-1.2
Comparative body size at age 10	0.7	1.9	6.2	-1.0	-1.5	0.5	-0.4	-2.5	-1.7	-0.4	-1.4	0.7	-1.9
Medication: Allopurinol	0.7	1.0	5.5	-0.8	0.1	0.1	2.4	-0.6	-0.3	0.2	-0.9	-0.3	-1.5
Medication: Omeprazole	0.7	0.9	3.2	-1.4	-0.8	-1.8	1.5	0.3	-0.1	-0.0	-0.1	0.1	-0.8
Arm predicted mass (right)	0.7	3.4	11.6	-1.5	-2.0	0.1	2.2	-1.7	0.0	1.5	0.1	3.4	-2.4
Medication: Aspirin	0.7	1.0	2.9	0.6	0.0	0.2	0.1	1.5	0.3	0.5	1.7	1.4	1.3
Qualifications: nursing, teaching	0.7	1.1	4.0	-0.7	-2.0	-0.4	0.5	-1.6	-1.4	-0.5	-0.5	0.1	-1.1
Asthma (self-reported)	0.7	1.4	2.4	1.5	0.8	1.5	-0.7	0.3	1.5	1.4	1.1	1.4	0.8
Medication: Aspirin	0.7	0.9	3.0	0.2	-0.1	-0.1	0.1	1.7	0.3	0.3	1.7	1.2	1.3
Average weekly champagne plus white wine intake	0.7	1.0	5.1	0.4	-0.7	0.1	-1.1	0.7	0.6	-0.4	1.3	0.2	2.3
Mother’s age at death	0.7	0.8	2.7	0.5	0.7	1.4	-0.6	0.6	0.8	0.5	1.1	0.4	1.6
Eye problems/disorders: Glaucoma	0.7	0.8	2.0	-1.3	-0.5	-0.8	-0.4	-0.9	-1.4	-0.9	-1.2	-0.8	-0.3
Irritability	0.7	1.2	3.2	1.8	1.6	-1.0	0.0	0.7	1.4	0.4	1.2	0.3	0.9
Risk taking	0.7	1.0	4.2	0.7	0.1	0.2	0.3	-0.9	0.6	1.6	0.7	2.0	-0.9
Deep venous thrombosis (DVT) (self-reported)	0.7	0.8	2.6	-1.4	-1.1	0.1	-0.2	-1.6	-0.4	-0.3	-0.9	0.0	-1.3
Alzheimer’s Disease (in father)	0.6	0.7	1.9	-1.2	-1.3	-0.5	1.4	-0.2	-0.4	0.1	-0.2	0.6	-0.8
Major Depression (MDD)	0.6	0.8	3.2	0.3	1.0	-1.0	-0.2	0.6	0.1	-1.2	-0.0	-1.8	0.9
Chronotype (morning person)	0.6	1.3	3.3	-1.8	-0.7	-1.0	-0.1	-0.6	-1.4	-1.5	-1.3	-1.0	-0.9
Sensitivity / hurt feelings	0.6	1.1	2.6	-1.3	-1.6	-0.3	0.8	-1.0	-0.9	-0.2	-1.2	0.2	-1.6
Angina	0.6	0.8	2.8	-0.8	0.2	-1.2	-1.7	-1.2	-0.5	-0.6	-0.6	-0.4	-0.0
Diabetes (father)	0.6	0.7	1.7	-0.3	1.3	-1.3	-0.6	0.5	-0.3	-0.7	-0.3	-1.2	1.1
Average weekly fortified wine intake	0.6	0.8	2.0	0.7	-0.2	1.4	0.6	0.6	-0.0	1.1	1.3	1.0	0.5
Qualifications: CSEs or equivalent	0.6	0.8	2.0	0.7	0.9	1.4	0.3	-1.2	0.2	1.4	-0.1	1.0	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.9	0.2	-1.4	0.6	0.7	-1.1	-1.1	0.9	-0.1	1.4	-1.3
Illnesses of siblings	0.6	0.9	3.0	1.7	-0.8	0.4	0.3	-0.1	0.9	0.6	1.1	1.4	0.6
