Best TWAS P=1.81e-09 · Best GWAS P=8.37e-08 conditioned to 0.484
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | NDUFS2 | 0.06 | 0.09 | lasso | 4 | 0.07 | 2.0e-06 | 5.3 | -5.4 | 5.3e-08 | -0.97 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | B4GALT3 | 0.31 | 0.28 | enet | 16 | 0.30 | 2.0e-22 | -4.5 | -5.3 | 1.1e-07 | -0.55 | 0.10 | 0.87 | FALSE |
| 3 | NTR | Blood | FCER1G | 0.17 | 0.14 | lasso | 6 | 0.16 | 3.4e-49 | -4.6 | -5.1 | 2.8e-07 | -0.47 | 0.07 | 0.91 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FCER1G | 0.03 | 0.02 | lasso | 4 | 0.03 | 1.8e-06 | 5.4 | -6.0 | 1.8e-09 | -0.93 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FCER1G | 0.06 | 0.02 | blup | 71 | 0.05 | 2.7e-06 | 5.3 | -5.3 | 1.1e-07 | -0.76 | 0.01 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NDUFS2 | 0.10 | 0.04 | enet | 9 | 0.07 | 5.3e-08 | 4.0 | -5.1 | 2.9e-07 | -0.71 | 0.01 | 0.99 | FALSE |