Best TWAS P=4.1e-19 · Best GWAS P=1.68e-27 conditioned to 3.02e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ERMP1 | 0.10 | 0.04 | enet | 9 | 0.03 | 0.01180 | -4.6 | 5.2 | 1.8e-07 | -0.08 | 0.31 | 0.03 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | KIAA1432 | 0.11 | 0.04 | lasso | 5 | 0.03 | 0.00092 | 5.0 | 5.1 | 2.9e-07 | 0.07 | 0.58 | 0.04 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RANBP6 | 0.07 | 0.01 | blup | 396 | 0.02 | 0.00167 | -3.6 | 8.9 | 4.1e-19 | 0.06 | 0.89 | 0.00 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | GLDC | 0.11 | 0.00 | enet | 5 | 0.01 | 0.00738 | 10.9 | 7.6 | 4.1e-14 | 0.70 | 0.01 | 0.89 | TRUE |