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chr5:12,225-1,214,264

Best TWAS P=8.35e-11 · Best GWAS P=1.77e-05 conditioned to 0.566

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CTD-2228K2.7	0.73	0.18	enet	31	0.52	7.8e-50	-4.29	-5.3	9.7e-08	0.63	0.00	0.90	FALSE
2	GTEx	Adrenal Gland	SLC9A3	0.62	0.03	enet	24	0.52	1.1e-21	-4.04	-5.4	7.9e-08	0.59	0.02	0.25	FALSE
3	GTEx	Adrenal Gland	CTD-2228K2.7	0.72	0.17	enet	33	0.51	7.4e-21	-4.04	-5.7	1.2e-08	0.68	0.01	0.69	FALSE
4	GTEx	Breast Mammary Tissue	CTD-2228K2.7	0.72	0.14	enet	28	0.47	1.0e-26	-4.29	-5.2	1.6e-07	0.71	0.00	0.90	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	SLC9A3	0.56	0.00	enet	29	0.42	4.1e-15	-2.08	-5.7	1.6e-08	0.66	0.01	0.19	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	CTD-2228K2.7	0.65	0.11	enet	30	0.43	1.3e-15	-4.29	-5.7	1.2e-08	0.74	0.01	0.63	FALSE
7	GTEx	Cells Transformed fibroblasts	CTD-2228K2.7	0.69	0.07	lasso	15	0.51	5.3e-44	-4.04	-5.3	1.2e-07	0.57	0.02	0.58	FALSE
8	GTEx	Heart Atrial Appendage	SLC9A3	0.68	0.06	enet	26	0.44	1.1e-21	-4.04	-5.4	5.6e-08	0.59	0.01	0.62	FALSE
9	GTEx	Heart Atrial Appendage	CTD-2228K2.7	0.78	0.15	lasso	16	0.54	1.8e-28	-4.04	-5.2	1.5e-07	0.67	0.01	0.82	FALSE
10	GTEx	Heart Left Ventricle	SLC9A3	0.69	0.19	enet	26	0.54	7.1e-34	0.72	-5.5	4.0e-08	0.58	0.05	0.07	FALSE
11	GTEx	Heart Left Ventricle	CTD-2228K2.7	0.69	0.06	enet	22	0.51	6.4e-31	0.72	-5.5	3.2e-08	0.61	0.02	0.60	FALSE
12	GTEx	Lung	CTD-2228K2.7	0.41	0.05	enet	49	0.30	7.6e-23	-4.29	-5.6	1.7e-08	0.62	0.01	0.82	FALSE
13	GTEx	Muscle Skeletal	SLC9A3	0.53	0.09	enet	29	0.35	4.3e-35	-4.29	-5.7	1.5e-08	0.63	0.00	0.90	FALSE
14	GTEx	Muscle Skeletal	CTD-2228K2.7	0.60	0.18	lasso	14	0.39	6.6e-41	-4.29	-6.0	1.8e-09	0.74	0.00	0.90	FALSE
15	GTEx	Ovary	CTD-2228K2.7	0.29	0.03	enet	26	0.08	4.8e-03	-2.73	-5.7	9.8e-09	0.51	0.01	0.03	FALSE
16	GTEx	Pancreas	CTD-2228K2.7	0.53	0.08	enet	41	0.39	9.9e-18	-3.53	-5.1	2.9e-07	0.62	0.02	0.50	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	CTD-2228K2.7	0.49	0.16	enet	39	0.28	6.4e-16	-4.29	-6.5	8.3e-11	0.72	0.00	0.90	TRUE
18	GTEx	Skin Sun Exposed Lower leg	SLC9A3	0.61	0.09	enet	29	0.40	1.5e-35	-4.04	-5.9	4.7e-09	0.60	0.01	0.78	FALSE
19	GTEx	Skin Sun Exposed Lower leg	CTD-2228K2.7	0.62	0.24	enet	40	0.44	3.3e-39	-4.04	-5.9	3.4e-09	0.61	0.01	0.77	FALSE
20	GTEx	Spleen	SLC9A3	0.25	-0.01	enet	30	0.23	1.5e-06	-3.53	-5.6	1.8e-08	0.58	0.00	0.04	FALSE
21	GTEx	Spleen	CTD-2228K2.7	0.41	0.11	enet	38	0.23	1.7e-06	-4.29	-5.8	7.7e-09	0.68	0.00	0.22	FALSE
22	GTEx	Testis	SLC9A3	0.65	0.03	enet	37	0.46	2.2e-22	-0.25	-5.2	1.5e-07	0.56	0.02	0.52	FALSE
23	GTEx	Testis	CTD-2228K2.7	0.64	0.10	enet	35	0.40	8.3e-19	-4.29	-5.9	3.5e-09	0.68	0.00	0.90	FALSE
24	GTEx	Whole Blood	SLC9A3	0.29	0.04	enet	34	0.12	6.7e-11	-4.29	-5.9	3.1e-09	0.59	0.01	0.78	FALSE
25	GTEx	Whole Blood	CTD-2228K2.7	0.37	0.07	enet	28	0.19	2.5e-17	-4.29	-6.0	1.8e-09	0.68	0.00	0.89	FALSE