Alcohol intake versus 10 years previously	0.6	0.9	2.1	-0.9	0.9	-0.5	-1.4	-1.4	-0.8	0.2	-1.3	-0.1	-0.9
Medication: Paracetamol	0.6	1.1	3.1	0.0	-0.9	-1.4	1.7	1.8	1.1	0.1	0.6	0.2	-0.6
Glaucoma (self-reported)	0.6	0.7	1.7	-0.6	-0.9	-0.2	-1.1	-1.0	-1.3	-0.9	-1.0	-0.8	-0.2
Gout (self-reported)	0.6	0.8	1.9	-0.7	0.3	0.8	1.4	-0.7	-0.6	-0.4	-1.1	-1.0	-1.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	4.6	-1.1	-0.8	-0.1	2.2	0.4	0.4	0.3	-0.2	0.6	-1.9
Arm fat-free mass (right)	0.6	3.0	11.1	-1.2	-1.9	0.0	2.2	-1.4	0.2	1.5	0.3	3.3	-2.1
Whole body fat mass	0.6	2.3	7.0	1.5	0.2	0.8	-0.9	2.5	1.3	0.4	2.1	0.1	2.6
Whole body fat-free mass	0.6	3.4	16.6	0.5	-0.4	1.3	1.7	-1.0	1.3	2.8	1.4	4.1	-0.5
Breast cancer (self-reported)	0.6	0.7	2.7	0.4	-0.1	0.5	-0.7	-1.2	-0.6	-0.9	-0.9	-1.6	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	5.1	-0.9	-2.3	0.5	0.2	-1.6	-1.2	0.3	-0.6	1.1	-0.6
Whole body water mass	0.6	3.7	17.9	0.4	-0.6	1.5	1.8	-1.0	1.2	2.8	1.4	4.2	-0.7
Arm fat mass (left)	0.6	2.4	4.9	1.6	0.1	1.7	0.0	2.1	1.1	1.5	2.2	1.4	1.8
Financial situation satisfaction	0.6	0.7	2.4	0.0	0.2	-1.4	1.3	1.5	0.5	-0.2	0.7	0.4	0.0
Medication: Paracetamol	0.6	0.9	3.2	-0.7	-1.2	-1.8	1.1	1.1	0.3	-0.4	-0.2	-0.3	-0.9
Medication: Atorvastatin	0.6	0.7	3.0	0.1	1.7	-0.5	0.6	1.0	1.3	0.3	0.5	0.1	0.7
Pain experienced in last month	0.6	0.9	4.1	0.9	1.1	0.5	-2.0	-0.5	-0.1	0.3	0.2	-1.0	1.3
Heart disease (siblings)	0.6	0.7	2.1	-0.8	0.2	-0.4	-1.3	-0.8	-0.2	-0.7	-1.2	-1.5	-0.4
Bipolar Disorder (2018)	0.5	0.7	2.2	1.1	0.7	-0.8	-1.5	0.1	0.6	0.6	1.1	0.2	0.9
Depressed Affect (Nagel 2018)	0.5	1.1	3.3	-1.6	-1.0	-1.2	1.5	-0.1	-0.3	0.2	-0.6	0.4	-1.8
Ulcerative Colitis (UC)	0.5	1.0	3.6	0.3	0.0	1.6	-0.2	0.0	0.6	1.4	0.9	1.9	0.2
Schizophrenia (2014)	0.5	1.1	2.8	-0.9	-1.1	1.0	-0.2	-1.5	-1.1	-0.8	-1.2	-0.0	-1.7
Waist Hip Ratio (WHR)	0.5	2.0	5.2	0.8	0.8	2.3	-0.9	2.1	1.1	-0.7	0.4	-1.6	2.0
Hypothyroidism (self reported)	0.5	1.2	5.4	-0.9	-0.9	-0.5	1.9	0.1	-0.5	0.2	-0.5	0.4	-2.3
Lung FEV1/FVC ratio	0.5	2.7	5.7	-1.8	-0.2	-2.2	0.7	-2.2	-2.4	-0.7	-1.9	-1.4	-1.3
