Best TWAS P=1.44e-08 · Best GWAS P=2.54e-28 conditioned to 1.51e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SORBS3 | 0.05 | 0.01 | blup | 536 | 0.02 | 1.5e-03 | -2.0 | -5.6 | 2.5e-08 | -0.03 | 0.46 | 0.02 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | PEBP4 | 0.43 | 0.24 | bslmm | 663 | 0.36 | 7.8e-49 | 4.6 | -5.7 | 1.4e-08 | 0.11 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | PEBP4 | 0.24 | 0.16 | lasso | 13 | 0.23 | 2.2e-22 | 3.6 | -5.2 | 2.4e-07 | 0.10 | 1.00 | 0.00 | FALSE |