Best TWAS P=4.29e-22 · Best GWAS P=4.09e-32 conditioned to 1.29e-12
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | PICALM | 0.02 | 0.01 | blup | 501 | 0.01 | 3.2e-05 | 6.6 | 7.5 | 8.5e-14 | -0.53 | 0.89 | 0.08 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PICALM | 0.04 | 0.01 | blup | 87 | 0.02 | 1.9e-03 | -11.1 | -9.7 | 4.3e-22 | 0.69 | 0.00 | 0.98 | TRUE |