Neuroticism	0.5	1.1	3.7	-0.9	-0.8	-1.9	1.6	-0.3	-0.3	0.6	-0.3	0.7	-1.5
Number of treatments/medications taken	0.5	0.9	5.8	-0.8	0.8	-2.4	-0.0	1.1	0.4	-0.7	0.2	-0.5	-0.1
Fed-up feelings	0.5	0.9	2.9	-0.9	-0.2	-1.2	0.8	-0.5	-0.6	-0.6	-1.2	-0.8	-1.7
Hayfever, allergic rhinitis or eczema	0.5	1.1	3.4	0.0	0.6	-1.9	0.6	-1.1	-1.3	0.5	-0.8	0.7	-1.7
Multivitamins +/- minerals	0.5	0.7	2.6	0.3	-0.4	1.6	-1.0	-1.4	-0.7	0.3	-0.7	-0.1	-0.5
Forced vital capacity (FVC)	0.5	1.8	7.4	1.2	-1.9	2.7	-0.5	-1.0	0.4	0.1	0.4	1.6	1.0
Neuroticism score	0.5	1.1	4.9	-0.8	-0.4	-2.2	0.6	-1.0	-0.5	-0.5	-1.0	-0.4	-1.3
Trunk fat-free mass	0.5	2.7	13.8	-0.1	-0.5	1.1	1.6	-1.2	1.2	2.2	0.9	3.7	-0.8
Pulse rate	0.5	0.8	2.7	1.0	0.1	0.8	0.8	0.2	0.5	1.5	0.9	1.6	-0.2
Happiness	0.5	0.6	3.6	-0.1	0.5	-0.3	1.9	0.4	0.3	0.6	-0.1	0.6	-1.1
Asthma	0.5	1.0	2.0	1.4	0.7	1.2	-0.6	0.2	1.3	1.3	0.8	1.3	0.5
Lung cancer (father)	0.5	0.5	2.3	-0.1	0.4	0.5	1.4	1.5	0.5	0.3	0.5	-0.2	0.2
Blood clot in the leg (DVT)	0.5	0.6	2.1	-1.2	-0.9	0.1	-0.2	-1.4	-0.2	-0.1	-0.7	0.2	-1.1
Headache pain in last month	0.5	0.9	3.1	0.8	0.7	-1.0	-0.6	0.8	1.1	-0.5	0.7	-0.7	1.8
Emphysema/chronic bronchitis	0.5	0.5	1.1	-0.9	-0.3	-0.6	0.8	0.8	1.0	0.2	0.8	1.1	-0.2
Angina (self-reported)	0.5	0.7	2.1	-0.9	0.1	-1.2	-1.4	-1.2	-0.5	-0.6	-0.6	-0.3	-0.2
Migraine (self-reported)	0.5	0.7	1.8	0.1	0.7	-1.0	1.3	0.2	1.1	0.8	0.1	0.7	-1.0
Number of full sisters	0.5	0.6	1.5	1.0	-0.8	1.2	0.3	-0.4	-0.5	0.7	0.4	0.9	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.5	0.9	3.4	1.6	0.5	1.8	-0.8	-0.6	0.7	0.7	0.5	0.7	0.8
Number of self-reported non-cancer illnesses	0.5	0.8	4.3	-2.1	0.2	-1.0	0.2	0.0	-0.6	-1.0	-0.8	-0.4	-0.9
Hearing aid user	0.5	0.5	4.3	-0.4	-2.1	0.3	0.1	0.4	-0.7	-0.3	0.3	0.3	0.0
Tinnitus: Yes, now most or all of the time	0.5	0.5	1.8	-0.2	1.0	-1.0	-0.1	0.6	-0.3	-0.4	-0.9	-1.3	-0.4
Basal metabolic rate	0.5	3.0	14.3	0.7	-0.5	1.5	1.3	-0.5	1.2	2.6	1.6	3.8	-0.1
