Best TWAS P=9.2e-24 · Best GWAS P=9e-24 conditioned to 0.0272
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CR1 | 0.20 | 0.12 | bslmm | 485 | 0.14 | 7.2e-17 | 9.7 | 9.7 | 3.7e-22 | 0.95 | 0.01 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CR1 | 0.07 | 0.06 | lasso | 3 | 0.06 | 6.4e-07 | 10.0 | 10.0 | 9.2e-24 | 0.92 | 0.00 | 1.00 | TRUE |