Best TWAS P=7.33e-08 · Best GWAS P=5.96e-08 conditioned to 0.0634
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Lung | AP3M2 | 0.1 | 0.07 | lasso | 8 | 0.05 | 5.8e-05 | 4 | -5.2 | 2.3e-07 | -0.69 | 0.03 | 0.95 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | AP3M2 | 0.1 | 0.06 | lasso | 5 | 0.11 | 5.7e-07 | 4 | -5.4 | 7.3e-08 | -0.80 | 0.02 | 0.97 | TRUE |