Best TWAS P=1.51e-13 · Best GWAS P=3.45e-16 conditioned to 0.231
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | CYBRD1 | 0.14 | 0.05 | enet | 8 | 0.10 | 5.6e-08 | -5.7 | -5.2 | 2.2e-07 | -0.16 | 0.99 | 0 | FALSE |
| 2 | NTR | Blood | CYBRD1 | 0.20 | 0.08 | lasso | 9 | 0.12 | 5.1e-37 | 3.0 | -5.3 | 1.1e-07 | -0.21 | 1.00 | 0 | TRUE |
| 3 | YFS | Blood | CYBRD1 | 0.64 | 0.35 | enet | 73 | 0.49 | 1.0e-184 | 3.0 | -5.3 | 1.2e-07 | -0.15 | 1.00 | 0 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CYBRD1 | 0.08 | 0.07 | enet | 11 | 0.07 | 3.3e-08 | 8.2 | -7.4 | 1.5e-13 | -0.88 | 0.00 | 1 | TRUE |