Arm fat-free mass (left)	0.5	2.6	11.3	-0.7	-1.4	0.3	1.9	-1.2	0.6	1.8	0.5	3.4	-1.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.8	0.5	0.1	0.2	1.1	0.2	0.6	0.7	1.3	1.4	0.3
Basal cell carcinoma (self-reported)	0.5	0.7	2.0	0.3	0.7	0.3	0.8	0.4	1.1	1.2	0.7	1.4	-0.1
Arm predicted mass (left)	0.5	2.7	11.5	-0.9	-1.6	0.4	1.8	-1.3	0.5	1.9	0.4	3.4	-1.7
Ovarian Cancer	0.4	0.6	1.7	0.3	0.9	-0.7	-1.1	-1.3	-0.2	-0.1	-0.8	-0.5	0.6
Prostate Cancer	0.4	0.6	1.5	-1.2	-0.9	0.8	-0.9	-0.8	-1.0	-0.6	-0.4	0.3	-0.4
BMI	0.4	2.4	6.6	1.3	0.5	0.2	0.2	2.0	1.1	2.6	2.4	1.7	1.3
Vitamin and mineral supplements	0.4	0.6	2.7	-0.6	-0.0	-1.6	-0.2	0.7	-0.1	-1.0	-0.1	-0.9	0.5
Supplements: Zinc	0.4	0.4	1.7	0.8	-1.3	-0.9	0.4	0.1	-0.4	0.2	0.7	0.6	-0.4
Severe depression (siblings)	0.4	0.5	1.8	0.4	0.3	0.8	0.7	-0.4	-0.6	1.3	0.3	0.7	-0.8
Townsend deprivation index at recruitment	0.4	0.5	2.2	0.2	1.5	0.3	-1.0	-0.8	-0.8	0.1	-0.7	-0.4	0.1
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.7	-0.2	0.3	-0.4	0.2	1.3	1.1	0.3	0.8	-0.0	1.0
Serious illness, injury or assault to yourself	0.4	0.5	1.2	-1.1	-0.4	-0.9	1.0	0.3	0.1	-0.8	-0.2	-0.2	-1.0
Medication: Atenolol	0.4	0.5	1.8	-1.3	0.6	0.2	-0.2	0.2	-0.7	-0.6	-0.8	-1.0	0.1
Waist circumference	0.4	1.4	4.1	1.0	0.1	1.5	-0.2	2.0	0.5	0.8	1.6	0.3	1.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.9	2.7	1.2	1.2	1.1	-0.0	0.8	1.7	0.4	0.8	0.2	1.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.4	0.1	0.5	-0.5	1.2	0.9	1.1	0.6	0.8	0.7	-0.2
Allergy	0.4	0.8	3.0	0.0	0.0	0.8	-0.3	1.4	0.6	-0.8	0.6	-1.1	1.7
Weight	0.4	2.0	4.5	1.2	-0.2	1.3	0.1	1.2	1.3	1.6	2.0	2.1	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.0	0.6	-1.1	0.3	0.8	-0.7	-0.7	0.6	0.2	0.9	-1.4
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	4.9	0.2	-2.2	1.8	-0.3	-1.3	-0.4	-0.2	0.0	1.4	0.7
Illnesses of mother	0.4	0.5	2.5	0.5	-0.9	0.2	0.6	-0.3	0.1	0.2	0.0	0.8	-1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	2.8	0.3	-1.7	1.4	-1.3	-1.6	-0.4	-0.1	-0.3	0.9	1.1
Trunk predicted mass	0.4	2.5	13.1	-0.2	-0.5	0.9	1.6	-1.2	1.2	2.1	0.8	3.6	-0.8
Standing height	0.4	3.7	12.0	2.4	1.5	1.9	-1.8	0.2	2.8	-0.3	1.5	0.7	3.5
