Best TWAS P=5.42e-14 · Best GWAS P=1.98e-14 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | ZBTB38 | 0.08 | 0.04 | lasso | 4 | 0.03 | 8.1e-04 | 7.5 | 7.5 | 5.4e-14 | 0.97 | 0.01 | 0.99 | TRUE |
2 | GTEx | Testis | ZBTB38 | 0.14 | 0.06 | lasso | 8 | 0.05 | 2.8e-03 | 5.8 | 6.1 | 1.0e-09 | 0.59 | 0.19 | 0.69 | FALSE |
3 | GTEx | Thyroid | ZBTB38 | 0.11 | 0.03 | enet | 32 | 0.04 | 2.9e-04 | 6.0 | 5.6 | 2.5e-08 | 0.61 | 0.06 | 0.93 | FALSE |
4 | NTR | Blood | ZBTB38 | 0.03 | 0.01 | lasso | 3 | 0.01 | 2.2e-05 | 7.6 | 7.1 | 1.1e-12 | 0.87 | 0.01 | 0.99 | FALSE |
5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | ZBTB38 | 0.04 | 0.03 | lasso | 3 | 0.04 | 3.0e-03 | 5.5 | 6.3 | 2.6e-10 | 0.59 | 0.05 | 0.33 | FALSE |