Best TWAS P=7.46e-08 · Best GWAS P=2.13e-07 conditioned to 0.142
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | AP3M2 | 0.42 | 0.38 | enet | 19 | 0.40 | 3.6e-32 | -4.1 | 5.1 | 2.8e-07 | -0.71 | 0.28 | 0.58 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | AP3M2 | 0.10 | 0.06 | lasso | 5 | 0.11 | 5.7e-07 | -4.1 | 5.4 | 7.5e-08 | -0.80 | 0.02 | 0.97 | TRUE |