Best TWAS P=1.72e-10 · Best GWAS P=3.52e-10 conditioned to 0.00266
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Transverse | LIN7C | 0.13 | 0.04 | enet | 19 | 0.08 | 0.00014 | 2.0 | 5.1 | 3.1e-07 | 0.66 | 0.03 | 0.84 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | CCDC34 | 0.06 | 0.04 | lasso | 6 | 0.03 | 0.00051 | 6.2 | 6.4 | 1.7e-10 | 0.61 | 0.00 | 0.96 | TRUE |