Best TWAS P=3.27e-40 · Best GWAS P=1.64e-98 conditioned to 1.53e-54
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TRPS1 | 0.05 | 0.02 | enet | 19 | 0.02 | 2.4e-03 | -17 | 13.3 | 3.3e-40 | -0.66 | 0.27 | 0.38 | TRUE |
| 2 | METSIM | Adipose | TRPS1 | 0.07 | 0.01 | lasso | 5 | 0.03 | 1.8e-05 | -10 | 7.2 | 4.1e-13 | -0.38 | 0.20 | 0.12 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TRPS1 | 0.04 | 0.03 | blup | 102 | 0.01 | 9.6e-03 | -10 | 9.5 | 2.6e-21 | -0.49 | 0.07 | 0.13 | TRUE |