Best TWAS P=4.25e-46 · Best GWAS P=1.04e-49 conditioned to 0.393
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | JAZF1 | 0.17 | 0.00 | enet | 32 | 0.05 | 5.8e-04 | 9.9 | -5.3 | 9.1e-08 | -0.40 | 0.02 | 0.89 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | JAZF1-AS1 | 0.37 | 0.30 | bslmm | 578 | 0.32 | 2.4e-42 | 7.3 | -5.4 | 6.6e-08 | -0.20 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | JAZF1 | 0.04 | 0.02 | blup | 224 | 0.03 | 3.8e-06 | 7.9 | 6.2 | 5.9e-10 | 0.48 | 0.55 | 0.29 | TRUE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | JAZF1 | 0.24 | 0.08 | blup | 222 | 0.07 | 3.3e-03 | 11.2 | 5.5 | 3.1e-08 | 0.47 | 0.08 | 0.33 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | JAZF1 | 0.12 | 0.09 | lasso | 4 | 0.09 | 2.1e-09 | 13.3 | 14.3 | 4.3e-46 | 0.84 | 0.04 | 0.96 | TRUE |