Best TWAS P=9.94e-08 · Best GWAS P=3.85e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | RP11-268J15.5 | 0.17 | 0.14 | lasso | 2 | 0.11 | 2.8e-06 | 5.1 | 5.2 | 2.1e-07 | 0.99 | 0 | 1.00 | FALSE |
| 2 | GTEx | Lung | RP11-268J15.5 | 0.27 | 0.16 | lasso | 4 | 0.15 | 1.6e-11 | 5.1 | 5.1 | 3.0e-07 | 0.98 | 0 | 1.00 | FALSE |
| 3 | GTEx | Nerve Tibial | RP11-268J15.5 | 0.18 | 0.09 | lasso | 5 | 0.08 | 1.5e-06 | 5.1 | 5.3 | 9.9e-08 | 0.96 | 0 | 1.00 | TRUE |
| 4 | GTEx | Thyroid | SH3D21 | 0.14 | 0.03 | lasso | 4 | 0.05 | 6.6e-05 | 5.1 | -5.2 | 1.7e-07 | -0.93 | 0 | 0.99 | FALSE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | RP11-268J15.5 | 0.21 | 0.16 | lasso | 5 | 0.17 | 4.3e-21 | 5.1 | 5.2 | 1.5e-07 | 0.96 | 0 | 1.00 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | SH3D21 | 0.28 | 0.18 | lasso | 5 | 0.19 | 4.1e-24 | 5.1 | -5.1 | 2.7e-07 | -0.99 | 0 | 1.00 | FALSE |