Best TWAS P=4.76e-18 · Best GWAS P=3.71e-18 conditioned to 0.0665
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DCT | 0.17 | 0.15 | lasso | 6 | 0.15 | 1.1e-17 | -8.7 | -8.1 | 5.1e-16 | 0.91 | 0.01 | 0.99 | FALSE |
| 2 | METSIM | Adipose | DCT | 0.17 | 0.15 | enet | 43 | 0.17 | 3.2e-24 | -8.7 | -8.2 | 2.4e-16 | 0.83 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | DCT | 0.08 | 0.07 | lasso | 3 | 0.06 | 1.4e-06 | -8.6 | -8.7 | 4.8e-18 | 0.92 | 0.01 | 0.99 | TRUE |