[Hub]/) : Traits : Allergy or Eczema :

chr3:195,734,915-197,161,849

Best TWAS P=4.05e-10 · Best GWAS P=1.62e-08 conditioned to 0.286

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PIGX 0.11 0.05 lasso 2 0.04 3.4e-04 -5.3 5.3 1.1e-07 -0.91 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum CEP19 0.27 0.15 lasso 4 0.15 5.3e-08 -5.6 5.6 2.0e-08 -1.00 0.01 0.99 FALSE
3 GTEx Adrenal Gland CEP19 0.24 0.17 lasso 3 0.15 4.8e-06 -5.6 5.6 2.4e-08 -0.99 0.01 0.98 FALSE
4 GTEx Artery Aorta PIGX 0.19 0.12 lasso 3 0.12 3.6e-07 -5.5 5.4 6.1e-08 -0.90 0.01 0.99 FALSE
5 GTEx Artery Aorta CEP19 0.17 0.09 lasso 2 0.05 8.5e-04 -5.2 5.4 8.6e-08 -0.95 0.02 0.98 FALSE
6 GTEx Artery Coronary CEP19 0.33 0.15 lasso 3 0.14 2.0e-05 -5.2 5.2 1.8e-07 -0.90 0.01 0.97 FALSE
7 GTEx Artery Tibial CEP19 0.11 0.07 lasso 3 0.07 5.3e-06 -5.6 5.5 3.0e-08 -0.99 0.01 0.99 FALSE
8 GTEx Brain Caudate basal ganglia CEP19 0.31 0.18 lasso 5 0.18 8.0e-06 -5.1 5.4 6.0e-08 -0.98 0.02 0.97 FALSE
9 GTEx Cells Transformed fibroblasts CEP19 0.38 0.23 lasso 6 0.24 2.2e-18 -5.6 5.2 2.2e-07 -0.96 0.01 0.99 FALSE
10 GTEx Esophagus Muscularis PIGX 0.12 0.01 lasso 5 0.02 3.7e-02 -5.5 5.3 1.3e-07 -0.87 0.01 0.96 FALSE
11 GTEx Esophagus Muscularis CEP19 0.16 0.11 lasso 4 0.07 3.4e-05 -5.2 5.4 8.0e-08 -0.96 0.02 0.98 FALSE
12 GTEx Heart Atrial Appendage CEP19 0.19 0.08 lasso 6 0.07 5.9e-04 -5.5 5.6 2.2e-08 -0.97 0.01 0.98 FALSE
13 GTEx Lung PIGX 0.21 0.08 enet 7 0.08 1.8e-06 -5.1 5.4 5.1e-08 -0.96 0.02 0.98 FALSE
14 GTEx Nerve Tibial CEP19 0.45 0.26 lasso 8 0.25 7.4e-18 -5.2 5.3 1.5e-07 -0.96 0.03 0.97 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic PIGX 0.17 0.11 lasso 3 0.13 1.7e-07 -5.5 5.7 1.5e-08 -0.96 0.01 0.99 FALSE
16 GTEx Skin Sun Exposed Lower leg PIGX 0.13 0.10 lasso 4 0.09 4.7e-08 -5.5 5.5 2.9e-08 -0.92 0.01 0.99 FALSE
17 GTEx Skin Sun Exposed Lower leg NRROS 0.07 0.02 enet 14 0.03 9.6e-04 -4.6 -5.6 2.8e-08 0.17 0.10 0.42 TRUE
18 GTEx Stomach PIGX 0.22 0.18 lasso 2 0.16 3.7e-08 -5.2 5.2 1.9e-07 -0.94 0.03 0.97 FALSE
19 GTEx Testis CEP19 0.58 0.50 lasso 2 0.50 5.6e-25 -5.5 5.5 4.1e-08 -1.00 0.01 0.99 FALSE
20 GTEx Thyroid PIGX 0.12 0.05 lasso 3 0.04 2.3e-04 -5.2 5.5 4.8e-08 -0.93 0.02 0.97 FALSE
21 GTEx Whole Blood CEP19 0.10 0.09 lasso 3 0.09 8.0e-09 -5.5 5.4 6.8e-08 -0.98 0.02 0.98 FALSE
22 METSIM Adipose CEP19 0.15 0.04 enet 14 0.09 5.4e-14 -5.2 5.9 4.4e-09 -0.82 0.03 0.97 FALSE
23 NTR Blood PIGX 0.04 0.03 bslmm 421 0.03 6.4e-10 -5.5 6.3 4.0e-10 -0.81 0.01 0.99 TRUE
24 YFS Blood PIGX 0.07 0.04 bslmm 441 0.04 4.0e-14 -5.3 5.1 2.9e-07 -0.85 0.02 0.98 FALSE
25 The Cancer Genome Atlas Colon Adenocarcinoma PIGX 0.06 0.01 blup 66 0.01 6.6e-02 -5.3 5.6 2.7e-08 -0.85 0.01 0.88 FALSE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C3orf34 0.08 0.14 lasso 5 0.15 2.3e-16 -5.2 5.3 1.3e-07 -0.94 0.03 0.97 FALSE
27 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PIGX 0.08 0.08 lasso 4 0.08 4.5e-09 -5.5 5.3 1.1e-07 -0.88 0.01 0.99 FALSE
28 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf34 0.05 0.07 lasso 1 0.06 1.1e-07 -5.5 5.5 4.0e-08 -1.00 0.01 0.99 FALSE
29 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C3orf34 0.06 0.05 lasso 2 0.02 2.8e-02 -5.6 5.5 4.0e-08 -1.00 0.01 0.94 FALSE
30 The Cancer Genome Atlas Brain Lower Grade Glioma C3orf34 0.07 0.09 lasso 2 0.09 1.2e-10 -5.5 5.7 1.2e-08 -0.96 0.01 0.99 FALSE
31 The Cancer Genome Atlas Lung Adenocarcinoma C3orf34 0.05 0.05 enet 10 0.04 1.5e-05 -5.2 5.7 1.5e-08 -0.97 0.01 0.98 FALSE
32 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C3orf34 0.04 0.04 lasso 2 0.04 2.0e-05 -5.5 5.8 7.7e-09 -0.94 0.01 0.99 FALSE
33 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PIGX 0.03 0.03 enet 8 0.04 2.6e-05 -5.5 5.7 9.0e-09 -0.83 0.01 0.97 FALSE
34 The Cancer Genome Atlas Testicular Germ Cell Tumors C3orf34 0.20 0.21 lasso 5 0.23 1.5e-08 -5.2 5.1 2.9e-07 -0.92 0.02 0.98 FALSE