[Hub]/) : Traits : Alzheimer’s Disease (including proxy) :

chr1:160,452,218-161,885,352

Best TWAS P=1.81e-09 · Best GWAS P=8.37e-08 conditioned to 0.484

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous NDUFS2 0.06 0.09 lasso 4 0.07 2.0e-06 5.3 -5.4 5.3e-08 -0.97 0.00 1.00 FALSE
2 GTEx Cells Transformed fibroblasts B4GALT3 0.31 0.28 enet 16 0.30 2.0e-22 -4.5 -5.3 1.1e-07 -0.55 0.10 0.87 FALSE
3 NTR Blood FCER1G 0.17 0.14 lasso 6 0.16 3.4e-49 -4.6 -5.1 2.8e-07 -0.47 0.07 0.91 FALSE
4 The Cancer Genome Atlas Breast Invasive Carcinoma FCER1G 0.03 0.02 lasso 4 0.03 1.8e-06 5.4 -6.0 1.8e-09 -0.93 0.00 1.00 TRUE
5 The Cancer Genome Atlas Brain Lower Grade Glioma FCER1G 0.06 0.02 blup 71 0.05 2.7e-06 5.3 -5.3 1.1e-07 -0.76 0.01 0.98 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma NDUFS2 0.10 0.04 enet 9 0.07 5.3e-08 4.0 -5.1 2.9e-07 -0.71 0.01 0.99 FALSE