Best TWAS P=1.6e-19 · Best GWAS P=2.49e-36 conditioned to 4.13e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | BIN1 | 0.23 | 0.07 | lasso | 4 | 0.14 | 8.2e-09 | -6.8 | -6.8 | 1.1e-11 | -0.27 | 0.99 | 0 | TRUE |
| 2 | NTR | Blood | BIN1 | 0.05 | 0.04 | bslmm | 490 | 0.04 | 3.2e-12 | 9.6 | 8.4 | 4.7e-17 | 0.35 | 1.00 | 0 | FALSE |
| 3 | YFS | Blood | BIN1 | 0.63 | 0.46 | lasso | 15 | 0.48 | 9.6e-179 | 9.6 | 9.0 | 1.6e-19 | 0.41 | 1.00 | 0 | TRUE |