Best TWAS P=9.73e-35 · Best GWAS P=0 conditioned to 0
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RXFP3 | 0.12 | 0.08 | enet | 21 | 0.08 | 1.3e-09 | -2.4 | 7.8 | 5.7e-15 | 0.11 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Brain Nucleus accumbens basal ganglia | AMACR | 0.46 | 0.32 | enet | 20 | 0.30 | 8.9e-09 | 4.0 | -6.8 | 1.0e-11 | -0.20 | 0.72 | 0.03 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | AMACR | 0.04 | 0.01 | blup | 75 | 0.03 | 5.4e-04 | 2.6 | -6.7 | 2.1e-11 | -0.26 | 0.21 | 0.02 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | AMACR | 0.23 | 0.26 | blup | 72 | 0.25 | 1.0e-16 | 2.4 | -9.6 | 7.2e-22 | -0.30 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | AMACR | 0.31 | 0.23 | enet | 9 | 0.29 | 1.4e-12 | 3.9 | -12.3 | 9.7e-35 | -0.31 | 1.00 | 0.00 | TRUE |
| 6 | The Cancer Genome Atlas | Soft Tissue Sarcoma | AMACR | 0.06 | 0.04 | blup | 80 | 0.04 | 1.6e-03 | 3.9 | -5.2 | 1.7e-07 | -0.15 | 0.14 | 0.04 | TRUE |