Hair/balding pattern: Pattern 4	0.4	0.9	3.6	1.3	-0.3	0.8	-1.0	0.1	0.4	0.1	1.2	0.4	1.9
Birth weight of first child	0.4	0.7	1.8	0.9	-0.1	-0.0	1.1	0.8	1.3	0.9	0.6	0.9	0.3
Peak expiratory flow (PEF)	0.4	1.0	4.2	-0.3	-1.4	2.0	-0.0	-1.6	-0.8	-0.2	-0.3	0.8	-0.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	2.5	0.5	1.6	-0.4	-0.4	0.5	0.7	0.1	0.4	0.4	1.0
Number of full brothers	0.4	0.5	1.1	-0.4	-1.1	0.9	-0.0	0.4	0.6	1.0	0.8	0.9	0.3
Mean time to correctly identify matches	0.4	0.7	2.9	-0.8	1.7	-0.4	-0.3	1.0	1.3	-0.2	0.1	-0.0	0.8
Heart disease (mother)	0.4	0.5	1.7	0.0	0.0	0.4	-0.4	1.2	0.6	0.5	0.6	0.3	1.3
Medication for cholesterol	0.4	0.6	1.8	0.1	-1.4	0.5	0.6	-1.2	-0.5	0.3	-0.5	0.2	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.6	0.1	-0.1	-0.3	-1.3	0.1	0.9	-1.0	-0.4	-1.0	0.6
Smoking status: Current	0.4	0.7	1.4	1.0	0.5	0.7	0.5	-1.0	0.6	1.2	0.4	1.0	-0.8
Medication: Blood pressure	0.4	0.8	3.2	-0.5	0.2	0.1	-1.0	1.8	0.2	-0.7	0.7	-0.1	1.6
Leg fat percentage (left)	0.4	1.4	3.8	-0.8	-0.9	-0.3	-1.4	1.7	-0.4	-1.6	-0.0	-1.9	1.2
Supplements: Calcium	0.4	0.5	1.8	-0.7	-0.7	-0.5	1.1	-0.2	-0.2	0.2	-0.3	0.5	-1.4
Bipolar Disorder or Schizophrenia	0.3	0.7	2.1	-0.2	0.1	-0.2	-1.5	-1.4	-0.9	-0.7	-1.0	-0.7	-0.5
Alzheimer’s Disease (in mother)	0.3	0.3	1.0	1.0	0.3	0.4	-0.4	-1.0	-0.5	-0.0	-0.1	-0.6	0.6
Reaction Time	0.3	0.6	2.5	-0.5	1.6	-1.2	-1.0	-0.4	0.2	0.2	-0.5	-0.2	0.5
Mean Putamen Volume	0.3	0.4	1.0	0.9	-0.8	1.0	-0.9	-0.6	0.2	0.3	0.4	0.2	0.3
Blood Red Count	0.3	3.1	8.1	0.7	2.7	-2.9	-0.5	2.2	1.1	-0.1	1.3	-1.5	2.3
Respiratory disease	0.3	0.7	1.4	1.1	-0.1	1.2	-0.8	0.3	0.8	0.9	0.9	1.0	0.4
Lung FVC	0.3	1.6	7.7	-0.5	-2.8	2.0	0.1	-0.9	-0.6	-0.2	0.0	1.5	0.6
Hearing difficulty/problems: Yes	0.3	0.4	1.9	1.4	0.6	0.5	0.0	0.3	-0.9	0.1	0.4	-0.7	0.4
Pack years adult smoking proportion	0.3	0.5	1.5	0.9	1.0	0.5	1.2	0.8	0.4	0.5	0.0	-0.6	-0.1
Medication: Levothyroxine sodium	0.3	0.5	1.9	-0.6	-0.4	-0.8	1.4	0.3	0.3	-0.3	-0.3	-0.4	-1.4
Body mass index (BMI)	0.3	1.3	3.9	0.3	-0.7	0.5	1.0	1.2	0.2	1.9	1.5	2.0	-0.2
