[Hub]/) : Traits : Hair Pigment :

chr1:26,104,973-27,971,502

Best TWAS P=1.71e-11 · Best GWAS P=7.46e-11 conditioned to 0.945

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NUDC 0.05 0.03 bslmm 257 0.03 7.4e-05 6.2 6.2 6.8e-10 0.89 0.04 0.94 FALSE
2 CommonMind Brain Pre-frontal Cortex PIGV 0.04 0.03 bslmm 295 0.03 4.2e-05 6.2 -6.3 2.3e-10 -0.97 0.04 0.96 FALSE
3 GTEx Adipose Subcutaneous PIGV 0.04 0.04 lasso 6 0.03 2.6e-03 6.3 -6.0 1.7e-09 -0.98 0.04 0.94 FALSE
4 GTEx Artery Aorta PIGV 0.11 0.10 lasso 9 0.08 2.7e-05 6.2 -5.6 2.3e-08 -0.93 0.04 0.96 FALSE
5 GTEx Breast Mammary Tissue PIGV 0.10 0.14 lasso 10 0.10 7.6e-06 6.2 -6.0 1.7e-09 -0.96 0.04 0.96 FALSE
6 GTEx Breast Mammary Tissue (Female) PIGV 0.10 0.08 lasso 3 0.06 6.0e-03 6.2 -6.2 4.8e-10 -0.96 0.04 0.88 FALSE
7 GTEx Colon Transverse PIGV 0.17 0.15 lasso 2 0.14 3.4e-07 6.2 -6.2 4.6e-10 -0.96 0.04 0.96 FALSE
8 GTEx Esophagus Gastroesophageal Junction PIGV 0.13 0.02 lasso 10 0.01 1.2e-01 5.8 -5.5 5.1e-08 -0.94 0.03 0.84 FALSE
9 GTEx Esophagus Mucosa PIGV 0.16 0.15 lasso 6 0.14 7.0e-10 6.5 -6.7 2.7e-11 -1.00 0.02 0.98 FALSE
10 GTEx Pituitary PIGV 0.25 0.12 lasso 10 0.02 8.8e-02 6.2 -6.0 2.4e-09 -0.96 0.04 0.80 FALSE
11 GTEx Prostate RP1-50O24.6 0.15 0.02 lasso 9 0.02 1.1e-01 6.2 6.3 2.3e-10 0.97 0.02 0.65 FALSE
12 GTEx Skin Sun Exposed Lower leg PIGV 0.05 0.07 lasso 2 0.06 5.0e-06 6.4 -6.4 1.2e-10 -0.99 0.03 0.97 FALSE
13 GTEx Skin Sun Exposed Lower leg HMGN2 0.10 0.06 enet 12 0.08 1.8e-07 4.5 6.2 5.2e-10 0.12 0.66 0.15 TRUE
14 GTEx Stomach PIGV 0.09 0.14 lasso 1 0.12 1.5e-06 6.2 -6.2 4.9e-10 -0.96 0.03 0.97 FALSE
15 GTEx Thyroid PIGV 0.14 0.12 lasso 7 0.10 2.7e-08 5.8 -5.9 3.6e-09 -0.93 0.04 0.96 FALSE
16 GTEx Whole Blood PIGV 0.11 0.17 lasso 5 0.16 5.6e-15 4.8 -5.7 1.2e-08 -0.89 0.07 0.93 FALSE
17 GTEx Whole Blood ZDHHC18 0.04 0.02 lasso 1 0.01 5.7e-02 6.2 6.2 6.5e-10 0.98 0.03 0.94 FALSE
18 METSIM Adipose ZDHHC18 0.04 0.03 lasso 2 0.04 3.8e-06 5.8 6.0 1.4e-09 0.82 0.03 0.97 FALSE
19 NTR Blood ARID1A 0.03 0.03 enet 20 0.03 7.8e-11 6.3 -6.5 6.9e-11 -0.95 0.02 0.98 FALSE
20 ROSMAP Brain Pre-frontal Cortex NUDC 0.18 0.15 enet 17 0.22 2.1e-28 6.1 6.7 1.7e-11 0.85 0.03 0.97 TRUE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GPN2 0.03 0.01 lasso 9 0.02 3.2e-03 6.2 6.2 5.9e-10 0.96 0.01 0.96 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PIGV 0.03 0.05 lasso 7 0.04 4.2e-05 6.3 -5.7 1.1e-08 -0.98 0.01 0.99 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma NUDC 0.08 0.01 blup 34 0.03 4.4e-04 2.2 5.8 5.4e-09 0.54 0.00 0.06 FALSE