Best TWAS P=9.35e-08 · Best GWAS P=5.86e-09 conditioned to 0.0204
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | ARHGEF5 | 0.11 | 0.06 | enet | 20 | 0.05 | 1.7e-04 | 5.8 | 5.1 | 2.7e-07 | 0.85 | 0 | 0.99 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ARHGEF5 | 0.08 | 0.06 | enet | 10 | 0.06 | 1.1e-07 | 5.7 | 5.3 | 9.3e-08 | 0.92 | 0 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | OR2A9P | 0.03 | 0.00 | blup | 12 | 0.02 | 2.2e-03 | -1.6 | 5.1 | 2.9e-07 | 0.78 | 0 | 0.66 | FALSE |