[Hub]/) : Traits : Alzheimer’s Disease (including proxy) :

chr1:206,975,221-208,513,728

Best TWAS P=9.2e-24 · Best GWAS P=9e-24 conditioned to 0.0272

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CR1 0.20 0.12 bslmm 485 0.14 7.2e-17 9.7 9.7 3.7e-22 0.95 0.01 0.99 FALSE
2 The Cancer Genome Atlas Brain Lower Grade Glioma CR1 0.07 0.06 lasso 3 0.06 6.4e-07 10.0 10.0 9.2e-24 0.92 0.00 1.00 TRUE