Nervous feelings	0.3	0.5	2.4	-0.9	-0.2	-1.5	0.7	-0.2	0.1	-0.4	-0.4	0.4	-0.8
Had other major operations	0.3	0.3	1.5	-0.4	0.4	-0.9	1.2	0.5	0.5	0.3	0.1	-0.1	-0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.5	-0.1	0.0	-0.9	0.5	0.1	0.4	0.9	0.3	1.2	-0.8
Fluid intelligence score	0.3	0.7	2.6	1.6	-0.4	0.9	-0.5	-0.7	0.1	1.1	0.8	0.6	0.7
Exposure to tobacco smoke at home	0.3	0.3	1.1	0.4	0.5	0.1	-0.2	1.1	0.7	0.6	0.4	0.1	0.5
Tense / ‘highly strung’	0.3	0.4	1.1	0.2	0.7	-1.0	0.5	-0.3	1.0	0.1	0.5	0.6	0.8
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.5	1.6	-0.4	0.6	-0.1	-0.8	-1.2	-0.1	0.2	0.1	0.4
Forced vital capacity (FVC), Best measure	0.3	1.2	3.8	1.0	-1.1	2.0	-1.1	-1.0	0.4	0.0	0.1	1.1	1.5
Leg fat percentage (right)	0.3	1.2	4.5	-0.1	-0.6	-0.3	-1.3	2.1	-0.1	-1.0	0.4	-1.6	1.3
Shortness of breath walking on level ground	0.3	0.3	1.5	0.0	0.0	-1.2	0.7	0.4	-0.3	0.1	0.6	0.6	0.4
Qualifications: College or University degree	0.3	1.1	4.2	0.5	-2.1	0.5	-0.9	-2.0	-0.4	-0.6	0.1	0.7	0.2
Pulse rate, automated reading	0.3	0.9	4.0	0.7	-1.2	-0.1	0.9	0.5	0.0	0.8	1.2	2.0	-0.3
Had major operations	0.3	0.3	1.8	-0.3	-0.5	1.3	0.2	-0.2	-0.1	0.4	-0.3	-0.1	-0.7
Unable to work because of sickness or disability	0.3	0.4	1.2	0.5	1.0	0.6	0.3	0.2	1.1	0.7	0.4	0.3	0.3
Commuting to job workplace: Cycle	0.3	0.3	0.9	-0.4	1.0	0.1	-0.9	-0.9	-0.2	0.4	-0.4	0.1	0.1
Pack years of smoking	0.3	0.4	1.2	0.4	0.7	0.7	0.9	0.7	0.1	-0.0	-0.3	-1.1	-0.2
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.6	0.5	-1.2	-0.3	0.8	-0.6	0.2	0.4	0.7	0.8	0.1
Fasting Glucose	0.2	0.2	0.6	-0.4	-0.0	-0.6	0.8	0.8	0.0	0.2	0.5	0.4	-0.1
Ulcerative Colitis	0.2	0.3	1.7	-0.3	-0.1	0.0	0.2	0.5	0.1	0.6	0.9	1.3	0.5
Blood White Count	0.2	1.4	6.4	0.6	2.5	-1.5	-0.5	0.0	0.5	-0.5	-0.7	-1.8	-0.3
Heel T-Score	0.2	1.7	5.1	1.9	0.8	1.5	-1.7	0.6	1.0	-0.2	0.7	-1.0	2.3
Height	0.2	3.2	7.4	2.6	0.9	2.1	-2.4	-1.3	1.7	-0.7	0.6	0.9	2.7
Hip circumference	0.2	0.7	1.4	0.8	-0.5	1.2	-0.4	1.0	-0.1	0.6	1.2	0.7	1.0
