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chr1:26,104,973-27,971,502

Best TWAS P=1.71e-11 · Best GWAS P=7.46e-11 conditioned to 0.945

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NUDC	0.05	0.03	bslmm	257	0.03	7.4e-05	6.2	6.2	6.8e-10	0.89	0.04	0.94	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PIGV	0.04	0.03	bslmm	295	0.03	4.2e-05	6.2	-6.3	2.3e-10	-0.97	0.04	0.96	FALSE
3	GTEx	Adipose Subcutaneous	PIGV	0.04	0.04	lasso	6	0.03	2.6e-03	6.3	-6.0	1.7e-09	-0.98	0.04	0.94	FALSE
4	GTEx	Artery Aorta	PIGV	0.11	0.10	lasso	9	0.08	2.7e-05	6.2	-5.6	2.3e-08	-0.93	0.04	0.96	FALSE
5	GTEx	Breast Mammary Tissue	PIGV	0.10	0.14	lasso	10	0.10	7.6e-06	6.2	-6.0	1.7e-09	-0.96	0.04	0.96	FALSE
6	GTEx	Breast Mammary Tissue (Female)	PIGV	0.10	0.08	lasso	3	0.06	6.0e-03	6.2	-6.2	4.8e-10	-0.96	0.04	0.88	FALSE
7	GTEx	Colon Transverse	PIGV	0.17	0.15	lasso	2	0.14	3.4e-07	6.2	-6.2	4.6e-10	-0.96	0.04	0.96	FALSE
8	GTEx	Esophagus Gastroesophageal Junction	PIGV	0.13	0.02	lasso	10	0.01	1.2e-01	5.8	-5.5	5.1e-08	-0.94	0.03	0.84	FALSE
9	GTEx	Esophagus Mucosa	PIGV	0.16	0.15	lasso	6	0.14	7.0e-10	6.5	-6.7	2.7e-11	-1.00	0.02	0.98	FALSE
10	GTEx	Pituitary	PIGV	0.25	0.12	lasso	10	0.02	8.8e-02	6.2	-6.0	2.4e-09	-0.96	0.04	0.80	FALSE
11	GTEx	Prostate	RP1-50O24.6	0.15	0.02	lasso	9	0.02	1.1e-01	6.2	6.3	2.3e-10	0.97	0.02	0.65	FALSE
12	GTEx	Skin Sun Exposed Lower leg	PIGV	0.05	0.07	lasso	2	0.06	5.0e-06	6.4	-6.4	1.2e-10	-0.99	0.03	0.97	FALSE
13	GTEx	Skin Sun Exposed Lower leg	HMGN2	0.10	0.06	enet	12	0.08	1.8e-07	4.5	6.2	5.2e-10	0.12	0.66	0.15	TRUE
14	GTEx	Stomach	PIGV	0.09	0.14	lasso	1	0.12	1.5e-06	6.2	-6.2	4.9e-10	-0.96	0.03	0.97	FALSE
15	GTEx	Thyroid	PIGV	0.14	0.12	lasso	7	0.10	2.7e-08	5.8	-5.9	3.6e-09	-0.93	0.04	0.96	FALSE
16	GTEx	Whole Blood	PIGV	0.11	0.17	lasso	5	0.16	5.6e-15	4.8	-5.7	1.2e-08	-0.89	0.07	0.93	FALSE
17	GTEx	Whole Blood	ZDHHC18	0.04	0.02	lasso	1	0.01	5.7e-02	6.2	6.2	6.5e-10	0.98	0.03	0.94	FALSE
18	METSIM	Adipose	ZDHHC18	0.04	0.03	lasso	2	0.04	3.8e-06	5.8	6.0	1.4e-09	0.82	0.03	0.97	FALSE
19	NTR	Blood	ARID1A	0.03	0.03	enet	20	0.03	7.8e-11	6.3	-6.5	6.9e-11	-0.95	0.02	0.98	FALSE
20	ROSMAP	Brain Pre-frontal Cortex	NUDC	0.18	0.15	enet	17	0.22	2.1e-28	6.1	6.7	1.7e-11	0.85	0.03	0.97	TRUE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	GPN2	0.03	0.01	lasso	9	0.02	3.2e-03	6.2	6.2	5.9e-10	0.96	0.01	0.96	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PIGV	0.03	0.05	lasso	7	0.04	4.2e-05	6.3	-5.7	1.1e-08	-0.98	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	NUDC	0.08	0.01	blup	34	0.03	4.4e-04	2.2	5.8	5.4e-09	0.54	0.00	0.06	FALSE