[Hub]/) : Traits : Alzheimer’s Disease (including proxy) :

chr11:84,971,275-86,479,920

Best TWAS P=4.29e-22 · Best GWAS P=4.09e-32 conditioned to 1.29e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 NTR Blood PICALM 0.02 0.01 blup 501 0.01 3.2e-05 6.6 7.5 8.5e-14 -0.53 0.89 0.08 FALSE
2 The Cancer Genome Atlas Brain Lower Grade Glioma PICALM 0.04 0.01 blup 87 0.02 1.9e-03 -11.1 -9.7 4.3e-22 0.69 0.00 0.98 TRUE