Father’s age at death	0.2	0.2	0.7	-0.3	-0.3	0.1	0.4	-0.8	-0.5	-0.2	-0.5	-0.7	-0.6
Worry too long after embarrassment	0.2	0.3	1.0	-0.4	-0.3	-0.8	1.0	0.4	-0.3	-0.4	-0.4	-0.4	-0.1
Supplements: Vitamin C	0.2	0.3	0.9	-0.5	-0.1	-0.4	0.9	0.9	0.3	-0.6	-0.1	-0.1	-0.2
Mood swings	0.2	0.3	1.0	-0.3	0.1	-1.0	0.1	-0.6	0.4	0.1	-0.7	-0.4	-1.0
Commuting to job workplace: Walk	0.2	0.3	1.3	-0.6	0.7	-1.1	-0.2	-0.1	-0.4	0.2	-0.3	-0.5	-0.0
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.9	0.3	0.1	0.8	-0.6	-0.9	-0.1	0.7	-0.4	0.5	-0.2
Number of operations (self-reported)	0.2	0.3	1.2	-0.5	0.8	-0.2	0.3	0.1	0.2	-0.4	-0.4	-1.1	-0.1
Alcohol drinker status: Previous	0.2	0.3	0.8	-0.8	0.9	-0.7	-0.1	0.5	0.2	0.2	-0.2	-0.7	0.4
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.2	1.1	-0.1	-1.0	0.0	-0.3	0.6	0.2	0.6	0.4	0.5
Alzheimer’s Disease (including proxy)	0.1	0.2	0.5	0.6	0.2	-0.4	0.7	-0.2	-0.1	-0.1	0.2	-0.5	0.5
Irritable Bowel Disease (IBD)	0.1	0.3	0.7	-0.7	-0.7	0.4	-0.4	-0.8	-0.3	-0.2	-0.7	0.4	-0.5
Blood Eosinophil Count	0.1	0.4	1.1	0.1	0.6	-1.0	0.7	1.1	0.7	0.0	0.2	-0.4	0.6
Blood Platelet Count	0.1	1.5	4.5	-0.9	1.5	-1.9	-1.5	0.9	2.1	-0.3	0.1	0.4	0.9
Supplements: Glucosamine	0.1	0.1	0.3	-0.3	0.6	-0.5	0.1	0.1	0.3	-0.3	-0.0	0.1	-0.2
Eye problems/disorders: None of the above	0.1	0.1	0.6	0.3	0.0	0.2	0.1	0.1	0.8	-0.0	0.0	0.5	-0.3
Leg fat mass (right)	0.1	0.4	2.1	0.3	-0.7	0.3	-0.2	1.4	0.2	0.2	0.9	0.1	0.8
Chest pain or discomfort	0.1	0.2	0.5	0.3	0.4	0.4	-0.7	-0.7	-0.0	0.0	-0.4	-0.4	-0.5
Mineral and other dietary supplements	0.1	0.2	0.6	0.1	0.7	-0.5	0.0	0.5	0.1	-0.3	0.3	-0.4	0.8
Osteoporosis (self-reported)	0.1	0.2	0.5	-0.7	-0.7	0.2	0.3	-0.0	0.1	0.1	0.2	0.6	-0.3
Alcohol drinker status: Never	0.1	0.1	0.5	-0.7	0.1	0.3	-0.2	0.3	-0.0	-0.3	-0.5	-0.2	-0.4
Fractured/broken bones in last 5 years	0.1	0.2	0.6	-0.4	-0.2	-0.4	0.8	0.5	0.2	0.4	0.2	0.4	-0.4
Leg fat mass (left)	0.1	0.3	1.3	0.0	-0.8	0.4	-0.4	1.1	0.1	-0.0	0.7	-0.1	0.8
Tanning	0.0	0.4	2.2	-1.5	-0.1	-0.2	-0.0	-0.1	0.1	-0.1	-0.5	0.1	-1.2

Hub : Genes

NDUFS4

Models

Trait associations